Patents by Inventor Robert F. Diegelmann

Robert F. Diegelmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11167058
    Abstract: Compositions comprising clay minerals and methods for their use in promoting hemostasis are provided. The compositions comprise clay minerals such as bentonite, and facilitate blood clotting when applied to a hemorrhaging wound. Electrospun or electrosprayed materials (e.g. bandages, micron beads, etc.) which include clay minerals, and methods for the treatment of acute hemorrhage, are also provided.
    Type: Grant
    Filed: February 15, 2006
    Date of Patent: November 9, 2021
    Assignee: VIRGINIA COMMONWEALTH UNIVERSITY
    Inventors: Robert F. Diegelmann, Kevin R. Ward, Marcus E. Carr, Gary Lee Bowlin
  • Patent number: 9821084
    Abstract: Compositions comprising clay minerals and methods for their use in promoting hemostasis are provided. The compositions comprise clay minerals such as bentonite, and facilitate blood clotting when applied to a hemorrhaging wound. Electrospun or electrosprayed materials (e.g. bandages, micron beads, etc.) which include clay minerals, and methods for the treatment of acute hemorrhage, are also provided.
    Type: Grant
    Filed: June 10, 2010
    Date of Patent: November 21, 2017
    Assignee: Virginia Commonwealth University
    Inventors: Robert F. Diegelmann, Kevin R. Ward, Marcus E. Carr, Gary Lee Bowlin
  • Publication number: 20120219612
    Abstract: Compositions comprising clay minerals and methods for their use in promoting hemostasis are provided. The compositions comprise clay minerals such as bentonite, and facilitate blood clotting when applied to a hemorrhaging wound. Electrospun or electrosprayed materials (e.g. bandages, micron beads, etc.) which include clay minerals, and methods for the treatment of acute hemorrhage, are also provided.
    Type: Application
    Filed: May 10, 2012
    Publication date: August 30, 2012
    Inventors: Robert F. Diegelmann, Kevin R. Ward, Marcus E. Carr, Gary Lee Bowlin
  • Publication number: 20100292624
    Abstract: Compositions comprising clay minerals and methods for their use in promoting hemostasis are provided. The compositions comprise clay minerals such as bentonite, and facilitate blood clotting when applied to a hemorrhaging wound. Electrospun or electrosprayed materials (e.g. bandages, micron beads, etc.) which include clay minerals, and methods for the treatment of acute hemorrhage, are also provided.
    Type: Application
    Filed: June 10, 2010
    Publication date: November 18, 2010
    Inventors: Robert F. Diegelmann, Kevin R. Ward, Marcus E. Carr, Gary Lee Bowlin
  • Publication number: 20090155342
    Abstract: Compositions comprising clay minerals and methods for their use in promoting hemostasis are provided. The compositions comprise clay minerals such as bentonite, and facilitate blood clotting when applied to a hemorrhaging wound. Electrospun or electrosprayed materials (e.g. bandages, micron beads, etc.) which include clay minerals, and methods for the treatment of acute hemorrhage, are also provided.
    Type: Application
    Filed: February 15, 2006
    Publication date: June 18, 2009
    Applicant: Virginia Commonwealth University
    Inventors: Robert F. Diegelmann, Kevin R. Ward, Marcus E. Carr, Gary Lee Bowlin
  • Publication number: 20080319476
    Abstract: The invention generally relates to compositions and methods for promoting hemostasis and sealing a wound by producing an adhesive cast. In particular, the invention provides compositions comprising clay minerals with specified particle sizes, which, when applied to a bleeding area, allow for a desired result in at least one of the following activities: stopping blood flow from a wound, forming a cohesive mass, sealing a wound, promoting coagulant activity, sorbing a body fluid, and adhering to tissue. For example, the desired result can be sealing the wound using an adhesive cast made of clay minerals mixed with blood or other wound fluids.
    Type: Application
    Filed: May 22, 2008
    Publication date: December 25, 2008
    Inventors: Kevin R. Ward, Richard Brown, Robert F. Diegelmann, Gary L. Bowlin
  • Patent number: 6911437
    Abstract: Sequestrants and inhibitors of protease are applied to the wound site through the use of wound dressing based carrier systems to which they may be optionally ionically or covalently bound for the purpose of the initiation or enhancement of healing associated with chronic non-healing wounds.
    Type: Grant
    Filed: December 13, 2001
    Date of Patent: June 28, 2005
    Assignees: The United States of America as represented by the Secretary of Agriculture, Virginia Commonwealth University
    Inventors: J. Vincent Edwards, Robert F. Diegelmann, I. Kelman Cohen, Dorne R. Yager
  • Publication number: 20030206944
    Abstract: The invention provides wound dressings and methods of their use, especially for the treatment of chronic, non-healing wounds. The wound dressings are composed of a support matrix, such as cotton cellulose, and an active agent associated with the support matrix. The active agent may be a protease inhibitor or a protease sequestrant, in particular an inhibitor or sequestrant of a neutrophil-derived cationic protease such as elastase.
    Type: Application
    Filed: May 29, 2003
    Publication date: November 6, 2003
    Inventors: Kelman I. Cohen, Robert F. Diegelmann, Dorne Yager, Judson Vincent Edwards
  • Patent number: 6627785
    Abstract: Sequestrants and inhibitors of protease are applied to the wound site through the use of wound dressing based carrier systems to which they may be optionally ionically or covalently bound for the purpose of the initiation or enhancement of healing associated with chronic non-healing wounds.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: September 30, 2003
    Assignees: Virginia Commwealth University, The United States of America as represented by the Secretary of Agriculture
    Inventors: J. Vincent Edwards, Robert F. Diegelmann, I. Kelman Cohen, Dorne R. Yager
  • Patent number: 6599523
    Abstract: The invention provides wound dressings and methods of their use, especially for the treatment of chronic, non-healing wounds. The wound dressings are composed of a support matrix, such as cotton cellulose, and an active agent associated with the support matrix. The active agent may be a protease inhibitor or a protease sequestrant, in particular an inhibitor or sequestrant of a neutrophil-derived cationic protease such as elastase.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: July 29, 2003
    Assignees: Virginia Commonwealth University, The United States of America as represented by the Department of Agriculture
    Inventors: Kelman I. Cohen, Robert F. Diegelmann, Dorne Yager, Judson Vincent Edwards
  • Publication number: 20020064551
    Abstract: Sequestrants and inhibitors of protease are applied to the wound site through the use of wound dressing based carrier systems to which they may be optionally ionically or covalently bound for the purpose of the initiation or enhancement of healing associated with chronic non-healing wounds.
    Type: Application
    Filed: December 13, 2001
    Publication date: May 30, 2002
    Inventors: J. Vincent Edwards, Robert F. Diegelmann, I. Kelman Cohen, Dorne R. Yager
  • Publication number: 20020012693
    Abstract: The invention provides wound dressings and methods of their use, especially for the treatment of chronic, non-healing wounds. The wound dressings are composed of a support matrix, such as cotton cellulose, and an active agent associated with the support matrix. The active agent may be a protease inhibitor or a protease sequestrant, in particular an inhibitor or sequestrant of a neutrophil-derived cationic protease such as elastase.
    Type: Application
    Filed: February 28, 2001
    Publication date: January 31, 2002
    Inventors: Kelman I. Cohen, Robert F. Diegelmann, Dorne Yager, Judson Vincent Edwards