Patents by Inventor Robert Chao
Robert Chao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240164770Abstract: Systems, methods, and devices for delivery of an implant to a targeted area of a subject. The systems may include the implant including a plurality of bioresorbable hyaluronan-based fibers and a plurality of non-resorbable fibers, a bone fastener configured to couple the implant to bone, a soft-tissue fastener configured to couple the implant to soft tissue. The systems may include a soft-tissue fastener tool (SFT) configured to couple with and deliver the soft-tissue fastener through the implant and soft-tissue and a bone fastener tool (BFT) configured to couple with and deliver the bone fastener and the implant. The BFT may further be configured to facilitate positioning of at least a portion of the implant over the targeted area after delivery thereto, and a cannula including a cannula passage configured to receive the BFT coupled with the bone fastener and implant therethrough.Type: ApplicationFiled: November 22, 2023Publication date: May 23, 2024Inventors: Nam Chao, Steven W. Ek, Tim Brightman, Dan LeDuc, Chris Baker, Stefano Agnello, Edward Ahn, Matteo Centola, Stephen J. Kennedy, Matthew M. Mannarino, Elvira Marchetto, Sonali Puri, Robert Richard, Sara Simoncioni, Alex Goraltchouk
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Publication number: 20240156453Abstract: In one aspect, a system for delivery of an implant to a targeted area of a subject, the system includes the implant includes a plurality of bioresorbable hyaluronan-based fibers and a plurality of non-resorbable fibers, a bone fastener configured to couple the implant to bone, a soft-tissue fastener configured to couple the implant to soft tissue, a soft-tissue fastener tool (SFT) configured to couple with and deliver the soft-tissue fastener through the implant and soft-tissue, a bone fastener tool (BFT) configured to couple with and deliver the bone fastener and the implant. The BFT may further be configured to facilitate positioning of at least a portion of the implant over the targeted area after delivery thereto, and a cannula having a cannula passage. The cannula passage may be configured to receive the BFT coupled with the bone fastener and implant therethrough to secure the implant about the targeted site.Type: ApplicationFiled: November 22, 2023Publication date: May 16, 2024Inventors: Nam Chao, Steven W. Ek, Tim Brightman, Dan LeDuc, Chris Baker, Stefano Agnello, Edward Ahn, Matteo Centola, Stephen J. Kennedy, Matthew M. Mannarino, Elvira Marchetto, Sonali Puri, Robert Richard, Sara Simoncioni, Alex Goraltchouk
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Publication number: 20240077309Abstract: The present disclosure generally relates to displaying information related to a physical activity. In some embodiments, methods and user interfaces for managing the display of information related to a physical activity are described.Type: ApplicationFiled: January 12, 2023Publication date: March 7, 2024Inventors: Nicholas D. FELTON, James B. CARY, Edward CHAO, Kevin W. CHEN, Christopher P. FOSS, Eamon F. GILRAVI, Austen J. GREEN, Bradley W. GRIFFIN, Anders K. HAGLUNDS, Lori HYLAN-CHO, Stephen P. JACKSON, Matthew S. KOONCE, Paul T. NIXON, Robert M. PEARSON
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Publication number: 20170338671Abstract: An Analog MOSFET balancing method using an analog circuit technique for automatically balancing leakage currents with at least two supercapacitors coupled in series. A respective MOSFET is placed across each of the at least two supercapacitors operating in the non-linear region near its threshold voltage where the drain current of the respective MOSFET varies approximately exponentially with its gate voltage. Each respective MOSFET operates with an appropriate and approximately equal threshold voltage to the other respective MOSFET.Type: ApplicationFiled: August 9, 2017Publication date: November 23, 2017Inventor: ROBERT CHAO
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Publication number: 20160126826Abstract: A circuit for automatically balancing leakage current has at least two supercapacitors coupled in series. A respective MOSFET is placed across each of the at least two supercapacitors.Type: ApplicationFiled: October 31, 2014Publication date: May 5, 2016Inventor: ROBERT CHAO
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Patent number: 7524880Abstract: The invention provides a crystalline naphthalene-1,5-disulfonic acid salt of 2-[(S)-1-(8-methylaminooctyl)pyrrolidin-3-yl]-2,2-diphenylacetamide or a solvate thereof. This invention also provides pharmaceutical compositions comprising the salt or prepared using the salt; processes and intermediates for preparing the salt; and methods of using the salt to treat a pulmonary disorder.Type: GrantFiled: June 9, 2005Date of Patent: April 28, 2009Assignee: Theravance, Inc.Inventors: Li Li, Robert Chao, Adam Hughes, Yu-Hua Ji, Davar Khossravi, Weijiang Zhang
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Patent number: 7320990Abstract: The invention provides a crystalline naphthalene-1,5-disulfonic acid salt of biphenyl-2-ylcarbamic acid 1-{9-[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydro-quinolin-5 -yl)ethylamino]nonyl}piperidin-4-yl ester or a solvate thereof. This invention also provides pharmaceutical compositions comprising such a salt or prepared using such a salt; processes and intermediates for preparing such a salt; and methods of using such a salt to treat a pulmonary disorder.Type: GrantFiled: February 11, 2005Date of Patent: January 22, 2008Assignee: Theravance, Inc.Inventors: Robert Chao, Miroslav Rapta, Pierre-Jean Colson, Junning Lee
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Publication number: 20060229332Abstract: The invention provides a crystalline hydrochloride salt of 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid {(1S,3R,5R)-8-[(R)-2-hydroxy-3-(methanesulfonyl-methyl-amino)propyl]-8-azabicyclo[3.2.1]oct-3-yl}amide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with 5-HT4 receptor activity, and processes useful for preparing such crystalline salt forms.Type: ApplicationFiled: April 5, 2006Publication date: October 12, 2006Inventors: Paul Fatheree, S. Turner, Adam Goldblum, Robert Chao, Daniel Genov
