Abstract: Diffraction grating based fiber optic interferometric systems for use in optical coherence tomography, wherein sample and reference light beams are formed by a first beam splitter and the sample light beam received from a sample and a reference light beam are combined on a second beam splitter. In one embodiment, the first beam splitter is an approximately 50/50 beam splitter, and the second beam splitter is a non 50/50 beam splitter. More than half of the energy of the sample light beam is directed into the combined beam and less than half of the energy of the reference light beam are directed into the combined beam by the second beam splitter. In another embodiment, the first beam splitter is a non 50/50 beam splitter and the second beam splitter is an approximately 50/50 beam splitter. An optical circulator is provided to enable the sample light beam to bypass the first beam splitter after interaction with a sample.

Abstract: A medical device and system capable of providing on-demand delivery of biologically active material to a body lumen patient, and a method of making such medical device. A first coating layer comprising a biologically active material and optionally a polymeric material is disposed on the surface of the medical device. A second coating layer comprising magnetic particles and a polymeric material is disposed on the first coating layer. The second coating layer, which is substantially free of a biologically active material, protects the biologically active material prior to delivery. The system includes the medical device and a source of energy, such as an electromagnetic or mechanical vibrational energy. When the patient is exposed to the energy source, the magnetic particles move out of the second coating layer and create channels therein through which the biologically active material can be released.

Abstract: A medical device for creating images of tissue within a body includes a disposable liquid-confining sheath supporting an elongate flexible drive shaft which carries an imaging device such as a ultrasound transducer. The device may include a trocar adapted to receive the sheath, the trocar permitting the device to be inserted into the body where no natural passageway exists, the trocar having a side-facing region adapted to maintain registry with the imaging device while the imaging device rotates. In another embodiment, the drive shaft includes an outer coil that is configured such that when the drive shaft is driven in the direction tending to decrease the diameter of the outer coil, the outer surface of the outer coil pressurizes liquid distally of the outer surface. The device optionally includes an inflatable balloon.

Abstract: Diffraction grating based fiber optic interferometric systems for use in optical coherence tomography, wherein sample and reference light beams are formed by a first beam splitter and the sample light beam received from a sample and a reference light beam are combined on a second beam splitter. In one embodiment, the first beam splitter is an approximately 50/50 beam splitter, and the second beam splitter is a non 50/50 beam splitter. More than half of the energy of the sample light beam is directed into the combined beam and less than half of the energy of the reference light beam are directed into the combined beam by the second beam splitter. In another embodiment, the first beam splitter is a non 50/50 beam splitter and the second beam splitter is an approximately 50/50 beam splitter. An optical circulator is provided to enable the sample light beam to bypass the first beam splitter after interaction with a sample.

Abstract: A large area thermal ablation apparatus for use with an endoscope includes a housing and at least one electrode. The housing is removably attachable to a distal terminating end of the endoscope. The housing includes an outer surface and a cross-sectional area that is at least as large as a cross-sectional area of the distal terminating end of the endoscope. The electrode is supported by the outer surface of the housing. The electrode is capable of delivering energy to a tissue region inside a body to ablate the tissue region.

Abstract: A method of providing wireless communication to a personal communication device in an rf restricted environment. The personal communication device has a radiative antenna. The method comprising: providing a personal communication device with a radiative antenna; providing a first coupler antenna within the rf restricted environment; connecting the first coupler antenna to a second antenna mounted on the outside of the rf restricted environment through a computer controlled circuit arranged therebetween; wirelessly connecting the first coupler antenna with the radiative antenna of the personal communication device within the rf restricted environment; monitoring communications of the personal communication device at any point between the first coupler antenna and the second antenna; and billing for use of the personal communication device within the rf restricted environment. The personal communication device may be a cellular telephone. The personal communication device may be a laptop computer.

Abstract: A display is located on an interventional device insertible into a body. More specifically, the display is located on a distal end of the device and is coupled to a sensing system. The sensing system senses a bodily condition. The display receives the sensed bodily condition and displays a signal indicative of the bodily condition within a pre-existing field of view.

Abstract: An imaging system comprises an interferometer and an ultrasound console that processes signals from the interferometer into an image for display. The interferometer may include one or more multi-element photo detectors with a plurality of parallel outputs. A parallel to serial converter is provided between the parallel output of the interferometer and the input of the ultrasound console, to convert the signals provided on the parallel outputs into a serial signal for analysis by the ultrasound console. The interferometer may be selectively coupled to the ultrasound console and the system may further comprise an ultrasound device that may also be selectively coupled to the console, offering a user the option of using either the interferometer or the ultrasound device. The ultrasound console may also include two inputs, one for the interferometer and the other for the ultrasound device.

Abstract: A medical system includes a catheter having an elongated tubular member and an inner core slideably received within the elongated member. The inner core includes an imager on a distal end and is coupled with a control system and an imaging system. The inner core is configured to scan the interior of a lumen by radially rotating around a center axis and axially translating along the center axis while within the elongated member. The medical system is configured to dynamically image a body lumen at a high speed in order to allow for optical imaging in a safe manner without long durations of blood sequestration and displacement. The medical system is configured to obtain three dimensional images of the body lumen with as little as one dimensional scanning of the lumen. Images of the lumen can be stored and viewed at a desired rate after scanning.

Abstract: An optical catheter connection system is described which has two mating assemblies: a motor unit and an optical catheter connector. The optical catheter connector mates to the motor unit for coupling optical signal into and out of a catheter optical fiber and providing drive torque to the catheter optical fiber. The motor unit includes a rotary shaft powered by a motor for providing drive torque to the catheter optical fiber to rotate the fiber. The motor unit further includes a split sleeve for aligning a motor optical fiber with the catheter optical fiber for coupling optical signals between the two fibers. In one embodiment, a shield is provided around the outer surface of the optical catheter connector to help maintain a sterile field by forming a barrier between a clinician's sterile hand, which holds the optical catheter connector, and the non-sterile motor unit.

