Patents by Inventor Robert Bernstine
Robert Bernstine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8524490Abstract: Provided herein is a portable thermocycler, comprising: (i) a case; (ii) a rotary plate in the case; (iii) a plurality of heating blocks arranged in a geometric pattern disposed on the rotary plate; and (iv) at least one vessel adapted to move and contact at least two of the plurality of heating blocks; wherein each of the heating blocks comprises a heating plate maintained at a set temperature over a thermally insulating material; wherein the geometric pattern comprises a number of center heating blocks arranged in a shape defining a polygon and a number of outside heating blocks disposed around the periphery of the rotary plate; and wherein the rotary plate includes a plurality of rotating wheels adapted to rotate at least one of the vessels into contact with each of the heating blocks.Type: GrantFiled: September 16, 2009Date of Patent: September 3, 2013Assignees: X-Bar Diagnostic Systems, Inc.Inventors: James H. Lipscomb, Peter Blacklin, Michael Keating, Robert Bernstine, Richard Raffauf, Jr.
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Patent number: 8376982Abstract: An extraction method and apparatus is provided for obtaining quick, safe and highly sensitive testing of a variety of body fluids including saliva, blood, urine or other fluids for drugs of abuse or other analytes. The apparatus includes a latchable extraction wand for obtaining body fluid samples from a subject which is adapted to maximize the portion of the body fluid sample that will go into a graduated bottle containing a buffer solution, and a testing device wherein the sample will be received and into which test strips can be inserted to determine levels of drugs of abuse or other analyte in the sample. In one of the methods of the invention, energy is imparted to the sample and buffer solution, such as by shaking, and this facilitates reduction of sample viscosity, such as by promoting the breakdown of mucins when the sample is saliva.Type: GrantFiled: March 16, 2010Date of Patent: February 19, 2013Assignee: American Bio Medica CorporationInventors: Martin Gould, Robert Smalley, Robert Bernstine, Jackie Gale, John Donovan
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Patent number: 8287809Abstract: A method and device are provided for stimulating and increasing the production of saliva during immunoassay tests for drugs or other analytes wherein a scent or odor capable of stimulating saliva production is incorporated into a device for obtaining an oral sample from a test subject. The scent or odor may be impregnated into the oral sample collection device or may be part of an attachment to such a device, and the scent or odor is disposed in such a manner so as to maximize the exposure of the scent to the test subject and thus stimulate the production of saliva. The method and device of the invention are advantageous because the increased production of saliva will facilitate the testing of an oral sample for drugs or other analytes and will increase the likelihood of obtaining a complete and accurate result.Type: GrantFiled: June 11, 2007Date of Patent: October 16, 2012Assignee: American Bio Medica CorporationInventors: Martin Gould, Robert Smalley, Robert Bernstine
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Publication number: 20100172797Abstract: An extraction method and apparatus is provided for obtaining quick, safe and highly sensitive testing of a variety of body fluids including saliva, blood, urine or other fluids for drugs of abuse or other analytes. The apparatus includes a latchable extraction wand for obtaining body fluid samples from a subject which is adapted to maximize the portion of the body fluid sample that will go into a graduated bottle containing a buffer solution, and a testing device wherein the sample will be received and into which test strips can be inserted to determine levels of drugs of abuse or other analyte in the sample. In one of the methods of the invention, energy is imparted to the sample and buffer solution, such as by shaking, and this facilitates reduction of sample viscosity, such as by promoting the breakdown of mucins when the sample is saliva.Type: ApplicationFiled: March 16, 2010Publication date: July 8, 2010Inventors: Martin GOULD, Robert Smalley, Robert Bernstine, Jackie Gale, John Donovan
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Publication number: 20100136632Abstract: Provided herein is a portable thermocycler, comprising: (i) a case; (ii) a rotary plate in the case; (iii) a plurality of heating blocks arranged in a geometric pattern disposed on the rotary plate; and (iv) at least one vessel adapted to move and contact at least two of the plurality of heating blocks; wherein each of the heating blocks comprises a heating plate maintained at a set temperature over a thermally insulating material; wherein the geometric pattern comprises a number of center heating blocks arranged in a shape defining a polygon and a number of outside heating blocks disposed around the periphery of the rotary plate; and wherein the rotary plate includes a plurality of rotating wheels adapted to rotate at least one of the vessels into contact with each of the heating blocks.Type: ApplicationFiled: September 16, 2009Publication date: June 3, 2010Inventors: James H. LIPSCOMB, Richard Raffauf, SR., Peter Blacklin, Michael Keating, Robert Bernstine, Richard Raffauf, JR.
