Patents by Inventor Robert Bishop

Robert Bishop has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5721236
    Abstract: A method of inhibiting Ras function and therefore inhibiting cellular growth is disclosed. The method comprises the administration of a compound of Formula 1.0 ##STR1## Also disclosed are novel compounds of the formulas: ##STR2## Also disclosed are processes for making 3-substituted compounds of the Formulas 1.1, 1.2 and 1.3.Further disclosed are novel compounds which are intermediates in the processes for making the 3-substituted compounds of Formulas 1.1, 1.2, and 1.3.
    Type: Grant
    Filed: March 24, 1995
    Date of Patent: February 24, 1998
    Assignee: Schering Corporation
    Inventors: W. Robert Bishop, Ronald J. Doll, Alan K. Mallams, F. George Njoroge, Joanne M. Petrin, John J. Piwinski, Ronald L. Wolin, Arthur G. Taveras, Stacy W. Remiszewski
  • Patent number: 5719148
    Abstract: A method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells is disclosed. The method comprises the administration of a compound of Formula 1.0: ##STR1## to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.Novel compounds of formulas 5.0, 5.1 and 5.2, wherein R is --C(R.sup.20)(R.sup.21)(R.sup.46), and 5.3, 5.3A and 5.3B, wherein R is --N(R.sup.25)(R.sup.48), are disclosed.Also disclosed are processes for making 3-substituted compounds of Formulas 5.0, 5.1, 5.2 and 5.3.Further disclosed are novel compounds which are intermediates in the process for making 3-substituted compounds of Formulas 5.0, 5.1, 5.2 and 5.3.
    Type: Grant
    Filed: March 24, 1995
    Date of Patent: February 17, 1998
    Assignee: Schering Corporation
    Inventors: W. Robert Bishop, Ronald J. Doll, Alan K. Mallams, F. George Njoroge, Joanne M. Petrin, John J. Piwinski, Ronald L. Wolin, Arthur G. Taveras, Stacy W. Remiszewski
  • Patent number: 5696121
    Abstract: A method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells is disclosed. The method comprises the administration of a compound of Formula 1.0: ##STR1## to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.Novel compounds of formulas 5.0, 5.1 and 5.2, wherein R is --C(R.sup.20)(R.sup.21)(R.sup.46), and 5.3, 5.3A and 5.3B, wherein R is --N(R.sub.25)(R.sub.48), are disclosed.Also disclosed are processes for making 3-substituted compounds of Formulas 5.0, 5.1, 5.2 and 5.3.Further disclosed are novel compounds which are intermediates in the process for making 3-substituted compounds of Formulas 5.0, 5.1, 5.2 and 5.3.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: December 9, 1997
    Assignee: Schering Corporation
    Inventors: W. Robert Bishop, Ronald J. Doll, Alan K. Mallams, F. George Njoroge, Joanne M. Petrin, John J. Piwinski, Ronald L. Wolin, Arthur G. Taveras, Stacy W. Remiszewski
  • Patent number: 5661152
    Abstract: A method of inhibiting Ras function and therefore inhibiting cellular growth is disclosed. The method comprises the administration of a compound containing a tricyclic ring system to a biological system. In particular, the method inhibits cellular growth in a mammal such as a human being.Novel compounds of the formula: ##STR1## are disclosed. Also disclosed are processes for making 3-substituted compounds of Formula 4.0.Further disclosed are novel compounds which are intermediates in the processes for making the 3-substituted compounds of Formula 4.0.
    Type: Grant
    Filed: May 19, 1995
    Date of Patent: August 26, 1997
    Assignee: Schering Corporation
    Inventors: W. Robert Bishop, Ronald J. Doll, Alan K. Mallams, F. George Njoroge, Joanne M. Petrin, John J. Piwinski
  • Patent number: 5619076
    Abstract: Connection of batteries to the DC bus lines across which capacitors are connected in power systems, such as uninterruptible power systems, is carried out using an auxiliary switch which is controlled to connect the batteries to a DC bus line through a precharge resistor momentarily before connection is made through a main connector. The preconnection of the batteries through the precharge resistor provides a controlled rate of charge of the capacitors before closing of the main connector to thereby avoid excessive surge currents. When the main connector is opened, as when the power system is prepared for transportation or long term storage, the auxiliary switch interrupts the current path from the battery through the precharge resistor and provides a current path from the DC bus line through a discharge resistor to ground to bleed down the charge on the capacitors to a desired level within a selected period of time.
    Type: Grant
    Filed: December 19, 1994
    Date of Patent: April 8, 1997
    Assignee: General Signal Power Systems, Inc.
