Patents by Inventor Robert J. Hondal

Robert J. Hondal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SELENOCYSTINE DERIVATIVES, ALPHA-METHYLSELENOCYSTEINE, ALPHA-METHYLSELENOCYSTEINE DERIVATIVES, AND METHODS OF MAKING AND USING SAME
    Publication number: 20160221941
    Abstract: Provided are selenocysteine derivatives (e.g., deuterium and tritium analogs), ?-methylselenocysteine, and ?-methylselenocysteine derivatives. These compounds can be incorporated in more complex chemical structures (e.g., polymers, proteins, peptides, and enzymes). Also provided are methods of making and using these compounds. The compounds can be used, for example, as drugs, chemical reagents, and redox switchable surfactants.
    Type: Application
    Filed: February 2, 2016
    Publication date: August 4, 2016
    Inventors: Robert J. Hondal, Erik Ruggles
  • DIRECT ASSAY OF THIOREDOXIN REDUCTASE ACTIVITY
    Publication number: 20150050682
    Abstract: Provided is a direct method for detecting thioredoxin reductase (TR) activity in test samples. The method can provide a continuous and real-time measurement of TR activity. The method comprises contacting the test sample with NADPH and a diselenide substrate of TR, and then measuring conversion of NADPH to NADP. Also provided are kits for use in the method of direct detection of TR activity.
    Type: Application
    Filed: August 15, 2014
    Publication date: February 19, 2015
    Inventors: Robert J. Hondal, Nicholas H. Heintz, Brian Cunniff, Nicholas Fredette, Gregg W. Snider