Abstract: Disclosed herein are methods of treating or preventing a disease caused by nonsense mutations, or ameliorating one or more symptoms associated therewith, that involve administering to a patient in need thereof a therapeutically or prophylactically effective amount of triamterene, or a pharmaceutically acceptable salt, hydrate, solvate, clathrate, prodrug, or polymorph thereof.

Abstract: Assays for detecting or measuring inositol phosphate, for detecting or measuring signaling pathways, for detecting or measuring the activity of phospholipase C-linked receptors and/or their cognate pathways, for detecting or measuring the activity of inositol kinases and inositol phosphatases, and for screening for compounds that modulate the activity of signaling pathways, receptors and enzymes.

Abstract: Polyethylene compositions, based on low density, high molecular weight polyethylene in admixture with a copolymer of ethylene-alkyl acrylate having a melt index of about 3 to about 24, wherein the combined alkyl acrylate content is about 16 to about 25 percent by weight and the copolymer is present in the composition in an amount sufficient to pass U.S. industry standards for stress cracking resistance, generally on the order of about 6 to about 25 percent by weight based on the combined weight of the polyethylene and the copolymer. The compositions of this invention, having improved environmental stress cracking resistance properties are particularly useful as jacketing about telephone wires and cables.

Abstract: Reprocessable thermoplastic graft copolymers of propylene polymer and ethylene copolymer are herein described. These graft copolymers are prepared by heating the propylene polymer and ethylene copolymer in the presence of select peroxides in order to graft the propylene polymer onto the ethylene copolymer.