    Inventors: David L. Layden, Michael J. Cane, Robert Bishop
  • Patent number: 5524152
    Abstract: A novel automatic inspection technique and apparatus is disclosed for differentiating differently colored regions of an object or surface (such as solid state wafers, printed circuit boards, or more general applications for distinguishing regions of one color from their neighboring or surrounding areas of different color), involving the use of at least a pair of separate detectors of light images (CCD cameras preferably) reflected from the object or surface and provided with optical filters of different colors corresponding to the differently colored regions of the object or surface; and an electronic filtering processing by multiplying the detector signals by different weighting coefficients selected to maximize the ratio between the filter responses to optimize signal contrast, and then linearly summing the multiplexed signals. Independence from wide light intensity variations and in color variations in the production or processing of the object is thereby obtained.
    Type: Grant
    Filed: August 15, 1994
    Date of Patent: June 4, 1996
    Assignee: Beltronics, Inc.
    Inventors: Robert Bishop, Richard Damon
  • Patent number: 5513572
    Abstract: An inflator (20) comprising: a pressure vessel (22) made of a thin walled steel tubing (24), sealed at one end by an end plate or cap (30). The other end of the pressure vessel sealed by a propellant housing (50). A plurality of axial bores (56a-d) exiting through an adjacent part (58) of the housing (50) and a face of the adjacent part of the housing includes a second counter bore (70) and a plurality of radial bores (72a-d) radially extend therefrom. A rupture disk assembly (100) having a central portion (102) forms a rupture disk extending into the second counter bore (70) and a radially extending outer portion (104) fitted generally flat against the face (60) .
    Type: Grant
    Filed: May 9, 1994
    Date of Patent: May 7, 1996
    Assignee: AlliedSignal Inc.
    Inventors: Richard Frantom, Robert Kremer, Klaus Ocker, Robert Bishop
  • Patent number: 5408576
    Abstract: A cabinet structure is specially adapted for receiving a plurality of IV fluid bags. When IV bags are placed inside this cabinet structure, the user turns on a power switch to begin a very specific and controlled heating cycle. A temperature indicator on the front of the cabinet allows the user to ascertain when the desired temperature has been reached. When an IV bag is desired for use, it is removed directly from the side of the cabinet through an opening approximately the size of the IV bag. A temperature sensor inside the bag compartment allows for automatic regulation of the temperature of a pad of heating filaments located along the back face of the inside the cabinet. The heating elements are covered by a rubber layer to protect the bags from melting. The cabinet structure can be fastened to any IV pole, hung on the side of an anesthesia cart or be mounted directly to a wall.
    Type: Grant
    Filed: October 28, 1992
    Date of Patent: April 18, 1995
    Inventor: Robert A. Bishop
  • Patent number: 5356076
    Abstract: An improved design for a soap dispenser for use with liquid soaps, primarily in showers, has a unique multi-position valve, and separate mixing and air entraining controls. Liquid soap stored in a reservoir is drawn into a flowing water stream by siphonic action. The amount of soap/air mixture is regulated by a mixture valve. Air in controllable proportions is added by an air entrainment valve. The proportion of air with respect to the soap is adjustable. Simultaneous control of the amount of soap/air mixed with the flowing water stream is controlled by a unique mixture valve geometry.
    Type: Grant
    Filed: March 29, 1993
    Date of Patent: October 18, 1994
    Inventor: Robert A. Bishop
  • Patent number: 5119434
    Abstract: A pattern inspection technique and apparatus, suitable for wafer and printed circuit board and related applications, employing novel intelligent imaged-pattern shrinking and expanding architecture to identify permissible line widths, spacing and in surrounding material context, and to identify defects or errors.
    Type: Grant
    Filed: December 31, 1990
    Date of Patent: June 2, 1992
    Assignee: Beltronics, Inc.
    Inventors: Robert Bishop, Richard Damon
  • Patent number: 5046120
    Abstract: To reduce the large number of pixels resulting from camera scanning of objects in which defects, features or differences are to be detected, and thus enhance processing speed, larger pixels are generated composed of groups of the smaller pixels, but with the smaller pixel information obtained from scanning conveyed by neighborhood majority binary value monitoring to the larger pixels, such that increased data rate is effected through processing the larger pixels without, however, loss of defect, feature or difference information contained in the small pixels.
    Type: Grant
    Filed: April 10, 1989
    Date of Patent: September 3, 1991
    Assignee: Beltronics, Inc.
