Patents by Inventor Robert H. Reid
Robert H. Reid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11980767Abstract: A medical device management system comprising a defibrillating apparatus, which comprises a plurality of electrodes configured to monitor ECG signals and deliver a defibrillation shock. The system including a communication unit configured to establish a secured wireless network, automatically generate a first text message upon receipt of a signal indicative of deployment of the defibrillating apparatus, associate the first text message with a unit identifier, automatically send the first text message, automatically generate a second text message comprising defibrillation shock status upon delivery of the defibrillation shock, associate the second text message with the unit identifier, automatically send the second text message; and a handheld device associated with a caregiver and configured to receive the first and second text messages and associate the first and second text messages with the specific defibrillating apparatus based on the unit identifier specific to the defibrillating apparatus.Type: GrantFiled: December 4, 2018Date of Patent: May 14, 2024Assignee: ZOLL Medical CorporationInventors: Ziad F Elghazzawi, C. Shane Reid, Andrew D Funk, Robert H Gotschall, Charles E Sawyer, Jr., Melissa M Dascoli
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Publication number: 20100074913Abstract: This invention is directed to oral-intestinal vaccines and their use against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres.Type: ApplicationFiled: September 15, 2009Publication date: March 25, 2010Inventors: Edgar C. Boedeker, Frederick J. Cassels, Daniel L. Jarboe, Robert H. Reid
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Patent number: 7604811Abstract: This invention is directed to oral-intestinal vaccines and their use against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres.Type: GrantFiled: December 10, 1996Date of Patent: October 20, 2009Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Daniel L. Jarboe, Robert H. Reid, Edgar C. Boedeker, Frederick J. Cassels
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Patent number: 7033608Abstract: Novel burst-free, sustained release biocompatible and biodegrable microcapsules which can be programmed to release their active core for variable durations ranging from 1–100 days in an aqueous physiological environment. The microcapsules are comprised of a core of polypeptide or other biologically active agent encapsulated in a matrix of poly(lactide/glycolide) copolymer as a blend of uncapped (free carboxyl end group) and end-capped forms ranging in ratios from 100/0 to 1/99.Type: GrantFiled: June 22, 1999Date of Patent: April 25, 2006Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Ramasubbu Jevanthi, John E. Van Hamont, Phil Friden, Robert H. Reid, F. Donald Roberts, Charles E. McQueen, Jean A. Setterstrom
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Patent number: 6902743Abstract: Novel burst-free, sustained release biocompatible and biodegrable microcapsules which can be programmed to release their active core for variable durations ranging from 1-100 days in an aqueous physiological environment. The microcapsules are comprised of a core of polypeptide or other biologically active agent encapsulated in a matrix of poly(lactide/glycolide) copolymer having a molar composition of lactide/glycolide from 90/10 to 40/60, which may contain a pharmaceutically-acceptable adjuvant, as a blend of uncapped free carboxyl end group and end-capped forms ranging to ratios from 100/0 to 1/99.Type: GrantFiled: April 6, 1998Date of Patent: June 7, 2005Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Jean A. Setterstrom, Thomas R. Tice, Elliot Jacob, Robert H. Reid, John van Hamont, Edgar C. Boedecker, Ramassubbu Jeyanthi, Phil Friden, F. Donald Roberts, Charles E. McQueen, Apurba Bhattacharjee, Alan Cross, Jerald Sadoff, Wendell Zollinger
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Patent number: 6844010Abstract: Novel burst-free, sustained release biocompatible and biodegrable microcapsules which can be programmed to release their active core for variable durations ranging from 1-100 days in an aqueous physiological environment. The microcapsules are comprised of a core of polypeptide or other biologically active agent encapsulated in a matrix of poly(lactide/glycolide) copolymer, which may contain a pharmaceutically-acceptable adjuvant, as a blend of upcapped free carboxyl end group, and end-capped forms ranging in ratios from 100/0 to 1/99.Type: GrantFiled: July 18, 2000Date of Patent: January 18, 2005Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Jean A. Setterstrom, John E. Van Hamont, Robert H. Reid, Elliot Jacob, Ramasubbu Jeyanthi, Edgar C. Boedeker, Charles E. McQueen, Daniel L. Jarboe, Frederick Cassels, William Brown, Curt Thies, Thomas R. Tice, F. Donald Roberts, Phil Friden
