Abstract: A pressure sensing catheter having a proximal end and a distal end. The proximate end includes one or more leur fittings contiguous with one or more lumens disposed within the catheter, a connector coupled to a signal lead which spans the length of the pressure sensing catheter and a pressure transducer coupled at about a distal end of the pressure sensing catheter. One or more apertures are provided at about the distal end of the pressure sensing catheter to allow infusion of fluids and/or withdrawal of fluid samples contemporaneous with pressure monitoring within a blood vessel. Signals sent from the pressure transducer are converted into vascular pressure units by an electronic monitor coupled to the signal lead connector.