Patents by Inventor Robert F. Kelley

Robert F. Kelley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20200299409
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Application
    Filed: February 13, 2020
    Publication date: September 24, 2020
    Inventors: Xiaocheng CHEN, Mark S. DENNIS, Allen J. EBENS, Jr., Teemu T. JUNTTILA, Robert F. KELLEY, Mary A. MATHIEU
  • Nucleic acids encoding anti-polyubiquitin antibodies
    Patent number: 10738106
    Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: August 11, 2020
    Assignee: Genentech, Inc.
    Inventors: Robert F. Kelley, Vishva Dixit, Marissa L. Matsumoto
  • Anti-factor D antibody variant conjugates and uses thereof
    Patent number: 10654932
    Abstract: The disclosure relates to antibody-polymer conjugates comprising one or more anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: May 19, 2020
    Assignee: Genentech, Inc.
    Inventors: Philip E. Hass, Robert F. Kelley, Justin M. Scheer, Whitney Shatz, Devin Tesar, Menno van Lookeren Campagne
  • Anti-CLL-1 Antibodies and Methods of Use
    Publication number: 20200148774
    Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
    Type: Application
    Filed: October 21, 2019
    Publication date: May 14, 2020
    Applicant: Genentech, Inc.
    Inventors: Robert F. Kelley, Steven R. Leong, Wei-Ching Liang, Mary Mathieu, Andrew G. Polson, Bing Zheng, Xiaocheng Chen, Cecilia Pui Chi Chiu, Mark S. Dennis, Allen Ebens, Yan Wu
  • Anti-CD3 antibodies and methods of use
    Patent number: 10640572
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: May 5, 2020
    Assignee: Genentech, Inc.
    Inventors: Xiaocheng Chen, Mark S. Dennis, Allen J. Ebens, Jr., Teemu T. Junttila, Robert F. Kelley, Mary A. Mathieu
  • ANTI-FACTOR D ANTIBODY VARIANT CONJUGATES AND USES THEREOF
    Publication number: 20200115462
    Abstract: The disclosure relates to antibody-polymer conjugates comprising one or more anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
    Type: Application
    Filed: December 30, 2019
    Publication date: April 16, 2020
    Inventors: Philip E. Hass, Robert F. Kelley, Justin M. Scheer, Whitney Shatz, Devin Tesar, Menno van Lookeren Campagne
  • ANTI-HtrA1 ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20190375856
    Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.
    Type: Application
    Filed: August 19, 2019
    Publication date: December 12, 2019
    Inventors: Robert F. KELLEY, Daniel K. KIRCHHOFER, Joyce LAI, Chingwei V. LEE, Wei-Ching LIANG, Michael T. LIPARI, Kelly M. LOYET, Tao SAI, Menno VAN LOOKEREN CAMPAGNE, Yan WU, Germaine FUH
  • Anti-CLL-1 antibodies and methods of use
    Patent number: 10501545
    Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
    Type: Grant
    Filed: June 14, 2016
    Date of Patent: December 10, 2019
    Assignee: Genentech, Inc.
    Inventors: Robert F. Kelley, Steven R. Leong, Wei-Ching Liang, Mary Mathieu, Andrew G. Polson, Bing Zheng, Xiaocheng Chen, Cecilia Pui Chi Chiu, Mark S. Dennis, Allen Ebens, Yan Wu
  • Anti-HtrA1 antibodies and methods of use thereof
    Patent number: 10421822
    Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: September 24, 2019
    Assignee: Genetech, Inc.
    Inventors: Robert F. Kelley, Daniel K. Kirchhofer, Joyce Lai, Chingwei V. Lee, Wei-Ching Liang, Michael T. Lipari, Kelly M. Loyet, Tao Sai, Menno Van Lookeren Campagne, Yan Wu, Germaine Fuh
  • Anti-HtrA1 antibodies and methods of use thereof
    Patent number: 10421821
    Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: September 24, 2019
    Assignee: Genentech, Inc.