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Patent number: 7713475Abstract: A lateral flow immunoassay test device is provided that includes a housing with an elongated slot for holding a test sample collector; an elongated holder member for securing at least one immunoassay test strip therein; a first chamber for storing a first, pre-treatment reagent; and a second chamber for storing a second reagent. Methods of conducting lateral flow immunoassays are also provided. The device and methods of conducting lateral flow immunoassays as provided herein are advantageous in that they allow pre-treatment and pre-incubation of the test sample so that the sample flows onto the test strip more easily and provide for increases in the sensitivity of the assay.Type: GrantFiled: August 14, 2006Date of Patent: May 11, 2010Assignee: American Bio Medica CorporationInventors: Martin Gould, Yli Remo Vallejo, Robert Bernstine
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Patent number: 7695953Abstract: An extraction method and apparatus is provided for obtaining quick, safe and highly sensitive testing of any of a variety of body fluids including saliva, blood, urine or other fluids for drugs of abuse or other analytes. The apparatus includes a latchable extraction wand for obtaining body fluid samples from a subject which is adapted to maximize the portion of the body fluid sample that will go into a graduated bottle containing a buffer solution, and a testing device wherein the sample will be received and into which test strips can be inserted to determine levels of drugs of abuse or other analyte in the sample. In one of the methods of the invention, energy is imparted to the sample and buffer solution, such as by shaking, and this facilitates the reduction of sample viscosity, such as by promoting the breakdown of mucins when the sample is saliva.Type: GrantFiled: January 9, 2007Date of Patent: April 13, 2010Assignee: American Bio Medica CorporationInventors: Martin Gould, Robert Smalley, Robert Bernstine, Jackie Gale, John Donovan
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Patent number: 7507374Abstract: In a lateral test flow immunoassay device, a saliva sample and a buffer solution are delivered into a mixing chamber to mix with a second reagent. The resulting test mixture is allowed to incubate for a pre-determined period of time and then selectively delivered to a test strip.Type: GrantFiled: October 19, 2005Date of Patent: March 24, 2009Assignee: American Bio Medica Corp.Inventors: Martin Gould, Robert Bernstine
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Publication number: 20080166820Abstract: An extraction method and apparatus is provided for obtaining quick, safe and highly sensitive testing of any of a variety of body fluids including saliva, blood, urine or other fluids for drugs of abuse or other analytes. The apparatus includes a latchable extraction wand for obtaining body fluid samples from a subject which is adapted to maximize the portion of the body fluid sample that will go into a graduated bottle containing a buffer solution, and a testing device wherein the sample will be received and into which test strips can be inserted to determine levels of drugs of abuse or other analyte in the sample. In one of the methods of the invention, energy is imparted to the sample and buffer solution, such as by shaking, and this facilitates the reduction of sample viscosity, such as by promoting the breakdown of mucins when the sample is saliva.Type: ApplicationFiled: January 9, 2007Publication date: July 10, 2008Inventors: Martin Gould, Robert Smalley, Robert Bernstine, Jackie Gale, John Donovan
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Publication number: 20070259442Abstract: An assay device for testing of liquid samples for drugs of abuse has a transparent cylindrical container for retaining a liquid sample and a portion of the cylindrical wall is flat. A test strip holder is within the container and is flat so that its front surface corresponds to the flat portion of the container wall. Immunoassay test strips are in pockets on the front face of the strip holder and are visible through the container wall. Each test strip is enclosed in a transparent pocket which has a bottom opening through which the bottom portion of the test strip protrudes to contact the liquid sample within the container. The liquid then wicks upwardly through the test strip to react with reagents within the test strip.Type: ApplicationFiled: July 12, 2007Publication date: November 8, 2007Inventors: Martin Gould, Robert Smalley, Robert Bernstine
