Patents by Inventor Robert Butz
Robert Butz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11976103Abstract: Provided herein are IL-2 muteins, IL-2 mutein Fc-fusion molecules, anti-IL-2 antibodies, and complexes comprising an anti IL-2 antibody bound to an IL-2 cytokine that preferentially expand and activate T regulatory cells and are amenable to large scale production. Also provided herein are variant human IgG1 Fc molecules lacking or with highly reduced effector function and high stability despite lacking glycosylation at N297. Also provided herein are linker peptides that are glycosylated when expressed in mammalian cells. Also provided herein are methods of making and using the compositions of the present invention.Type: GrantFiled: October 7, 2020Date of Patent: May 7, 2024Assignee: Amgen Inc.Inventors: Eric Alan Butz, Christy Ann Thomson, Marc Alain Gavin, Ian Nevin Foltz, Dong Xia, Dina N. Alcorn, Randal Robert Ketchem, Ai Ching Lim, Kathy Manchulenko, Laura Sekirov, Kelly Ann Berry, Cyr Clovis Chua De Imus, Neeraj Jagdish Agrawal, Gunasekaran Kannan, Li Li
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Publication number: 20160296886Abstract: Herein are disclosed compositions of matter, processes of manufacture and processes of use of solid state admixtures that include an inorganic base and a sulfide selected from the group consisting of an ammonium sulfide, an alkali metal sulfide, an alkali-earth metal sulfide, transition metal sulfide, and a mixture thereof. The composition can include solid state inorganic bases (e.g., calcium hydroxide and sodium sesquicarbonate) and/or gaseous bases (e.g., ammonia) and, optionally, a support material for one or more of the inorganic base and sulfide. The compositions are useful for capturing environmental contaminants, for example, from the flue gas of a coal fired power plant.Type: ApplicationFiled: March 12, 2014Publication date: October 13, 2016Applicant: Novinda CorporationInventors: Thomas K. Gale, James robert Butz, Micheal A Lucarelli
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Publication number: 20160151760Abstract: Herein is described a composition effective for reducing the particulate resistivity of hydrated lime and capturing acidic gases from flue gas. The composition can include a supported carbonate that comprises 5 wt. % to 50 wt. % of a carbonate and 50 wt. % to 95 wt. % of a support; where the carbonate is an alkali metal carbonate selected from the group consisting of a carbonate, a bicarbonate, and a mixture thereof. The composition can be prepared by admixing the carbonate and the support with sufficient water and then drying. The composition can be used alone or with hydrated lime for reducing the concentration of acid gases in flue gas.Type: ApplicationFiled: December 27, 2013Publication date: June 2, 2016Applicant: Novinda CorporationInventors: James Robert Butz, Michael A. Lucarelli, Thomas K. Gale
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Publication number: 20150298616Abstract: A vehicle door assembly having a storage compartment. One vehicle door assembly includes a support structure. The vehicle door assembly also includes an open storage compartment coupled to the support structure. The open storage compartment is positioned in a middle portion of the vehicle door assembly along a vertical axis of the vehicle door assembly. Further, the open storage compartment includes a cavity that is not within an armrest.Type: ApplicationFiled: July 31, 2013Publication date: October 22, 2015Applicant: Johnson Controls Technology CompanyInventors: Arne Dassen, Jason M. Hipshier, David J. McCarthy, Kyle B. Beeck, Randy VanHoof, Andrew Robert Butz
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Publication number: 20150283500Abstract: A mercury capture system and method that includes the equipment for and the production of a mercury-sorbent metal sulfide in a flue gas conduit of a coal fired power plant. The system can include transition metal salt solution injection and sulfur solution injection apparati that can introduce transition metal salt solution and sulfur solution droplets (individually or as a co-injection) into the flue gas stream. The method can include the introduction (individually or as a co-injection) of a copper salt, an iron salt, and a sulfur compound into the flue gas stream, wherein the mercury-sorbent metal sulfide can be manufactured and reacted with mercury in the flue gas.Type: ApplicationFiled: October 9, 2013Publication date: October 8, 2015Applicant: NOVINDA CORP.Inventors: James Robert Butz, Michael A. Lucarelli
