Abstract: Systems and methods for determining when a fluid supply container of a blood processing apparatus becomes empty. The system uses a scale to monitor and detect when a fluid supply container is empty based on the rate of change of the container weight, and a controller receives a signal from the scale and controls the operation of a pump to stop pumping when the fluid supply container is empty.

Abstract: Systems and methods for controlling fluid flow during a fluid exchange procedure. In one aspect, a system is provided for controlling a net fluid volume difference of a patient during and/or after a fluid exchange procedure. The system comprises a first flow path for flowing at least a first fluid from the patient and a second flow path for flowing at least a second fluid to the patient. First and second reservoirs are respectively associated with the first and second flow paths. A controller is associated with the first and second flow paths for controlling first and second flow rates and operable to determine an actual flow rate for each first and second fluid and to change a first or second flow rate in response to a difference between at least one of such flow rates and its respective actual flow rate.

Abstract: Systems and methods for determining when a fluid supply container of a blood processing apparatus becomes empty. The system uses a scale to monitor and detect when a fluid supply container is empty based on the rate of change of the container weight, and a controller receives a signal from the scale and controls the operation of a pump to stop pumping when the fluid supply container is empty.

Abstract: Systems and methods for determining when a fluid supply container of a blood processing apparatus becomes empty. The system uses a scale to monitor and detect when a fluid supply container is empty based on the rate of change of the container weight, and a controller receives a signal from the scale and controls the operation of a pump to stop pumping when the fluid supply container is empty.

Abstract: Blood processing systems and methods rotate a processing chamber on a rotating element. The processing chamber includes a first compartment and a second compartment. Blood is conveyed into the first compartment for centrifugal separation into components. A liquid free of blood occupies the second compartment to counter-balance the first compartment during rotation on the rotating element. In one embodiment, the second compartment is served by a single fluid flow access. Prior to use, the single access is coupled to tubing, through which a vacuum is drawn to remove air from the second compartment. While the vacuum exists, communication is opened between the tubing and a source of liquid. The vacuum draws the liquid into the second compartment through the single access, thereby priming the second compartment for use.

Abstract: Blood processing systems and methods rotate a processing chamber on a rotating element. The processing chamber includes a first compartment and a second compartment. Blood is conveyed into the first compartment for centrifugal separation into components. A liquid free of blood occupies the second compartment to counter-balance the first compartment during rotation on the rotating element. In one embodiment, the second compartment is served by a single fluid flow access. Prior to use, the single access is coupled to tubing, through which a vacuum is drawn to remove air from the second compartment. While the vacuum exists, communication is opened between the tubing and a source of liquid. The vacuum draws the liquid into the second compartment through the single access, thereby priming the second compartment for use.

Abstract: Fluid processing systems and methods make use of a replenishable source containing a volume of a processing fluid that is dispensed during a processing period. A processor serves to sequentially pause and resume the processing period. The processor records weight values of the source at commencement of the processing period; upon pauses in the processing period; and upon resumptions of the processing period. At termination of the processing period, the processor generates a total volume value of processing fluid dispensed from the source during the processing period, which takes into account replenishment of the processing fluid when the processing period is paused. The systems and methods can be integrated into blood processing circuits to monitor the introduction of anticoagulant.

Abstract: Blood processing systems and methods rotate a processing chamber on a rotating element. The processing chamber includes a first compartment and a second compartment. Blood is conveyed into the first compartment for centrifugal separation into components. A liquid free of blood occupies the second compartment to counter-balance the first compartment during rotation on the rotating element. In one embodiment, the second compartment is served by a single fluid flow access. Prior to use, the single access is coupled to tubing, through which a vacuum is drawn to remove air from the second compartment. While the vacuum exists, communication is opened between the tubing and a source of liquid. The vacuum draws the liquid into the second compartment through the single access, thereby priming the second compartment for use.

Abstract: Systems and methods rotate a chamber, in which whole blood is centrifugally separated into packed red blood cells, a plasma constituent, and an interface between the packed red blood cells and the plasma constituent. The interface carries platelets and mononuclear cells. The systems and methods include an interface control unit. The interface control unit is operative in a first state to enable removal of platelet-poor plasma in a first container for use as a diluting liquid. In a second state, the interface control unit retains mononuclear cells in the chamber, while removing platelet-rich plasma from the chamber, bypassing the platelet-poor collection container, thereby maintaining its platelet-poor character. In a third state, the interface control unit enables the removal of mononuclear cells from the chamber in a path that leads to a second container, where the mononuclear cells are collected.

Abstract: Blood processing systems and methods rotate a processing chamber on a rotating element. The processing chamber includes a first compartment and a second compartment. Blood is conveyed into the first compartment for centrifugal separation into components. A liquid free of blood occupies the second compartment to counter-balance the first compartment during rotation on the rotating element. In one embodiment, the second compartment is served by a single fluid flow access. Prior to use, the single access is coupled to tubing, through which a vacuum is drawn to remove air from the second compartment. While the vacuum exists, communication is opened between the tubing and a source of liquid. The vacuum draws the liquid into the second compartment through the single access, thereby priming the second compartment for use.

Abstract: A blood separation system operates in a first mode to convey whole blood into the inlet region of a blood processing chamber for centrifugal separation into packed red blood cells, a plasma constituent, and an interface, which carries mononuclear cells, between the packed red blood cells and the plasma constituent. The system removes packed red blood cells and the plasma constituent from the chamber, while maintaining the interface within the chamber. The system operates in a second mode to remove the interface from the chamber by conveying packed red blood cells into the inlet region. An outlet path conveys the removed interface from the chamber. The outlet path includes a first sensing element to locate mononuclear cells in the removed interface and provide a sensed output upon locating mononuclear cells.

Abstract: Blood separation systems and methods employ a rotating chamber. The chamber includes an inlet region where whole blood enters for centrifugal separation into packed red blood cells, a plasma constituent, and an interface carrying mononuclear cells between the packed red blood cells and the plasma constituent. The packed red blood cells in the chamber have a hematocrit value H.sub.PRBC. A controller operates in a first mode to convey whole blood into the inlet region while removing packed red blood cells and the plasma constituent from the chamber and while maintaining the interface within the chamber. The controller also operates in the first mode to maintain a set H.sub.PRBC by conveying packed red blood cells into the inlet region.