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Publication number: 20060292035Abstract: In a lateral test flow immunoassay device, a saliva sample and a buffer solution are delivered into a mixing chamber to mix with a second reagent.Type: ApplicationFiled: October 19, 2005Publication date: December 28, 2006Inventors: Martin Gould, Robert Bernstine
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Publication number: 20060292034Abstract: In this testing device, a saliva sample and a buffer solution are delivered from separate chambers into a mixing chamber to mix with a second reagent.Type: ApplicationFiled: June 28, 2005Publication date: December 28, 2006Inventors: Martin Gould, Yli Vallejo, Robert Bernstine
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Publication number: 20060292036Abstract: A saliva sample testing device has a base housing upon which is mounted an upper housing. The base housing has a drawer structure in which are formed reaction wells for receiving fluid specimens. The drawer may be slidable or pivotable out of this base housing to provide access to the reaction wells. In a modification the reaction wells are formed in the top surface of the base housing and the upper housing is tiltable upon or detached from the base housing to provide access to the reaction wells.Type: ApplicationFiled: May 31, 2006Publication date: December 28, 2006Inventors: Martin Gould, Robert Bernstine, Robert Smalley, Jacqueline Gale
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Publication number: 20060275922Abstract: A lateral flow immunoassay test device is provided that includes a housing with an elongated slot for holding a test sample collector; an elongated holder member for securing at least one immunoassay test strip therein; a first chamber for storing a first, pre-treatment reagent; and a second chamber for storing a second reagent. Methods of conducting lateral flow immunoassays are also provided. The device and methods of conducting lateral flow immunoassays as provided herein are advantageous in that they allow pre-treatment and pre-incubation of the test sample so that the sample flows onto the test strip more easily and provide for increases in the sensitivity of the assay.Type: ApplicationFiled: August 14, 2006Publication date: December 7, 2006Inventors: Martin Gould, Yli Vallejo, Robert Bernstine
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Patent number: 7090803Abstract: A lateral flow immunoassay test device that includes a housing with an elongated slot for holding a test sample collector; an elongated holder member for securing at least one immunoassay test strip therein; a first chamber for storing a first, pre-treatment reagent; and a second chamber for storing a second reagent. The pre-treatment reagent is contained within a rupturable enclosure. A piercing member is located within the housing that is used to rupture the enclosure in order to release the pre-treatment reagent so that the sample and pre-treatment reagent form a mixture. The second reagent may then be introduced to the mixture which is allowed to react with the second reagent for a period of time. The mixture and second reagent combination is then contacted with the immunoassay test strip.Type: GrantFiled: October 28, 2003Date of Patent: August 15, 2006Assignee: American Bio Medica CorporationInventors: Martin Gould, Yli Remo Vallejo, Robert Bernstine
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Patent number: D576948Type: GrantFiled: August 8, 2007Date of Patent: September 16, 2008Assignee: Gore Enterprise HoldingsInventor: Robert Bernstine
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Patent number: D614584Type: GrantFiled: June 2, 2008Date of Patent: April 27, 2010Assignee: Gore Enterprise Holdings, Inc.Inventors: Edward Neitzel, Robert Bernstine
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Patent number: D626091Type: GrantFiled: March 5, 2010Date of Patent: October 26, 2010Assignee: Gore Enterprise Holdings, Inc.Inventors: Edward Neitzel, Robert Bernstine
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Patent number: D851517Type: GrantFiled: December 13, 2017Date of Patent: June 18, 2019Assignee: Ventana Medical Systems, Inc.Inventors: Michael Thompson, Robert Bernstine, Samuel Psota, Richard Powers, Jeffery Klebenow, Chirayu Patel, Jenna Lefkowits
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Patent number: D872870Type: GrantFiled: December 22, 2017Date of Patent: January 14, 2020Assignee: Ventana Medical Systems, Inc.Inventors: Michael Thompson, Robert Bernstine, Samuel Psota, Richard Powers, Jeffery Klebenow, Chirayu Patel, Jenna Lefkowits