Abstract: Air cleaner assemblies, related methods, components therefor, and features thereof are described. In depicted examples, the air cleaner assemblies and components optionally use advantageous housing seal features. In some examples, a filter cartridge for an air cleaner includes a media pack extending along a longitudinal axis between opposite inlet and outlet flow ends and defining an outer perimeter with opposite straight sides and a first curved end. The filter cartridge can include a seal arrangement circumscribing the media pack outer perimeter, wherein a portion of the seal arrangement extends beyond a first plane defined by the media pack outlet flow end and a portion of the seal arrangement is disposed between the first plane and a second plane defined by the media pack inlet flow end, wherein the seal arrangement is aligned along a third plane disposed at an oblique angle to the first and second planes.

Abstract: A system and method for displaying images of internal anatomy includes an image processing device configured to provide high resolution images of the surgical field from low resolution scans during the procedure. The image processing device digitally manipulates a previously-obtained high resolution baseline image to produce many representative images based on permutations of movement of the baseline image. During the procedure a representative image is selected having an acceptable degree of correlation to the new low resolution image. The selected representative image and the new image are merged to provide a higher resolution image of the surgical field. The image processing device is also configured to provide interactive movement of the displayed image based on movement of the imaging device, and to permit placement of annotations on the displayed image to facilitate communication between the radiology technician and the surgeon.

Abstract: Various embodiments of the present technology can include systems, methods, and non-transitory computer readable media configured to receive milestones to define objects and attributes associated with the objects. The objects and the attributes can define an architecture of a system. A first table associated with a first milestone can be provided. The first table can be configured to receive a first set of objects associated with the first milestone. The first set of objects and a corresponding set of attributes for the first set of objects can be received. An indication to advance to a second milestone that follows the first milestone can be received. A second table associated with the second milestone can be provided. The second table can be configured to receive a second set of objects associated with the second milestone.

Abstract: Various embodiments of the present technology can include systems, methods, and non-transitory computer readable media configured to receive milestones to define objects and attributes associated with the objects. The objects and the attributes can define an architecture of a system. A first table associated with a first milestone can be provided. The first table can be configured to receive a first set of objects associated with the first milestone. The first set of objects and a corresponding set of attributes for the first set of objects can be received. An indication to advance to a second milestone that follows the first milestone can be received. A second table associated with the second milestone can be provided. The second table can be configured to receive a second set of objects associated with the second milestone.

Abstract: The present disclosure relates to genetically encoded low affinity, fluorescent Ca2+ indicators, which may be targeted to endoplasmic reticulum, the sarcoplasmic reticulum and/or the mitochondria. It also relates to polynucleotides, vectors and host cells which encode or include such low affinity Ca2+ indicators, and methods of detecting Ca2+ levels in a cell using such indicators.

Abstract: A novel assay for determining a molecular process using a fluorescent protein exchange assay, and a composition for use thereof, are provided. The assay provides first and second signalling proteins and an exchange protein, wherein the exchange protein interacts with the first signalling protein to form a complex, then introducing the second signalling protein, wherein in response to the molecular process, the exchange protein dissociates from the first protein and associates with the second protein. The change in signal in response to the exchange of the proteins is measured to indicate a molecular process.

Abstract: A novel assay for determining a molecular process using a fluorescent protein exchange assay, and a composition for use thereof, are provided. The assay provides first and second signalling proteins and an exchange protein, wherein the exchange protein interacts with the first signalling protein to form a complex, then introducing the second signalling protein, wherein in response to the molecular process, the exchange protein dissociates from the first protein and associates with the second protein. The change in signal in response to the exchange of the proteins is measured to indicate a molecular process.

Abstract: The present invention provides for precomputing patch solutions for potential user issues. The precomputed patch solutions can include minimum patch solutions and best-like-me patch solutions. Each patch solution can include a patch and a sufficient set of one or more dependencies of that patch.

Abstract: A novel assay for determining a molecular process using a fluorescent protein exchange assay, and a composition for use thereof, are provided. The assay provides first and second signalling proteins and an exchange protein, wherein the exchange protein interacts with the first signalling protein to form a complex, then introducing the second signalling protein, wherein in response to the molecular process, the exchange protein dissociates from the first protein and associates with the second protein. The change in signal in response to the exchange of the proteins is measured to indicate a molecular process.

Abstract: The present invention provides patch solutions for computer programs. A vendor system determines whether information regarding patches previously installed on the system is available. If the information is not available, the system delivers a completely pre-computed solution to the user computer system including a main patch set and its dependencies. If the information is available, the vendor system delivers a partially pre-computed solution including a main patch set and its dependencies except for any of said patches that have successors already installed on said system.