    Inventor: Robert Bishop
  • Patent number: 4893346
    Abstract: Apparatus and method for automatically inspecting objects and identifying or recognizing known and unknown portions thereof, including defects and the like, involving storing digital signal information representing an image of the desired predetermined object shapes to be learned by an image inspecting system and recognized during scanning of objects to be inspected, and modifying the stored digital signal information to create a fictitious image of the object shapes to be learned that incorporates acceptable size or dimension variations and the like in such objects such that during the inspecting of future objects, these acceptable variations will be ignored as defects or unknown elements.
    Type: Grant
    Filed: September 2, 1987
    Date of Patent: January 9, 1990
    Assignee: Beltronics, Inc.
    Inventor: Robert Bishop
  • Patent number: 4697088
    Abstract: A method of and apparatus for discriminating sharp edge transitions produced during optical scanning, as by a CCD or the like, of differently reflective regions of a surface, such as copper conductors and resist background on printed circuit boards and similar applications, through delaying N successive sampling signals defining the edge transition of the desired edge transition regions slope and amplitude from unwanted reflections from other regions, subtracting each camera scan sampling signal from the previous Nth sample signal to produce a large difference signal only for the edge transitions, and adding such difference to the camera output signals to provide a distinctive boost to the edge transition signals which are then thresholded in a manner to insure rejection of signals from unwanted or spurious reflection regions into binary output signals unambiguously indentifying the edge transitions.
    Type: Grant
    Filed: June 24, 1985
    Date of Patent: September 29, 1987
    Assignee: Beltronics, Inc.
    Inventor: Robert Bishop
  • Patent number: 4649424
    Abstract: Apparatus for rendering pixel resolution, with high signal-to-noise ratio, independent of clock signal-induced ringing effects that tend to blur such resolution as caused by the inherent inductance in the grounding system of CCD chip apparatus and the like, by a novel pair of wide ground plane configurations and interconnections, and separate ground-plane clock pulse and measurement current flow paths.
    Type: Grant
    Filed: June 11, 1985
    Date of Patent: March 10, 1987
    Assignee: Beltronics Inc.
    Inventor: Robert Bishop
  • Patent number: 4589140
    Abstract: This disclosure is concerned with real-time high-speed inspection of objects involving storing digital signal mask information of optical scans of objects at different magnifications, but with substantially the same field of view, and comparing digital mask information obtained by run scans of objects-to-be-inspected, at different magnifications, with the stored mask information to identify known or unknown portions of the objects, with adaptability for rapid "teaching" of large sets of objects for storage and subsequent comparison with real objects under inspection.
    Type: Grant
    Filed: March 21, 1983
    Date of Patent: May 13, 1986
    Assignee: Beltronics, Inc.
    Inventors: Robert Bishop, Derek Schwenke
  • Patent number: 4537505
    Abstract: This disclosure is concerned with the optical detection of pin holes or similar aberrations in sheet material, such as metal or metalized packaging materials that are to enclose and seal contents therewithin, with the aid of a reflective-wall cavity structure over which the sheet material is placed and light-sealed and the walls of which are shaped to enable external light leaking through the pin hole or the like to become multiply reflected from the cavity walls and the underside of the sheet to impinge upon photodetecting means at an appropriate portion of the walls, thus to enable detection of such leak, and, if desired, location of the pin hole or the like.
    Type: Grant
    Filed: August 11, 1982
    Date of Patent: August 27, 1985
    Assignee: Beltronics Inc.
    Inventors: Robert Bishop, Krikor Bezjian
  • Patent number: 4484225
    Abstract: Electronic focusing for television pick-up cameras and the like is effected by removing video synchronization information and discontinuities from the video signal, bandpass filtering the sync-free video signal below television cut-off frequency, producing a current therefrom and rectifying to charge capacitance which is integrated into a voltage, and periodically discharging the voltage to indicate a measure of average value of amplitude of signal which is maximized to focus the camera lens.
    Type: Grant
    Filed: July 22, 1982
    Date of Patent: November 20, 1984
    Assignee: Beltronics, Inc.
    Inventor: Robert Bishop
  • Patent number: 4443855
    Abstract: A robotic control system and technique is disclosed involving image sensing of an object to be subjected to robotic action, to obtain analog image signals that are converted into binary image signal matrices which, through the use of a mask algorithm image processor (MAIP), are analyzed, and selected signals thereof corresponding to predetermined portions of the object defining points of interest at which robotic action is to be effected are fed to a computer to control movement of a robotic arm, tool or the like to effect some physical action at said predetermined points of interest of the object, in real time.
    Type: Grant
    Filed: May 6, 1981
    Date of Patent: April 17, 1984
    Inventors: Robert Bishop, Richard Damon