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Publication number: 20150265967Abstract: Described herein is a process for oxidizing gaseous Hg(0) in the combustion gas from a coal fired boiler. The process includes injecting into the combustion gases a particulate mercury oxidant precatalyst. The process further including, oxidizing Hg(0) in the combustion gases to an oxidized mercury selected from the group consisting of Hg(I), Hg(II) and injecting a mercury sorbent that admixes with the oxidized Hg(II) to form a oxidized-mercury/sorbent species. The oxidized-mercury/sorbent species can then be collected from the combustion (flue) gas using standard powder capture technologies.Type: ApplicationFiled: October 9, 2013Publication date: September 24, 2015Applicant: Novinda CorporationInventors: James Robert Butz, Michael A. Lucarelli
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Publication number: 20150210146Abstract: A support device for a door of a motor vehicle. One vehicle door assembly includes a first structure and a second structure positioned opposite from the first structure. The vehicle door assembly also includes a flexible support device coupled to the first and second structures. The flexible support device is configured to block movement of the first structure away from the second structure, and to enable movement of the first structure toward the second structure.Type: ApplicationFiled: July 31, 2013Publication date: July 30, 2015Inventors: Jason M. Hipshier, Kyle B. Beeck, Andrew Robert Butz
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Publication number: 20150203006Abstract: An armrest for a door of a motor vehicle. A motor vehicle includes a vehicle door assembly. Further, the vehicle door assembly includes a support structure. Moreover, the vehicle door assembly also includes an armrest slidably coupled to the support structure. The armrest may slide along the door assembly to adjust its position.Type: ApplicationFiled: July 31, 2013Publication date: July 23, 2015Inventors: Jason M. Hipshier, David J. McCarthy, Arne Dassen, Randy Vanhoof, Kyle B. Beeck, Andrew Robert Butz, Stanton Paul Boyer
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Publication number: 20140202329Abstract: A process of enhancing fly ash collection without adding SO3 to a flue gas can include providing a flue gas that includes fly ash and combustion gases from a coal fired boiler; injecting into the flue gas a particulate resistivity aid; and then collecting the fly ash and particulate resistivity aid with a cold side electrostatic precipitator (ESP).Type: ApplicationFiled: July 18, 2013Publication date: July 24, 2014Applicant: Novinda CorporationInventor: James Robert Butz
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Publication number: 20070098800Abstract: The present invention provides new formulations of injectable particles (e.g. microspheres) useful for intra-articular (i.a.) injection. The formulations are made of biocompatible polymers that biodegrade to generate NSAIDs, ad are useful for treating inflamed joints, thus providing safe, long-lasting relief of joint pain and swelling. In one embodiment, the present invention provides an injectable particle, comprising a biodegradable polymer comprising an agent selected from the group consisting of an NSAID, a COX-2 inhibitor, an anesthetic and a narcotic analgesic.Type: ApplicationFiled: October 28, 2003Publication date: May 3, 2007Inventors: Karen Giroux, Robert Butz
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Patent number: 6017721Abstract: The invention provides a new method for antiglobulin testing from serum of a potential blood transfusion recipient in which warm autoantibodies are removed from serum so as to allow identification of alloantibodies present. The method involves contacting serum from a patient with one or more ligands that bind warm autoantibodies but do not bind alloantibodies, separating the non-bound serum components from the bound warm autoantibodies, and using the warm autoantibody-depleted serum in antiglobulin testing. Suitable ligands include phospholipids, the polar head groups of phosphoglycerides, and naturally occurring and synthetic analogues of these molecules.Type: GrantFiled: October 11, 1996Date of Patent: January 25, 2000Assignee: The United States of America as represented by the Department of Health and Human ServicesInventor: Robert Butz