Abstract: An orthopaedic surgical instrument includes a patella trial and drill guide that may be used to both perform a surgical trial of the patellofemoral joint and guide the surgeon in drilling a number of anchor holes in the patella of the patient.

Abstract: Embodiments of the present systems and methods may provide techniques that may provide the capability to autonomously and automatically identify cases of suspected abuse, which may then be subject to follow up review and action. For example, in an embodiment, a system for identifying potential physical abuse in a location may comprise at least one video camera provided at the location and a computer system comprising a processor, memory accessible by the processor, and computer program instructions stored in the memory and executable by the processor to cause the computer system to perform: receiving video data from the at least one video camera, identifying potential physical abuse from the video data, the identification being to within a predetermined confidence level, and transmitting information indicating that a potential human threat has been identified.

Abstract: An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms using a universal reporter strategy. In a preferred embodiment, the amplified DNA is localized at test sites in an array of sites on a microchip followed by a series of hybridization reactions that screen for the presence of a single mutation from among a number of mutations, and allow the identification of specific mutations. In addition to universal reporters, the assay may use blockers and discriminators for screening and identification of known polymorphisms.

Abstract: An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms using a universal reporter strategy. In a preferred embodiment, the amplified DNA is localized at test sites in an array of sites on a microchip followed by a series of hybridization reactions that screen for the presence of a single mutation from among a number of mutations, and allow the identification of specific mutations. In addition to universal reporters, the assay may use blockers and discriminators for screening and identification of known polymorphisms.

Abstract: An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms using a universal reporter strategy. In a preferred embodiment, the amplified DNA is localized at test sites in an array of sites on a microchip followed by a series of hybridization reactions that screen for the presence of a single mutation from among a number of mutations, and allow the identification of specific mutations. In addition to universal reporters, the assay may use blockers and discriminators for screening and identification of known polymorphisms.

Abstract: An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms using a universal reporter strategy. In a preferred embodiment, the amplified DNA is localized at test sites in an array of sites on a microchip followed by a series of hybridization reactions that screen for the presence of a single mutation from among a number of mutations, and allow the identification of specific mutations. In addition to universal reporters, the assay may use blockers and discriminators for screening and identification of known polymorphisms.

Abstract: A panelboard/switchboard assembly for accommodating bolt-on modules, plug-in modules and lugs. The panelboard/switchboard includes vertical, edge forward bus bars having a plurality of openings formed therein. The edge forward alignment allows plug-in modules to be mounted to the bus bars. The openings in the bus bars receive bolts for mounting straps to the bus bars and for mounting lugs to the bus bars. The openings have a shape having at least one linear element and receive a bolt having an anti-rotation portion with a similar shape. The interference between the opening and the anti-rotation portion of the bolt prevents the straps, and the modules connected to the straps, from rotating.

Abstract: A method and apparatus for reducing the wear within a mechanical apparatus having first and second adjacent, sealable surfaces which move relative to each other and having a seal between them.

Abstract: This invention provides methods and compounds relating to the use of deoxyribose nicotinamide adenine dinucleotide (dNAD.sup.+) analogues in NAD.sup.+ -dependent ligation reactions. The compounds and methods may be used in NAD.sup.+ -dependent ligation reactions generally, and to increase the specificity of NAD.sup.+ -dependent ligation reactions.

Abstract: This invention relates to a method of cloning DNA produced by primer extension including PCR amplified, reverse transcriptase-generated or primer extended synthetic DNA. Specifically, it relates to a method in which alkane diol residue containing oligonucleotide primers are incorporated into DNA by primer extension followed by direct cloning of the target DNA. Following transformation, the host excises the alkane diol residue with its endogenous DNA repair machinery.

Abstract: An ice pack includes a flexible base web, having a polymeric foam web connected to a bottom surface of the base web for frictional engagement with a skin portion of an individual, with at least one refrigerant housing mounted to a top surface of the base web positioned over the foam web. Fastener structure is arranged to opposed ends of the base web to secure about an individual. The base web structure is formed of various lengths to accommodate various appendage portions of an individual's body.

Abstract: A human physiologically active polypeptide, human Tumor Necrosis Factor (human TNF), comprising a specific amino acid sequence of 155 amino acid residues. The base sequence of the DNA coding for the human TNF has been determined using rabbit TNF cDNA. The human TNF can be advantageously produced on a large scale by recombinant DNA technique. The human TNF of the present invention has been found to be excellent in inducing necrosis of tumors with no toxic effect upon the normal tissues of the living body.

Abstract: A plurality of attachable brackets having an elongate body and first and second ends perpendicular to the body. The first ends have a first opening sized to fit over a plurality of lug sizes and secured to the lug by a lug nut. The second ends have a second opening. A plate has a plurality of holes positioned radially and circumferentially for alignment with lugs of various vehicles having lugs of differing radial and circumferential positions. A plurality of nuts and bolts secure the second ends to the plate. A circular support core may be inserted between the inside of the brackets for strength and a line guide ring may be attached to the vehicle for aligning a line connected to the brackets perpendicular to the brackets.

Abstract: A microscope is shown of generally clamshell-like configuration having top and bottom parts resiliently joined through a connecting structure. Hand deflection of the parts, resiliently resisted, results in relatively reduced motion between lens and specimen for focusing. The microscope may be formed as a unitary molding of resinous plastic or as a blank of foldable sections, and it may have built-in slide retainers. The light admitting aperture may be used to precisely locate a liquid specimen for viewing within the focal range of the microscope.