Abstract: A device for the lithography-based additive manufacturing of three-dimensional structures may comprise a building platform defining a building plane, a light engine designed for the dynamic patterning of light in an exposure field of said light engine, a material transport unit comprising a first drive mechanism for transporting a material layer across the exposure field, a second drive mechanism for causing relative movement of the light engine and the building platform along a displacement path extending parallel to the building plane, a linear encoder for sensing a position and/or a velocity of the light engine relative to the building platform, and/or one or more control units configured to adjust the feeding rate of a pattern data feeder based on the position or the velocity sensed by the linear encoder.

Abstract: Systems, methods, and devices for additive manufacturing are provided. In some embodiments, a method includes: coupling a plurality of build platforms to a carrier; forming a plurality of 3D objects on the plurality of build platforms using an additive manufacturing process, where each build platform receives at least one 3D object thereon; removing the plurality of build platforms from the carrier; performing post-processing of the plurality of 3D objects while the 3D objects remain on the respective build platforms; and separating the plurality of 3D objects from the respective build platforms.

Abstract: A microfluidic device for detection of an analyte in a fluid is described. The microfluidic device comprises a substrate having a first surface defining entrances to one or more chambers defined in the substrate, surfaces of the chambers defining a second surface of the substrate, the first surface being modified for selective targeting and capture of at least one analyte to operably effect a blocking of the entrance to at least one of the chambers, and wherein a response characteristic of the microfluidic device is operably varied by the blocking of the entrance to the at least one of the chambers, thereby providing an indication of the presence of the analyte within the fluid.

Abstract: A microfluidic device for detection of an analyte in a fluid is described. The microfluidic device comprises a substrate having a first surface defining entrances to one or more chambers defined in the substrate, surfaces of the chambers defining a second surface of the substrate, the first surface being modified for selective targeting and capture of at least one analyte to operably effect a blocking of the entrance to at least one of the chambers, and wherein a response characteristic of the microfluidic device is operably varied by the blocking of the entrance to the at least one of the chambers, thereby providing an indication of the presence of the analyte within the fluid.

Abstract: A microfluidic device for detection of an analyte in a fluid is described. The microfluidic device comprises a substrate having a first surface defining entrances to one or more chambers defined in the substrate, surfaces of the chambers defining a second surface of the substrate, the first surface being modified for selective targeting and capture of at least one analyte to operably effect a blocking of the entrance to at least one of the chambers, and wherein a response characteristic of the microfluidic device is operably varied by the blocking of the entrance to the at least one of the chambers, thereby providing an indication of the presence of the analyte within the fluid.

Abstract: Various examples are directed to systems and methods for providing transportation services. A service assignment system may receive a transportation service request from a user. The transportation service request may describe a transportation service having a start location and an end location. The service assignment system may select a first autonomous vehicle (AV) of a first AV type and determine a first predicted route for the first AV using vehicle capability data describing the first AV type and first difference data describing a difference between a previous predicted route for a previous AV of the first AV type and a previous planned route received from the previous AV of the first AV type. The service assignment system may receive, from the first AV, a first planned route for executing the transportation service and instruct the first AV to begin executing the transportation service.

Abstract: Various examples are directed to a service assignment system for providing transportation services. The service assignment system may receive a transportation service request from a user. The transportation service request may describe a transportation service having a service start location and a service end location. The service assignment system may generate a plurality of routes for executing the transportation service. The service assignment system may send proposed route data describing at least a portion of the plurality of routes to a first autonomous vehicle (AV). The service assignment system may receive, from the first AV, route data describing a first route to execute the transportation service and send, to the first AV, instruction data instructing the first AV to begin executing the transportation service.

Abstract: Systems and methods herein describe accessing a set of feature flags, a first feature flag in the set of feature flag describing vehicle navigation behavior on a routing graph, the routing graph representing the roadway, associating the set of feature flags with a vehicle, applying the associated set of feature flags to a graph traversal algorithm to generate a modified graph traversal algorithm, generating the route using the modified graph traversal algorithm; and transmitting instructions to the vehicle to begin executing the route.

Abstract: Various examples are directed to systems and methods for routing autonomous vehicles. A system may receive vehicle capability data describing autonomous vehicles of a first type. The vehicle capability data may comprise geofence data describing a first geographic area. The system may generate first routing graph modification data comprising a first graph element descriptor based at least in part on the first geographic area and a first constraint. The system may access routing graph data describing a plurality of graph elements. The system may generate a first route for an autonomous vehicle of the first type. The generating may be based at least in part on the first routing graph modification data and the routing graph data.