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Publication number: 20030161889Abstract: This invention relates to an immunostimulating composition comprising encapsulating microspheres, which may contain a pharmaceutically-acceptable adjuvant, wherein said microspheres having a diameter between 1 nanometer (nm) to 10 microns (um) are comprised of (a) a biodegradable-biocompatible poly(DL-lactide-co-glycolide) as the bulk matrix, wherein the relative ratio between the amount of lactide and glycolide components are within the range of 40:60 to 0:100 and wherein said poly (DL-lactide-co-glycolide) is present in an uncapped form and an end-capped form wherin a ratio of uncapped to end-capped forms is 99/1 to 1/99, and (b) an immunogenic substance comprising Colony Factor Antigen (CFA/II), hepatitis B surface antigen (HbsAg), or a physiologically similar antigen that serves to elicit the producton of antibodies in animal subjects. The preparation of its composition and its use as a vaccine is also disclosed.Type: ApplicationFiled: August 20, 2002Publication date: August 28, 2003Inventors: Robert H. Reid, Jean A. Setterstrom, Edgar Boedeker, John VanHamont, Charles McQueen, Frederick Cassels
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Publication number: 20030082193Abstract: Assay methods for determining whether a peptide is likely to be immunogenic are based on a computer modeling of binding to a Class II MHC DR1 receptor. This is confirmed by competitive inhibition binding assays. The peptides are useful for eliciting an immune response for vaccination or the production of antibodies or T-cells.Type: ApplicationFiled: January 26, 1998Publication date: May 1, 2003Inventors: JEFFREY L. NAUSS, ROBERT H. REID, MARCIA WOLF, Scheherazade Sadegh-Nasseri
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Patent number: 6346392Abstract: The invention provides Glutamine Transport ATP-Binding Protein polypeptides and DNA (RNA) encoding Glutamine Transport ATP-Binding Protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Glutamine Transport ATP-Binding Protein polypeptides to screen for antibacterial compounds.Type: GrantFiled: July 10, 1997Date of Patent: February 12, 2002Assignees: SmithKline Beecham Corporation, SmithKline Beecham PLCInventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard O Nicholas, Martin Karl Russel Burnham, Robert H Reid, Jr., Phillip N Zarfos
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Patent number: 6309669Abstract: Novel burst-free, sustained release biocompatible and biodegrable microcapsules which can be programmed to release their active core for variable durations ranging from 1-100 days in an aqueous physiological environment. The microcapsules are comprised of a core of polypeptide or other biologically active agent encapsulated in a matrix of poly(lactide/glycolide) copolymer, which may contain a pharmaceutically-acceptable adjuvant, as a blend of upcapped free carboxyl end group and end-capped forms ranging in ratios from 100/0 to 1/99.Type: GrantFiled: January 27, 1997Date of Patent: October 30, 2001Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Jean A. Setterstrom, John E. Van Hamont, Robert H. Reid, Elliot Jacob, Ramasubbu Jeyanthi, Edgar C. Boedeker, Charles E. McQueen, Daniel L. Jarboe, Frederick Cassels, William Brown, Curt Thies, Thomas R. Tice, F. Donald Roberts, Phil Friden
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Patent number: 6287803Abstract: The invention provides era polypeptides and DNA (RNA) encoding era polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing era polypeptides to screen for antibacterial compounds.Type: GrantFiled: November 6, 1997Date of Patent: September 11, 2001Assignees: SmithKline Beecham Corporation, SmithKline Beecham plcInventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard Oakley Nicholas, Leslie Marie Palmer, Robert H. Reid, Martin Rosenberg, Phillip Zarfos
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Patent number: 6165989Abstract: The invention provides era polypeptides and DNA (RNA) encoding era polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing era polypeptides to screen for antibacterial compounds.Type: GrantFiled: September 22, 1997Date of Patent: December 26, 2000Assignee: SmithKline Beecham CorporationInventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Michael Arthur Lonetto, Richard O Nicholas, Martin Karl Russel Burnham, Robert H Reid, Jr., Robert King Stodola, Phillip N Zarfos
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Patent number: 5762965Abstract: This invention relates to parenteral and mucosal vaccines against diseases aused by intracellular pathogens using antigens encapsulated within a biodegradable-biocompatible microspheres(matrix).Type: GrantFiled: February 9, 1996Date of Patent: June 9, 1998Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Paul R. Burnett, John E. Van Hamont, Robert H. Reid, Jean A. Setterstrom, Thomas C. Van Cott, Debrah L. Birx
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Patent number: 5705197Abstract: A hybrid evaporation-extraction process for preparing microspheres of a p(DL-lactide-to-glycolide) biodegradable polymer, comprising:a. preparing a lyophilized biologically active material-sucrose matrix; adding acetonitrile solvent to biologically active material-sucrose matrix to form a solution;b. preparing a solution of a biodegradable poly (DL-lactide-co-glycolide) polymer by adding acetonitrile solvent to the polymer;c. adding the biodegradable poly (DL-lactide-co-glycolide) polymer acetonitrile solution to the biologically active material-sucrose acetonitrile solution;d. adding with stirring an oil containing lecithin to the poly (DL-lactide-co-glycolide) polymer-sucrose-biologically active material solution to evaporate acetonitrile and form an emulsion containing microspheres of poly (DL-lactide-co-glycolide) biodegradable polymers;e. adding the emulsion from step d. into a solvent selected from heptane, hexane, pentane or isopropanol; andf.Type: GrantFiled: August 16, 1996Date of Patent: January 6, 1998Assignee: The United States of America as represented by the Secretary of the ArmyInventors: John Van Hamont, Curt Thies, Robert H. Reid, Charles E. McQueen, Jean A. Setterstrom
