Patents by Inventor Robert G. Glushkov

Robert G. Glushkov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-[4-(Benzhydrylpiperazinyl-1)butyl]-3-methylxanthine and its salts with organic or inorganic acids possessing antihistaminic and antiallergenic activity
    Patent number: 8569489
    Abstract: The invention relates to a range of original xanthine derivatives substituted in 1 -and 7-positions with benzhydryl-4-piperazinyl-1-alkane fragments. A method for obtaining 3-methyl-7-[4-(benzhydryl-4-piperazinyl-1)butyl]xanthine and the salts thereof with organic and inorganic acids by alkylating the 7-potassium salt of 3-methylxanthine by 1,4-dibromobutane, by subsequently interacting the thus formed 7-(4-bromobutyl)-3-methylxanthine with 1-benzhydrylpiperazinyl and by neutralising the thus obtained radical 7-/4-(4-benzhydrylpiperazinyl-1) butyl/-3-methylxanthine by an organic or inorganic acid is also disclosed.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: October 29, 2013
    Assignee: A.B. Intelpharm Limited
    Inventors: Robert G. Glushkov, Sergei D. Juzhakov, Olga S. Fominova, Nelli M. Sazonova, Elena M. Dolginova, Vadim A. Shorr, Mikhail V. Borovkov, Valentina V. Asnina
  • ANTIHISTAMINIC AND ANTIALLERGIC AGENT AND A METHOD FOR THE PRODUCTION THEREOF
    Publication number: 20100168425
    Abstract: The invention relates to a range of original xanthine derivatives substituted in 1- and 7-positions with benzhydryl-4-piperazinyl-1-alkane fragments. A method for obtaining 3-methyl-7-[4-(benzhydryl-4-piperazinyl-1)butyl]xanthine and the salts thereof with organic and inorganic acids by alkylating the 7-potassium salt of 3-methylxanthine by 1,4-dibromobutane, by subsequently interacting the thus formed 7-(4-bromobutyl)-3-methylxanthine with 1-benzhydrylpiperazinyl and by neutralising the thus obtained radical 7-/4-(4-benzhydrylpiperazinyl-1) butyl/-3-methylxanthine by an organic or inorganic acid is also disclosed.
    Type: Application
    Filed: September 29, 2009
    Publication date: July 1, 2010
    Applicant: OOO 'FARMVING'
    Inventors: Robert G. Glushkov, Sergei D. Juzhakov, Olga S. Fominova, Nelli M. Sazonova, Elena M. Dolginova, Vadim A. Shorr, Mikhail V. Borovkov, Valentina V. Asnina
  • 1-thiocarbamylmethylpyrrolidine-2-thione, process for preparing
    Patent number: 4876360
    Abstract: A novel compound, namely, 1-thiocarbamylmethylpyrrolidine-2-thione has the following formula: ##STR1## A process for preparing said compound comprises reacting a derivative of pyrrolidone-2 of the general formula: ##STR2## wherein R is nitrile or carbamoyl, with phosphorus pentasulphide in an inert non-polar solvent at a temperature above room temperature, followed by treatment of the resulting precipitate with water upon boiling and isolation of the desired product.The compound according to the present invention exhibits antihypoxic and nootropic activity.
    Type: Grant
    Filed: April 5, 1989
    Date of Patent: October 24, 1989
    Inventors: Vladimir G. Granik, Tatyana V. Stezhko, Robert G. Glushkov, Mikhail D. Mashkovsky, Lidia F. Roschina, Antonina I. Polezhaeva, Roza B. Parimbetova, Jury G. Bobkov, Alexandr S. Losev, Irina A. Ivanova
  • 1-Thiocarbamoylmethylpyrrolidine-2-thione, medical compositions of, and anti-hypoxic and nootropic use thereof
    Patent number: 4839380
    Abstract: A novel compound, namely, 1-thiocarbamylmethylpyrrolidine-2-thione has the following formula: ##STR1## A process for preparing said compound comprises reacting a derivative of pyrrolidone-2 of the general formula: ##STR2## wherein R is nitrile or carbamoyl, with phosphorus pentasulphide in an inert non-polar solvent at a temperature above room temperature, followed by treatment of the resulting precipitate with water upon boiling and isolation of the desired product.The compound according to the present invention exhibits antihypoxic and nootropic activity.
    Type: Grant
    Filed: April 4, 1988
    Date of Patent: June 13, 1989
    Inventors: Vladimir G. Granik, Tatyana V. Stezhko, Robert G. Glushkov, Mikhail D. Mashkovsky, Lidia F. Roschina, Antonina I. Polezhaeva, Roza B. Parimbetova, Jury G. Bobkov, Alexandr S. Losev, Irina A. Ivanova
  • Pyrazino (1,2,3-ab)-.beta.-carboline derivatives and salts thereof and method of preparing same
    Patent number: 4088647
    Abstract: New tetracyclic compounds, containing indole nucleus in their structure, having the general formula ##STR1## where R is hydrogen, alkyl, or alkoxyl, R' is an alkyl, and m and n are 2 or 3.The said compounds react with organic and mineral acids to form salts readily soluble in water.The method for preparing the said compounds consists in cyclization of lactams, having the general formula ##STR2## where R, R', m and n are as specified above, or of their hydrochlorides by phosphorus oxychloride.
    Type: Grant
    Filed: December 2, 1976
    Date of Patent: May 9, 1978
    Inventors: Robert G. Glushkov, Mikhail D. Mashkovsky, Nataiia I. Andreeva, Serafima S. Liberman, Leonid N. Gerchikov, Vera A. Volskova, Antonida V. Zaitseva, Onisim J. Magidson, deceased, by Galina K. Magidson, by July O. Magidson, administrators