Abstract: A bone positioning guide may include a main body member, a shaft, and a bone engagement member. The shaft can be movably connected to the main body member and have the bone engagement member rotatably coupled to its distal end. The bone engagement member can have a surface configured to engage a bone. The main body member can also include a tip opposite the bone engagement member for engaging a second bone. In use, the bone engagement member may be positioned in contact with a medial side of a first metatarsal while the tip is positioned in contact with a lateral side of a different metatarsal, such as a second metatarsal. The shaft can then be moved to advance the bone engagement member toward the tip, causing realignment of the first metatarsal.

Abstract: An expandable introducer sheath with an interlock dilator. The present technology provides an expandable sheath with a step feature inside its distal opening, and a dilator with an interlock that includes a catch surface configured to engage with the step feature and resist further relative movement so that the body of the dilator is prevented from exiting the distal end of the expandable sheath. This interlocking engagement may allow the dilator to be used to extend and maintain tension on the expandable sheath during insertion into a patient, and then to be retracted from the expandable sheath by pulling the dilator in the opposite direction. The present technology also provides a dilator hub with a spring mechanism configured to achieve and maintain a desired tension on the expandable sheath and to prevent overextension of the expandable sheath when the dilator is being inserted into the expandable sheath.

Abstract: Methods for temporarily fixing an orientation of a bone or bones. Methods of correcting a bunion deformity. Bone positioning devices. Methods of using a bone positioning device. Bone preparation guides. Methods of using a bone preparation guide.

Abstract: A system and method that utilizes machine learning, volume prediction, input staffing and acuity data, and simulation data to align staffing coverage with forecasted coverage needs of an institution, such as a healthcare facility. The system can better match staffing coverage with staffing needs and patient demand resulting in cost savings and reducing the risk of overworking existing staff.

Abstract: The present disclosure is directed towards a distribution module assembly configured for mounting to a marine vessel and comprising a mounting bracket connected to a housing to aid in the stabilization of the marine vessel moving through water. The distribution module assembly further comprises a printed circuit board, a connector plate, and connectors which may connect to a variety of electronic components which also aid in the stabilization of the marine vessel. The printed circuit board is further configured to interface with various electronic components on the marine vessel such as a software control module, an engine control module, a navigation system, a gyroscopic stabilizer, a water engagement device, an engine, and other similar components that could provide the intended functionality and stability during operation of a marine vessel.

Abstract: An example operation may include one or more of generating, by a processor node, an identifier (ID) for an asset producer node, mapping, by the processor node, the ID to an identity of an asset producer node, receiving, by the processor node, a request from a supplier node from a plurality of supplier nodes for the asset producer node to be added to a supply blockchain, and providing entitlements to the plurality of the supplier nodes based on the mapped ID.

Abstract: A vapor ablation handpiece for assisting a physician perform vapor ablation with a vapor ablation catheter includes a vapor generating element arranged in a coil shape. A mandrel seated in the body of the handpiece affixes the vapor generating element in the coiled arrangement. A voltage difference is supplied across the length of the vapor generating element when activated, causing the vapor generating element to heat liquid therein converting the liquid to vapor. The heated condensable vapor is delivered to a target tissue through the catheter.

Abstract: A method for treating emphysema with a condensable vapor includes creating a plurality of collateral channels through the airway walls, and delivering the condensable vapor to the airways. The condensable vapor flows to the diseased parenchymal tissue through the airways and the collateral channels. Condensable vapor to contact the tissue heats the tissue, reducing it in volume. Apparatuses are described to create the openings and ablate the lung tissue.

Abstract: A restraint system for use in securing temporary flow lines that include multiple pipe sections, each pair of pipe sections connected together with a fitting or coupling such as a hammer joint coupling. The system includes multiple pluralities of endless loop slings connected end to end with a cow hitch or girth hitch knot. Disconnectable fittings (e.g., shackles) are placed every three or more slings so that easy disassembly is afforded in case of leakage or other failure. In one embodiment, a waterproof sleeve is an outer layer that surrounds or encapsulates an inner layer so that the inner layer remains dry and thus will not freeze.