Abstract: A thermal acoustic system is a medical imaging device, such as a catheter, adapted to measure the temperature of portions of a lumen of a living being. In one embodiment, the catheter includes a transducer configured to receive a thermally generated acoustic wave when located within the lumen and output a first signal corresponding to the intensity of the received thermally generated acoustic wave. In one embodiment, the thermal acoustic system also displays a temperature measurement, or relative temperatures, of the lumen mapped onto an image of the topology of the lumen. The catheter can further include an elongated, tubular member configured to allow the transducer to move within the elongated member and a control system configured to move the transducer such that it can radially and axially scan the temperature of the lumen.

Abstract: An optical catheter connection system is described which has two mating assemblies: a motor unit and an optical catheter connector. The optical catheter connector mates to the motor unit for coupling optical signal into and out of a catheter optical fiber and providing drive torque to the catheter optical fiber. The motor unit includes a rotary shaft powered by a motor for providing drive torque to the catheter optical fiber to rotate the fiber. The motor unit further includes a split sleeve for aligning a motor optical fiber with the catheter optical fiber for coupling optical signals between the two fibers. In one embodiment, a shield is provided around the outer surface of the optical catheter connector to help maintain a sterile field by forming a barrier between a clinician's sterile hand, which holds the optical catheter connector, and the non-sterile motor unit.

Abstract: A medical device and system capable of providing on-demand delivery of biologically active material to a body lumen patient, and a method of making such medical device. A first coating layer comprising a biologically active material and optionally a polymeric material is disposed on the surface of the medical device. A second coating layer comprising magnetic particles and a polymeric material is disposed on the first coating layer. The second coating layer, which is substantially free of a biologically active material, protects the biologically active material prior to delivery. The system includes the medical device and a source of energy, such as an electromagnetic or mechanical vibrational energy. When the patient is exposed to the energy source, the magnetic particles move out of the second coating layer and create channels therein through which the biologically active material can be released.

Abstract: The present invention comprises a docking system for connecting a portable communication device to a further signal transmission line. The docking system may be arranged within a workstation such as a desk or a tray. The system may also envelope a room in a building or be located in a vehicle, to control and restrict the radiative emission from the communication device and to direct such radiation to a further remote antenna and or signal distribution system connected to the transmission line.

Abstract: A medical device for creating images of tissue within a body includes a disposable liquid-confining sheath supporting an elongate flexible drive shaft which carries an imaging device such as a ultrasound transducer. The device may include a trocar adapted to receive the sheath, the trocar permitting the device to be inserted into the body where no natural passageway exists, the trocar having a side-facing region adapted to maintain registry with the imaging device while the imaging device rotates. In another embodiment, the drive shaft includes an outer coil that is configured such that when the drive shaft is driven in the direction tending to decrease the diameter of the outer coil, the outer surface of the outer coil pressurizes liquid distally of the outer surface. The device optionally includes an inflatable balloon.

Abstract: A medical device vibratory activation system is disclosed. The system includes an implantable appliance comprising a conductive material and a signal producing mechanism having a portion configured to be located relative to the implantable appliance. The signal-producing mechanism is also configured to generate a signal that interacts with the conductive material in the implantable appliance to induce a motion of the implantable appliance.

Abstract: The present invention comprises a docking system for connecting a portable communication device to a further signal transmission line. The docking system may be arranged within a workstation such as a desk or a tray. The system may also envelope a room in a building or be located in a vehicle, to control and restrict the radiative emission from the communication device and to direct such radiation to a further remote antenna and or signal distribution system connected to the transmission line.

Abstract: In one embodiment, the invention provides an imaging device having a light source, a photo-sensor and a scanning assembly. In some embodiments, the light source is fixedly mounted in the first end of an elongated sheath and is adapted for illuminating a target, and the photo-sensor is mounted on the scanning assembly, also in the first end of the elongated sheath, and is adapted to detect light energy from the target. In other embodiments, the light source is movably mounted and the detector is held stationary. In other embodiments, both the light source and the photo-sensor are movably mounted. The scanning devices synchronously capture light energy from each of a plurality locations on the target, the light energy resulting from illumination by the light source, and synchronously digitizes the output from the photo-sensor from each of the plurality of locations on the target to generate an image of the target.

Abstract: A medical device for creating images of tissue within a body includes a disposable liquid-confining sheath supporting an elongate flexible drive shaft which carries an imaging device such as a ultrasound transducer. The device may include a trocar adapted to receive the sheath, the trocar permitting the device to be inserted into the body where no natural passageway exists, the trocar having a side-facing region adapted to maintain registry with the imaging device while the imaging device rotates. In another embodiment, the drive shaft includes an outer coil that is configured such that when the drive shaft is driven in the direction tending to decrease the diameter of the outer coil, the outer surface of the outer coil pressurizes liquid distally of the outer surface. The device optionally includes an inflatable balloon.

Abstract: A medical device for creating images of tissue within a body includes a disposable liquid-confining sheath supporting an elongate flexible drive shaft which carries an imaging device such as a ultrasound transducer. The device may include a trocar adapted to receive the sheath, the trocar permitting the device to be inserted into the body where no natural passageway exists, the trocar having a side-facing region adapted to maintain registry with the imaging device while the imaging device rotates. In another embodiment, the drive shaft includes an outer coil that is configured such that when the drive shaft is driven in the direction tending to decrease the diameter of the outer coil, the outer surface of the outer coil pressurizes liquid distally of the outer surface. The device optionally includes an inflatable balloon.