Abstract: A microfluidic device for detection of an analyte in a fluid is described. The microfluidic device comprises a substrate having a first surface defining entrances to one or more chambers defined in the substrate, surfaces of the chambers defining a second surface of the substrate, the first surface being modified for selective targeting and capture of at least one analyte to operably effect a blocking of the entrance to at least one of the chambers, and wherein a response characteristic of the microfluidic device is operably varied by the blocking of the entrance to the at least one of the chambers, thereby providing an indication of the presence of the analyte within the fluid.

Abstract: Various examples are directed to systems and methods for controlling a self-driving vehicle. A computing device may cause the self-driving vehicle to begin traversing a route. The computing device may detect that the self-driving vehicle is approaching an obstruction and determine to take a deviating maneuver to a revised route prior to the obstruction. The computing device may cause the self-driving vehicle to take the deviating maneuver and cause the self-driving vehicle to execute a revised route, the revised route including the deviating maneuver.

Abstract: Various examples are directed to systems and methods for supporting an autonomous vehicle user. A user computing device may send a service arrangement system a service request describing a payload to be transported. The user computing device may receive from the service arrangement system, a service confirmation message describing a stopping location for a user to meet an autonomous vehicle and autonomous vehicle data describing the autonomous vehicle. The user computing device may also receive a first wireless signal from a first wireless beacon and determine a first location of the user computing device using the first wireless signal. The user computing device may display at a display of the user computing device, a direction from the first location of the user computing device to the stopping location.

Abstract: Various examples are directed to systems and methods for routing a plurality of autonomous vehicles. A batch routing system may receive a first general route cost request from a first autonomous vehicle. The first general route cost request may describe a first trip endpoint and a first set of local route endpoints comprising a first local route endpoint and a second local route endpoint. The batch routing system may determine a first set of general routes for the first autonomous vehicle, the first set of general routes comprising a first general route from the first local route endpoint to a first trip endpoint and a second general route from the second local route endpoint to the first trip endpoint. The batch routing system may send a first general route cost reply to the first autonomous vehicle. The first general route cost reply may indicate a first set of costs associated with the first set of general routes.

Abstract: A microfluidic array supporting a lipid bilayer assembly on which membrane proteins can be assembled is described. The array is formed from a hydrophilic polymeric substrate or metal substrate comprising a planar surface with a plurality of individual spherical depressions formed therein. Each of the depressions are configured to have a diameter greater than 1 ?m and containing an aqueous solution. Across each of the depressions is provided a lipid layer. Each of the plurality of individual depressions comprise arcuate side walls extending downwardly into the substrate from the planar surface.

Abstract: Disclosed herein are system, method, and computer program product embodiments for introducing and removing blockchain based cryptocurrency tokens based on usage and demand for the cryptocurrency. An embodiment operates by transmitting, to a peer-to-peer network of computing devices configured to store a blockchain of processes, instructions for execution by one or more devices of the peer-to-peer network. The instructions comprise determining a rate of change associated with an exchange price of a cryptocurrency token. The instructions further include receiving an indication that a first amount of cryptocurrency tokens has been transferred to a recipient address of a plurality of addresses and generating a second amount of cryptocurrency tokens based on the first amount of cryptocurrency tokens that has been transferred and on the determined rate of change of the exchange price associated with the cryptocurrency token. The second amount of cryptocurrency tokens is allocated to the recipient address.

Abstract: A versatile intramedullary nail is constructed in two cooperating and optionally interlocking pieces, with a further optional annular restoration hub. The two cooperating pieces, when interlocked, approximate a long shaft, generally tubular in cross-section, with a recessed area on the male piece adapted to receive the annular restoration hub. The female piece is adapted to receive the flange of the male piece coaxially, and—unless a locking screw or bolt is inserted through the flange—the two pieces can rotate axially. Alternatively, the nail can be constructed of a single solid piece.

Abstract: A versatile intramedullary nail is constructed in two cooperating and optionally interlocking pieces, with a further optional annular restoration hub. The two cooperating pieces, when interlocked, approximate a long shaft, generally tubular in cross-section, with a recessed area on the male piece adapted to receive the annular restoration hub. The female piece is adapted to receive the flange of the male piece coaxially, and—unless a locking screw or bolt is inserted through the flange—the two pieces can rotate axially. Alternatively, the nail can be constructed of a single solid piece.

Abstract: A microfluidic array supporting a lipid bilayer assembly on which membrane proteins can be assembled is described.

Abstract: According to some embodiments, a primary business object BOA is established along with a plurality of secondary business objects that depend from the primary business object BOA in a hierarchy. The primary business object BOA may place a lock on a secondary business object BOB and facilitate an update of data associated with the secondary business object BOB. The secondary business object BOB may then detect when a database commit has been executed, responsive to that detection, the secondary business object BOB may remove the lock associated with the secondary business object BOB.