Abstract: A vapor ablation handpiece for assisting a physician perform vapor ablation with a vapor ablation catheter includes a vapor generating element arranged in a coil shape. A mandrel seated in the body of the handpiece affixes the vapor generating element in the coiled arrangement. A voltage difference is supplied across the length of the vapor generating element when activated, causing the vapor generating element to heat liquid therein converting the liquid to vapor. The heated condensable vapor is delivered to a target tissue through the catheter.

Abstract: A method for treating emphysema with a condensable vapor includes creating a plurality of collateral channels through the airway walls, and delivering the condensable vapor to the airways. The condensable vapor flows to the diseased parenchymal tissue through the airways and the collateral channels. Condensable vapor to contact the tissue heats the tissue, reducing it in volume. Apparatuses are described to create the openings and ablate the lung tissue.

Abstract: The present invention relates to the field of (vector) vaccines, and especially to novel EHV's having an inactivation of UL18 and/or UL8. The present invention further concerns related expression cassettes and vectors, which are suitable to express genes of interest, especially antigen encoding sequences. The viral vectors of the present invention are useful for producing an immunogenic composition or vaccine.

Abstract: A minimally invasive medical technique for treating lung tumors includes use of multiple ablation modalities in a single procedure. Condensable vapor ablation and electrosurgical ablation are applied to treat the surface of the tumor and to debulk inner regions of the tumor, respectively.

Abstract: A screening method for identifying a target nerve to ablate in the treatment of inflammatory lung disease including chronic obstructive pulmonary disease and asthma. The method includes advancing a tool along the airway and into the vicinity of the candidate nerve. The candidate nerve is temporarily blocked or paralyzed. The patient is monitored for an adverse reaction during the step of temporarily blocking. If an adverse reaction is not observed, the candidate nerve is identified as the target nerve. In embodiments, the method further includes the step of ablating the target nerve.

Abstract: A disinfectant device includes a housing, a UV source disposed within the housing, a reflector for directing rays from the UV source downward through a bottom of the housing, a motion detector, a frequency detector, and an indicator light, said UV source specific to a non-visible light spectrum in a range of 200 nm to 222 nm. The bottom can be an open bottom or may include a glass covering. A timer can be included to display a duration for the UV source to be turned on. The device can include a protective curtain about a perimeter of the bottom of the housing. The reflector can be ellipsoidal in shape to direct the rays from the UV source downward through the bottom of the housing.

Abstract: The present invention relates to the field of (vector) vaccines, and especially to novel promoter sequences, expression cassettes and vectors, which are suitable to express genes of interest, especially antigen encoding sequences. The viral vectors of the present invention are useful for producing an immunogenic composition or vaccine.

Abstract: A vapor-based ablation method mitigates constriction of the airways for the treatment of asthma and COPD. A vapor ablation catheter is advanced along the airways, through the airway wall, and to an extra-airway target tissue. The position of the catheter is assessed to determine whether the catheter is in contact with the target tissue. In embodiments, the distal energy delivery section of the catheter is manipulated to contact an exterior surface of the target tissue, or to enter the target tissue. Once the position is confirmed, vapor is delivered to the target tissue through an egress port with a sufficient amount of energy to ablate the target tissue. The target tissue may vary and include smooth muscle surrounding the airways, and nerves that control the smooth muscle. Methods for treating lung cancer are also described including delivering a vapor at lung tumors and growths, and blood vessels feeding the lung tumors and growths.

Abstract: An example operation may include one or more of generating, by a processor node, an identifier (ID) for an asset producer node, mapping, by the processor node, the ID to an identity of an asset producer node, receiving, by the processor node, a request from a supplier node from a plurality of supplier nodes for the asset producer node to be added to a supply blockchain, and providing entitlements to the plurality of the supplier nodes based on the mapped ID.

Abstract: An example operation may include one or more of acquiring, by a processor node, identification data from an asset producer node over a supply blockchain, generating, by the processor node, a unique identifier (ID) for the asset producer node, and executing a smart contract to: map the ID to the identification data and provide an entitlement to the asset producer node to a plurality of supplier nodes based on the mapped ID.