Abstract: The present invention relates, generally, to electrical power conversion devices and to the universal packaging of those devices for a wide range of applications yielding cost efficient inventory management of product lines consisting of a group of power conversion devices each with minor variations. More specifically, the present invention relates to a universal mounting frame for receiving a printed circuit board in a switch mode power supply. The universal frame is adapted for receiving an open frame or printed circuit board and securing the open frame within a plurality of known packaging configurations. To this end, only a single size printed circuit board is necessary for any type of switch mode power supply configurations, thereby, reducing costs associated with manufacture and testing.

Abstract: The present invention relates generally to fluorescent proteins and fluorescent protein variants, and more specifically to monomeric and dimeric forms of Anthozoan fluorescent proteins. In one aspect, the present invention provides variants of fluorescent proteins, where the variants have a reduced propensity to tetramerize, and form dimeric or monomeric structures. In a further aspect, the present invention provides variants of fluorescent proteins, the variants being characterized by more efficient maturation than corresponding fluorescent proteins from which they are derived. The invention also relates to methods of making and using such fluorescent proteins and fluorescent protein variants, including fluorescent protein monomers and dimers.

Abstract: The present invention relates generally to fluorescent proteins and fluorescent protein variants, and more specifically to monomeric and dimeric forms of Anthozoan fluorescent proteins. In one aspect, the present invention provides variants of fluorescent proteins, where the variants have a reduced propensity to tetramerize, and form dimeric or monomeric structures. In a further aspect, the present invention provides variants of fluorescent proteins, the variants being characterized by more efficient maturation than corresponding fluorescent proteins from which they are derived. The invention also relates to methods of making and using such fluorescent proteins and fluorescent protein variants, including fluorescent protein monomers and dimers.

Abstract: The present invention provides a computer system with a chronology generator for generating a chronology for a series of computer configurations.

Abstract: The present invention relates generally to fluorescent proteins and fluorescent protein variants, and more specifically to monomeric and dimeric forms of Anthozoan fluorescent proteins. In one aspect, the present invention provides variants of fluorescent proteins, where the variants have a reduced propensity to tetramerize, and form dimeric or monomeric structures. In a further aspect, the present invention provides variants of fluorescent proteins, the variants being characterized by more efficient maturation than corresponding fluorescent proteins from which they are derived. The invention also relates to methods of making and using such fluorescent proteins and fluorescent protein variants, including fluorescent protein monomers and dimers.

Abstract: The present invention relates, generally, to electrical power conversion devices and to the universal packaging of those devices for a wide range of applications yielding cost efficient inventory management of product lines consisting of a group of power conversion devices each with minor variations. More specifically, the present invention relates to a universal mounting frame for receiving a printed circuit board in a switch mode power supply. The universal frame is adapted for receiving an open frame or printed circuit board and securing the open frame within a plurality of known packaging configurations. To this end, only a single size printed circuit board is necessary for any type of switch mode power supply configurations, thereby, reducing costs associated with manufacture and testing.

Abstract: Non-oligomerizing fluorescent proteins, which are formed by operatively linking two or more monomers of a fluorescent protein, or which are derived from a fluorescent protein having at least one mutation that reduces or eliminates the ability of the fluorescent protein to oligomerize, are provided. The non-oligomerizing fluorescent proteins can be derived from a naturally occurring green fluorescent protein, a red fluorescent protein, or other fluorescent protein, or a fluorescent protein related thereto. Also provided is a fusion protein, which includes a non-oligomerizing fluorescent protein linked to at least one polypeptide of interest. In addition, a polynucleotide encoding a non-oligomerizing fluorescent protein is provided, as is a recombinant nucleic acid molecule, which includes polynucleotide encoding a non-oligomerizing fluorescent protein operatively linked to at least a second polynucleotide.

Abstract: The present invention relates generally to variant fluorescent proteins, and more specifically to monomeric and dimeric forms of Anthozoan fluorescent proteins. In one aspect, the present invention provides variants of fluorescent proteins, where the variants have a reduced propensity to tetramerize, and form dimeric or monomeric structures. The invention also relates to methods of making and using such fluorescent protein monomers and dimers.

Abstract: The present invention relates generally to variant fluorescent proteins, and more specifically to monomeric and dimeric forms of Anthozoan fluorescent proteins. In one aspect, the present invention provides variants of fluorescent proteins, where the variants have a reduced propensity to tetramerize, and form dimeric or monomeric structures. The invention also relates to methods of making and using such fluorescent protein monomers and dimers.

Abstract: The present invention relates generally to variant fluorescent proteins, and more specifically to monomeric and dimeric forms of Anthozoan fluorescent proteins. In one aspect, the present invention provides variants of fluorescent proteins, where the variants have a reduced propensity to tetramerize, and form dimeric or monomeric structures. The invention also relates to methods of making and using such fluorescent protein monomers and dimers.