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Patent number: 5693343Abstract: In a solvent extraction process for preparing microspheres of a biodegrade polymer, the improvement comprising: preparing a homogenized antigen-sucrose matrix and adding a solvent to the sucrose-antigen matrix to form a solution; preparing a solution of a biodegradable polymer by adding a solvent to the polymer; adding the biodegradable polymer solution to the antigen-sucrose solution; adding an oil to the polymer-sucrose-antigen solution to form an emulsion having a controlled viscosity that corresponds to a predetermined average particle size of distributions of microspheres of biodegradable polymers; centrifuging the emulsion of controlled viscosity and removing the supernatant to obtain microspheres of a predetermined range of particle size distributions of from about 0.5 to about 7.0 micrometers.Type: GrantFiled: May 16, 1994Date of Patent: December 2, 1997Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Robert H. Reid, John E. van Hamont, William R. Brown, Egar C. Boedeker, Curt Thies
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Patent number: 5417986Abstract: This invention is directed to oral parenteral and intestinal vaccines and eir use against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres.Type: GrantFiled: April 10, 1992Date of Patent: May 23, 1995Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Robert H. Reid, Edgar C. Boedeker, John E. van Hamont, Jean A. Setterstrom
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Patent number: 4174385Abstract: It has now been determined that cancer cells have a specific surface protein existing as a glycoprotein which functions to stimulate specific cell-mediated immune response in the host directed toward the specific cancer. The following disclosure includes the method of identification of the specific cell surface protein and procedures utilizing the protein, or preferably the active peptide in testing for specific cancers and immunization. Having identified the specific cell surface protein for a cancer, the n-terminal tridecapeptide or the active portion of the peptide may be synthesized and utilized in testing and immunization. Further, the specific cell surface protein and active peptide for ductal carcinoma (brest cancer) is identified herein.Type: GrantFiled: October 8, 1976Date of Patent: November 13, 1979Assignees: Robert Reid, Robert Alpern, Allan B. Schmier, Sheldon A. Fealk, Jerry Michael EllisInventor: Robert H. Reid
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Patent number: 3955304Abstract: A fishing lure exhibiting a combined traversing action and spray inducing surfing has a streamlined body with a flat top and a trailing flexible skirt. The body is diamond shaped in one cross-section and has a leader receiving aperture extending longitudinally therethrough. A long cylindrical weight is positioned symmetrically between the body sides and eccentrically between the flat top and leader receiving aperture.Type: GrantFiled: July 28, 1975Date of Patent: May 11, 1976Inventor: Robert H. Reid
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Patent number: RE40786Abstract: This invention relates to parenteral and mucosal vaccines against diseases caused by intercellular pathogens using antigens encapsulated within a biodegradable-biocompatible microspheres(matrix).Type: GrantFiled: June 2, 2000Date of Patent: June 23, 2009Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Paul R. Burnett, John E. van Hamont, Robert H. Reid, Jean A. Setterstrom, Thomas C. Van Cott, Deborah L. Birx
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Patent number: RE41157Abstract: In a solvent extraction process for preparing microspheres of a biodegradable polymer, the improvement comprising: preparing a homogenized antigen-sucrose matrix and adding a solvent to the sucrose-antigen matrix to form a solution; preparing a solution of a biodegradable polymer by adding a solvent to the polymer; adding the biodegradable polymer solution to the antigen-sucrose solution; adding an oil to the polymer-sucrose-antigen solution to form an emulsion having a controlled viscosity that corresponds to a predetermined average particle size of distributions of microspheres of biodegradable polymers; centrifuging the emulsion of controlled viscosity and removing the supernatant to obtain microspheres of a predetermined range of particle size distributions of from about 0.5 to about 7.0 micrometers.Type: GrantFiled: November 30, 1999Date of Patent: March 2, 2010Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Robert H. Reid, John E. VanHamont, William R. Brown, Edgar C. Boedeker, Curt Thies