Abstract: A fluid collection apparatus for use in negative pressure wound therapy. The fluid collection apparatus includes a flexible bag having a first opening and a second opening. The bag includes a structure defining a fluid pathway connecting the first opening and the second opening. The pathway is circulative and contributes to orientation independence of the bag in use. The bag further includes a load-bearing component.

Abstract: Connectors and devices for flexible negative pressure systems are described.

Abstract: A system for delivering an agent to a patient, comprises a delivery device. The delivery device is configured to deliver a first agent to the patient, and comprises a reservoir, a transcutaneous delivery assembly, a pumping mechanism, a control module, a power supply, and a housing. The reservoir stores the first agent. The transcutaneous delivery assembly delivers the first agent to the patient transcutaneously. The pumping mechanism receives the first agent from the reservoir and propels the first agent to the transcutaneous delivery assembly. The control module controls at least the pumping mechanism. The power supply provides energy to at least the control module and the pumping mechanism. The housing surrounds at least the pumping mechanism. Methods of delivering an agent to the patient are also described.

Abstract: Devices and methods for collecting and sensing fluid flow are provided.

Abstract: A fluid collection apparatus for use in negative pressure wound therapy. The fluid collection apparatus includes a flexible bag having a first opening and a second opening. The bag includes a structure defining a fluid pathway connecting the first opening and the second opening. The pathway is circulative and contributes to orientation independence of the bag in use. The bag further includes a load-bearing component.

Abstract: A unit dose container for holding a single dose of a given liquid, the container comprising: a chamber (8) in which, in use, the given liquid is stored, the chamber having a wall through which, in use, the liquid is to be supplied; a release mechanism (7), at least part of which is internal to, or forms part of the wall of the chamber, the release mechanism being movable relative to the chamber between first and second positions; and means for allowing the release mechanism (7) to move from the first to the second positions, thereby opening a passage through the wall so that the liquid can exit the chamber (8), the means including at least one flexible wall portion.

Abstract: A fluid collection apparatus for use in negative pressure wound therapy. The fluid collection apparatus includes a flexible bag having a first opening and a second opening. The bag includes a structure defining a fluid pathway connecting the first opening and the second opening. The pathway is circulative and contributes to orientation independence of the bag in use. The bag further includes a load-bearing component.

Abstract: A liquid droplet production apparatus comprising a perforate membrane and an actuator. The actuator is configured to vibrate the perforate membrane such that a liquid in contact with the perforate membrane during use is caused to pass through at least one aperture of the perforate membrane and to be ejected as liquid droplets from the perforate membrane. The perforate membrane includes one or more stiffening structures for increasing the stiffness of the perforate membrane, the one or more stiffening structures each being defined by a local transverse deformation of the perforate membrane. A removable cartridge, a perforate membrane, an actuator assembly for use in such a liquid droplet delivery apparatus, and a method of manufacturing a perforate membrane for such a liquid droplet apparatus.

Abstract: A cartridge for an aerosol delivery system. The cartridge includes a fluid reservoir including a first reservoir portion, a second reservoir portion, and at least one liquid barrier configured to separate the first and second reservoir portions. The first and second reservoir portions have respective first and second openings at a first end of the cartridge. The cartridge further includes a perforate membrane located at the first end of the cartridge and over the first and second openings. The first and second openings are configured to supply first and second liquids to a first side of the perforate membrane during use and the perforate membrane comprises a plurality of apertures configured to eject one or both of the first and second liquids from a second side of the perforate membrane in the form of liquid droplets when the perforate membrane is vibrated. An aerosol delivery system includes the cartridge.

Abstract: A micro-nozzle with an integrated filter structure for receiving fluids at pressures between 0.1 MPa to 50 MPa, comprising: at least one fluid inlet, a fluid outlet comprising at least one orifice, a primary filter structure positioned downstream from the at least one fluid inlet and arranged to provide statistical filtration of fluid passing therethrough.

Abstract: An aerosol delivery system includes a perforate membrane comprising a plurality of apertures, as well as a fluid reservoir reservoir in fluid communication with a first side of the perforate membrane and actuation means configured to vibrate the perforate membrane to cause a liquid in the fluid reservoir during use to be ejected as liquid droplets from a second side of the perforate membrane. The plurality of apertures comprises first and second arrays of apertures of first and second configurations which are grouped together in first and second discrete regions of the perforate membrane. The fluid reservoir includes first and second reservoir portions and a liquid barrier by which the first and second reservoir portions are separated. A removable cartridge for an aerosol delivery system.

Abstract: An apparatus is provided for nebulising a liquid from a liquid supply through a membrane comprising first and second surfaces and a plurality of apertures extending through the membrane. The apparatus comprises an area for receiving a liquid supply, arranged to deliver a liquid to the first surface of the membrane, a vibrator member, arranged to vibrate the membrane to eject liquid droplets from the front surface of the membrane on vibration; and a mechanical coupling means, arranged to provide a removable mechanical clamping force for clamping the membrane to the vibrator member. Various means for implementing the mechanical coupling are provided, and liquid containers and membranes for use in the device are proposed.

Abstract: Fluid collection apparatuses and methods of use in negative pressure therapies are provided.

Abstract: There is disclosed a device for delivering a fluid spray to a mouth of a user, either directly, or via a flow conductor such as a tube or pipe. The spray device uses a vibrating perforate membrane to create the spray and the vibration of the membrane is controlled in response to input from a flow rate sensor which detects a flow rate through the device or through the flow conductor. There is further disclosed a corresponding method of controlling a spray head in a spray delivery device.

Abstract: Fluid collection apparatuses and methods of use in negative pressure therapies.

Abstract: An apparatus is provided for nebulising a liquid from a liquid supply through a membrane comprising first and second surfaces and a plurality of apertures extending through the membrane. The apparatus comprises an area for receiving a liquid supply, arranged to deliver a liquid to the first surface of the membrane, a vibrator member, arranged to vibrate the membrane to eject liquid droplets from the front surface of the membrane on vibration; and a mechanical coupling means, arranged to provide a removable mechanical clamping force for clamping the membrane to the vibrator member. Various means for implementing the mechanical coupling are provided, and liquid containers and membranes for use in the device are proposed.

Abstract: Connectors and devices for flexible negative pressure systems are described.

Abstract: Devices and methods for collecting and sensing fluid flow are provided.

Abstract: A liquid droplet production apparatus includes a perforate membrane, with liquid being supplied to one side of the membrane. An actuator for vibrating the membrane is provided. The vibration causes liquid droplets to be ejected from the other side of the membrane. Magnetic force is used to connect the actuator to the membrane so that the vibration can be transmitted.

Abstract: An apparatus is provided for nebulizing a liquid from a liquid supply through a membrane comprising first and second surfaces and a plurality of apertures extending through the membrane. The apparatus includes an area for receiving a liquid supply, arranged to deliver a liquid to the first surface of the membrane, a vibrator member, arranged to vibrate the membrane to eject liquid droplets from the front surface of the membrane on vibration; and a mechanical coupling mechanism, arranged to provide a removable mechanical clamping force for clamping the membrane to the vibrator member. Various mechanisms for implementing the mechanical coupling are provided, and liquid containers and membranes for use in the device are proposed.