    Inventors: Robert F. Kelley, Daniel K. Kirchhofer, Joyce Lai, Chingwei V. Lee, Wei-Ching Liang, Michael T. Lipari, Kelly M. Loyet, Tao Sai, Menno Van Lookeren Campagne, Yan Wu, Germaine Fuh
  • Anti-factor D antibodies and conjugates
    Patent number: 10407510
    Abstract: The invention provides anti-Factor D antibodies and conjugates and methods of using the same.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: September 10, 2019
    Assignee: Genentech, Inc.
    Inventors: Robert F. Kelley, Whitney Shatz, Devin Tesar, Justin M. Scheer, Michelle Dion
  • ANTI-CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20190112389
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Application
    Filed: September 27, 2018
    Publication date: April 18, 2019
    Inventors: Xiaocheng CHEN, Mark S. DENNIS, Allen J. EBENS, JR., Teemu T. JUNTTILA, Robert F. KELLEY, Mary A. MATHIEU, Liping L. SUN
  • Anti-Polyubiquitin Antibodies and Methods of Use
    Publication number: 20190100578
    Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.
    Type: Application
    Filed: September 14, 2018
    Publication date: April 4, 2019
    Applicant: Genentech, Inc.
    Inventors: Vishva Dixit, Robert F. Kelley, Marissa L. Matsumoto
  • ANTI-HtrA1 ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20190048097
    Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.
    Type: Application
    Filed: October 23, 2018
    Publication date: February 14, 2019
    Inventors: Robert F. Kelley, Daniel K. Kirchhofer, Joyce Lai, Chingwei V. Lee, Wei-Ching Liang, Michael T. Lipari, Kelly M. Loyet, Tao Sai, Menno Van Lookeren Campagne, Yan Wu, Germaine Fuh
  • Methods and Compositions for Targeting Polyubiquitin
    Publication number: 20190023774
    Abstract: Anti-K63-linked polyubiquitin monoclonal antibodies, and methods for using the antibodies, are provided.
    Type: Application
    Filed: June 28, 2018
    Publication date: January 24, 2019
    Applicant: Genentech, Inc.
    Inventors: Robert F. Kelley, Marissa L. Matsumoto
  • ANTI-CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20190016823
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Application
    Filed: September 27, 2018
    Publication date: January 17, 2019
    Inventors: Xiaocheng CHEN, Mark S. DENNIS, Allen J. EBENS, JR., Teemu T. JUNTTILA, Robert F. KELLEY, Mary A. MATHIEU, Liping L. SUN
  • Anti-factor D antibodies
    Patent number: 10179821
    Abstract: The invention relates to anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: January 15, 2019
    Assignee: GENENTECH, INC.
    Inventors: Robert F Kelley, Menno van Lookeren Campagne, Justin M Scheer, Philip E Hass, Devin Tesar
  • Anti-CD3 antibodies and methods of use
    Patent number: 10174124
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: January 8, 2019
    Assignee: Genentech, Inc.
    Inventors: Xiaocheng Chen, Mark S. Dennis, Allen J. Ebens, Jr., Robert F. Kelley, Mary A. Mathieu, Liping L. Sun
  • Anti-polyubiquitin antibodies and methods of use
    Patent number: 10100105
    Abstract: The invention provides anti-polyubiquitin antibodies and methods of using the same.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: October 16, 2018
    Assignee: Genentech, Inc.
    Inventors: Vishva Dixit, Robert F. Kelley, Marissa L. Matsumoto
  • Methods and compositions for targeting polyubiquitin
    Patent number: 10035849
    Abstract: Anti-K63-linked polyubiquitin monoclonal antibodies, and methods for using the antibodies, are provided.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: July 31, 2018
    Assignee: Genentech, Inc.
    Inventors: Robert F. Kelley, Marissa Matsumoto