Abstract: Novel dry powder compositions comprising and methods relating thereto are provided. The dry powder compositions comprise PDE5 inhibitors, such as vardenafil, or pharmaceutically acceptable salts or esters thereof. The dry powder compositions may optionally include an carrier/excipient. The concentration of active agent may be at least about 2% by weight. Methods of aerosolizing the dry powder compositions and using them to treat various diseases are also disclosed.

Abstract: Novel dry powder compositions comprising and methods relating thereto are provided. The dry powder compositions comprise PDE5 inhibitors, such as vardenafil, or pharmaceutically acceptable salts or esters thereof. The dry powder compositions may optionally include an carrier/excipient. The concentration of active agent may be at least about 2% by weight. Methods of aerosolizing the dry powder compositions and using them to treat various diseases are also disclosed.

Abstract: A method, system, and computer-readable storage media for granting a device access to a managed group are disclosed. Identification information may be exchanged between a management device in the managed group and a managed device through a secure first channel. If the identification information is verified by the management device, the managed device may be granted access to the managed group through the secure first channel. If access is granted, the managed device may access the managed group through a secure communication session on a network. If the identification information is not verified, the management device may send a cryptographic key to the managed device through the secure first channel. The cryptographic key may be used to create an encrypted communication session between the managed device and management device over the network.

Abstract: A method, system, and computer-readable storage media for granting a device access to a managed group are disclosed. Identification information may be exchanged between a management device in the managed group and a managed device through a secure first channel. If the identification information is verified by the management device, the managed device may be granted access to the managed group through the secure first channel. If access is granted, the managed device may access the managed group through a secure communication session on a network. If the identification information is not verified, the management device may send a cryptographic key to the managed device through the secure first channel. The cryptographic key may be used to create an encrypted communication session between the managed device and management device over the network.

Abstract: Novel imidazolium compounds of the formula wherein A represents the atomic group necessary to form a heteroaromatic ring, which may be optionally substituted by one or more R substituents selected from the group consisting of aryl, heteroaryl, lower alkyl, hydroxy, halide, or carboxy substitutents; B is an optional substituent which represents the atomic group necessary to form a heteroaromatic ring or a double or triple carbon-nitrogen bond, which may optionally be substituted by one or more R′ substituents selected from the group consisting of aryl, heteroaryl, lower alkyl, hydroxy, halide, or carboxy substitutents; C is an optional substituent which represents the atomic group necessary to form an aromatic or heteroaromatic ring, which may optionally be substituted by one or more R″″ substituents selected from the group consisting of aryl, heteroaryl, lower alkyl, hydroxy, halide, or carboxy substituents; R″ and R′″ are each independently a lower alk

Abstract: Methods of preparation of dyed textiles, fluorescent polymer matrices, fluorescent clonal markers, non-lineal optical polymers and diagnostic imaging agents are described using compounds with the general formula ##STR1## wherein A represents the atomic group necessary to form a heteroaromatic ring, wherein R may be a variety of;wherein P or Q are optional substituents, each independently a substituent selected from the group consisting of aryl, heteroaryl, lower alkyl, hydroxy, halo, lower alkylamino, amino, nitro, or carboxy, or P and Q together represent the atomic group necessary to form a heteroaromatic ring, wherein R' may be a variety of substituents;C is an optional substituent which represents the atomic group necessary to form an aromatic or heteroaromatic ring, wherein R"" may be a variety of substituents;R" is hydrogen, a lower alkyl or aryl group, or together with R'" and the nitrogen atom to which it is attached, form a heterocyclic ring having from 5 to 7 members, which may optionally contain a

Abstract: The present invention relates to novel imidazolium compounds and improved processes for the preparation of imidazolium cations with one or more imidazolium moieties optionally substituted with the same or different substituents, which are prepared from a reactant with at least one N--C--C--N group, by reacting with with an N-substituted or N,N-disubstituted thioformamide, formamide acetal or thioformamide acetal, in the presence of a halogenating agent. Examples of suitable halogenating agents include but are not limited to thionyl chloride, phosgene, and phosgene derivatives. Reactants containing more than one additional N--C--C--N group may also be used to prepare compounds with two or more imidazolium groups, by the procedures of the present invention. Certain compounds of the invention prepared from reactants with multiple N--C--C--N groups may have both unreacted N--C--C--N moieties and substituted imidazolium groups.

Abstract: Novel imidazolium compounds of the formula ##STR1## wherein A represents the atomic group necessary to form a heteroaromatic ring, which may be optionally substituted by one or more R substituents selected from the group consisting of aryl, heteroaryl, lower alkyl, hydroxy, halide, or carboxy substitutents; B is an optional substituent which represents the atomic group necessary to form a heteroaromatic ring or a double or triple carbon-nitrogen bond, which may optionally be substituted by one or more R' substituents selected from the group consisting of aryl, heteroaryl, lower alkyl, hydroxy, halide, or carboxy substitutents; C is an optional substituent which represents the atomic group necessary to form an aromatic or heteroaromatic ring, which may optionally be substituted by one or more R"" substituents selected from the group consisting of aryl, heteroaryl, lower alkyl, hydroxy, halide, or carboxy substituents; R" and R'" are each independently a lower alkyl or aryl group, or together with the nitrogen

Abstract: An aliasing method and apparatus carried out on a digital computer are provided for generating an object code from a source program. An aliasing data structure is defined and includes an initial empty check-list for each variable in the source program. A pseudo variable is constructed to represent each predefined large alias class. The pseudo variable is attached to the check-list of each variable included in the predefined alias class. Inverse alias checking upon use of a variable is provided using the check-lists for the variable.

Abstract: Three separate methods are used to provide the user with sounds that help the user understand where a particular current position is relative to a "location of interest" (LOI) within the viewable object. First, the user is able to use sound marks to mark specific LOIs within viewable objects so that the user may return to those LOIs at a later time. Second, the user is provided with view regions which aurally indicate the LOS of frequeuntly used portions of the viewable object. Lastly, the user is given an aural indication of the current position of the position identifier relative to the viewable object as a whole. This is called relational positioning. Each type of aural LOI indication can be presented to the user regardless of how the user is moving through the viewable object.