Patents by Inventor Robert F. Keyes

Robert F. Keyes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acetyl-CoA carboxylase (ACC) inhibitors and their use in diabetes, obesity and metabolic syndrome
    Patent number: 8207350
    Abstract: The present invention relates to compounds of formula (I) which inhibit acetyl-CoA carboxylase (ACC) and are useful for the prevention or treatment of metabolic syndrome, type II diabetes, obesity, atherosclerosis and cardiovascular diseases in humans.
    Type: Grant
    Filed: October 27, 2008
    Date of Patent: June 26, 2012
    Assignee: Abbott Laboratories
    Inventors: Robert F. Keyes, Yu Gui Gu, Hing L. Sham
  • Antibacterial compounds
    Patent number: 7737159
    Abstract: Bacterial protein synthesis-inhibiting compounds having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates in the processes, compositions containing the compounds, and methods of using the compounds are disclosed.
    Type: Grant
    Filed: February 15, 2007
    Date of Patent: June 15, 2010
    Assignee: Abbott Laboratories
    Inventors: David D. Anderson, Bruce A. Beutel, Curt S. Cooper, Yu-Gui Gu, Mira M. Hinman, Douglas M. Kalvin, Robert F. Keyes, Xenia B. Searle, Rolf Wagner
  • Novel acetyl-CoA Carboxylase (ACC) Inhibitors and their use in Diabetes, Obesity and Metabolic Syndrome
    Publication number: 20090048298
    Abstract: The present invention relates to compounds of formula (I) which inhibit acetyl-CoA carboxylase (ACC) and are useful for the prevention or treatment of metabolic syndrome, type II diabetes, obesity, atherosclerosis and cardiovascular diseases in humans.
    Type: Application
    Filed: October 27, 2008
    Publication date: February 19, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Robert F. Keyes, Yu Gui Gu, Hing L. Sham
  • Antibacterial compounds
    Patent number: 7196200
    Abstract: Bacterial protein synthesis-inhibiting compounds having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates in the processes, compositions containing the compounds, and methods of using the compounds are disclosed.
    Type: Grant
    Filed: January 21, 2004
    Date of Patent: March 27, 2007
    Assignee: Abbott Laboratories
    Inventors: David D. Anderson, Bruce A. Beutel, Curt S. Cooper, Yu-Gui Gu, Mira M. Hinman, Douglas M. Kalvin, Robert F. Keyes, Xenia B. Searle, Rolf Wagner
  • Thienopyridones as AMPK activators for the treatment of diabetes and obesity
    Patent number: 7119205
    Abstract: The present invention relates to compounds that activate AMP-activated protein kinase (AMPK), including the preparation of the compounds, compositions containing the compounds and the use of the compounds in the prevention or treatment of disorders such as diabetes, metabolic syndrome, and obesity.
    Type: Grant
    Filed: May 17, 2004
    Date of Patent: October 10, 2006
    Assignee: Abbott Laboratories
    Inventors: Rajesh R. Iyengar, Andrew S. Judd, Gang Zhao, Philip R. Kym, Hing L. Sham, Yugui Gu, Gang Liu, Mei Liu, Hongyu Zhao, Richard F. Clark, Ernst U. Frevert, Barbara L. Cool, Tianyuan Zhang, Robert F. Keyes, Todd M. Hansen, Zhili Xin
  • 9a-azalides with antibacterial activity
    Patent number: 6764996
    Abstract: Compounds of formula (I) formula (II) formula (III) and formula (IV) or pharmaceutically acceptable salts or prodrugs thereof, are antibacterial agents. Compositions containing the compounds, processes for making the compounds, synthetic intermediates employed in the processes, and methods for treatment and prevention of bacterial infections are disclosed.
    Type: Grant
    Filed: July 25, 2000
    Date of Patent: July 20, 2004
    Assignee: Abbott Laboratories
    Inventors: Yat Sun Or, Robert F. Keyes, Zhenkun Ma
  • Process for preparing N-demethyl-N-alkyl erythromycin derivatives
    Patent number: 6084079
    Abstract: The claimed invention relates to a novel process of preparing N-demethyl-N-alkyl-4"-deoxy erythromycin A and B. The process comprises protecting the 2'-hydroxy or the 2'- and 11-hydroxy of a N-demethyl-4"-deoxy erythromycin derivative having the formula: ##STR1## where R.sub.b is H or OH, with a silyl protecting group and alkylating the N-position of the desosamine sugar.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: July 4, 2000
    Inventors: Robert F. Keyes, Hemant H. Patel, Ramiya H. Premchandran, Albert V. Thomas, Anne H. Kemp