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Publication number: 20060183901Abstract: The invention provides crystalline halide salts of 1-isopropyl-1H-indazole-3-carboxylic acid {(1S,3R,5R)-8-[2-(4-acetylpiperazin-1-yl)ethyl]-8-azabicyclo[3.2.1]oct-3-yl}amide and solvates thereof. The invention also provides pharmaceutical compositions comprising such salts, methods of using such crystalline salts to treat diseases associated with 5-HT4 receptor activity, and processes useful for preparing such crystalline salts.Type: ApplicationFiled: February 16, 2006Publication date: August 17, 2006Inventors: Paul Fatheree, S. Turner, Robert Chao, Jyanwei Liu, Hao Zhang, Daniel Genov, Junning Lee
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Publication number: 20060035931Abstract: The invention provides a crystalline 1,2-ethanedisulfonic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}-5-methoxyphenylcarbamoyl)ethyl]piperidin-4-yl ester or a solvate thereof. This invention also provides pharmaceutical compositions comprising such a salt or prepared using such a salt; processes and intermediates for preparing such a salt; and methods of using such a salt to treat a pulmonary disorder.Type: ApplicationFiled: August 15, 2005Publication date: February 16, 2006Inventors: Robert Chao, Miroslav Rapta, Pierre-Jean Colson
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Publication number: 20050277688Abstract: The invention provides a crystalline naphthalene-1,5-disulfonic acid salt of 2-[(S)-1-(8-methylaminooctyl)pyrrolidin-3-yl]-2,2-diphenylacetamide or a solvate thereof. This invention also provides pharmaceutical compositions comprising the salt or prepared using the salt; processes and intermediates for preparing the salt; and methods of using the salt to treat a pulmonary disorder.Type: ApplicationFiled: June 9, 2005Publication date: December 15, 2005Inventors: Li Li, Robert Chao, Adam Hughes, Yu-Hua Ji, Davar Khossravi, Weijiang Zhang
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Publication number: 20050192236Abstract: The antibiotic drug clindamycin is provided as a crystalline free base. Three polymorphic/pseudopolymorphic forms of crystalline clindamycin free base are disclosed. Also provided are pharmaceutical compositions comprising crystalline clindamycin free base. Processes for preparing crystalline clindamycin free base and compositions thereof are also provided along with methods for treating medical conditions with the pharmaceutical compositions.Type: ApplicationFiled: May 2, 2005Publication date: September 1, 2005Inventors: Robert Chao, Michael Hawley, Lisa Reeder, Donald Jones
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Publication number: 20050182092Abstract: The invention provides a crystalline naphthalene-1,5-disulfonic acid salt of biphenyl-2-ylcarbamic acid 1-{9-[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydro-quinolin-5-yl)ethylamino]nonyl}piperidin-4-yl ester or a solvate thereof. This invention also provides pharmaceutical compositions comprising such a salt or prepared using such a salt; processes and intermediates for preparing such a salt; and methods of using such a salt to treat a pulmonary disorder.Type: ApplicationFiled: February 11, 2005Publication date: August 18, 2005Applicant: Theravance, Inc.Inventors: Robert Chao, Miroslav Rapta, Pierre-Jean Colson, Junning Lee
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Publication number: 20050113413Abstract: This invention provides naphthalene-1,5-disulfonic acid salts of 4-{N-[7-(3-(S)-1-carbamoyl-1,1-diphenylmethyl)pyrrolidin-1-yl)hept-1-yl]-N-(isopropyl)amino}-1-(4-methoxypyrid-3-ylmethyl)piperidine, which salts are useful as muscarinic receptor antagonists. This invention is also directed to pharmaceutical compositions comprising these salt forms, methods of using these salt forms for treating medical conditions mediated by muscarinic receptors; and processes for preparing these salt forms.Type: ApplicationFiled: October 28, 2004Publication date: May 26, 2005Inventors: Richard Wilson, Julie Congdon, Mathai Mammen, Weijiang Zhang, Robert Chao
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Patent number: 4002946Abstract: The circuit and structure of a high voltage switch with latchup is disclosed for a latching driver used in a gas panel display. The driver circuit functions as a high voltage, single pole, double throw switch with memory. A plurality of the latching driver circuits may be integrated on an LSI chip. Each position lighted on a gas panel display requires two latching driver circuits which are operated in a complementary fashion by suitable logic. The latching driver circuit is comprised of a complementary transistor, high voltage output switch which is controlled by a positive feedback silicon controlled switch which serves as the latching mechanism. The structure of the latching driver is of an advanced integrated design employing a plurality of lateral complementary transistors in two isolation regions.Type: GrantFiled: October 21, 1975Date of Patent: January 11, 1977Assignee: International Business Machines CorporationInventor: Robert Chao-Chuin Liang
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Patent number: 4001868Abstract: The circuit and structure of a high voltage switch with latchup is disclosed for a latching driver used in a gas panel display. The driver circuit functions as a high voltage, single pole, double throw switch with memory. A plurality of the latching driver circuits may be integrated on an LSI chip. Each position lighted on a gas panel display requires two latching driver circuits which are operated in a complementary fashion by suitable logic. The latching driver circuit is comprised of a complementary transistor, high voltage output switch which is controlled by a positive feedback silicon controlled switch which serves as the latching mechanism. The structure of the latching driver is of an advanced integrated design employing a plurality of lateral complementary transistors in two isolation regions.Type: GrantFiled: September 24, 1975Date of Patent: January 4, 1977Assignee: International Business Machines CorporationInventor: Robert Chao-Chuin Liang