Patents by Inventor Robert Folberg

Robert Folberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Constricting Gel Assay and Therapeutic Patch
    Publication number: 20080160069
    Abstract: Method and compositions relate diagnostic tools to determine invasive potential of tumor cells. Therapeutic patches include a component from the extracellular matrix seeded with tumor cells from an individual and a fibrin backing. Extracellular matrix-based constriction assays are useful to screen for anti-tumor compounds.
    Type: Application
    Filed: April 11, 2006
    Publication date: July 3, 2008
    Applicant: The Board of Trustees of the University of Illinois
    Inventors: Andrew J. Maniotis, Robert Folberg
  • Methods and compositions related to a matrix chip
    Publication number: 20050142534
    Abstract: Embodiments of the invention relate to devices and methods for evaluating the interactions between cells and between cells and matrix materials wherein the cellular distribution patterns formed as a result of such interactions are indicators of the invasive potential(s) of the cells. Furthermore, such devices and methods can provide indications of the preferred sites of metastasis of invasive cells; the efficacy of an anti-cancer drug applied to such cells; and the potential for agents to promote or enhance tumor growth or metastasis.
    Type: Application
    Filed: October 13, 2004
    Publication date: June 30, 2005
    Inventors: Andrew Maniotis, Robert Folberg
  • Chromosome stability assay
    Publication number: 20050079516
    Abstract: Embodiments of the invention relate to compositions and methods for evaluating or estimating the invasive potential of cells and thereby differentiating between normal and cancerous cells in accordance with the susceptibility of the cellular chromatin to degradation or other modification by particular enzymes or agents. Chromatin within permeabilized normal and non-invasive cells, including chromatin strands removed therefrom, are more susceptible to degradation by endonucleases or proteinases than is the chromatin from invasive cells.
    Type: Application
    Filed: June 7, 2004
    Publication date: April 14, 2005
    Inventors: Andrew Maniotis, Robert Folberg