Patents by Inventor Robert J. Losada
Robert J. Losada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11318459Abstract: A method for detecting the presence of a microorganism in a fluid sample is disclosed. The method includes providing a fluid specimen within a specimen collection container having a sidewall defining an interior therein. The interior includes a mechanical separator adapted for separating the fluid sample into first and second phases within the specimen collection container and a sensing element capable of detecting the presence of a microorganism disposed therein. The method includes subjecting the specimen collection container to applied rotational force to isolate a concentrated microorganism region. The method also includes detecting by a sensing element the presence or absence of a microorganism within the concentrated microorganism region.Type: GrantFiled: September 4, 2013Date of Patent: May 3, 2022Assignee: Becton, Dickinson and CompanyInventors: Song Shi, Mei Yang, Klaus W. Berndt, Robert J. Losada, Jamieson W. Crawford, Ravi Attri, Christopher A. Battles, Benjamin R. Bartfeld, Gregory R. Hires
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Publication number: 20170266661Abstract: A separation assembly for separation of a fluid into first and second parts is disclosed. A container has a first end, a second end, and a sidewall extending therebetween defining an interior, the container defining a longitudinal axis between the first end and the second end. A separator body is disposed within the interior having a through-hole defined therethrough. The separator body includes a first part, and a second part interfaced with the first part, wherein the separator body is transitionable from a first position wherein the through-hole is provided in fluid-receiving alignment with the first end of the container, to a second position wherein the through-hole is provided substantially perpendicular to the longitudinal axis of the container. In the first position, a through-axis of the through-hole of the separator body is in a plane that is not parallel with a plane containing the longitudinal axis of the container.Type: ApplicationFiled: June 5, 2017Publication date: September 21, 2017Inventors: Robert J. Losada, Arun U. Nair
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Patent number: 9724690Abstract: Disclosed is a fluid collection device wherein multiple, individual samples of fluid can be collected simultaneously. The device includes a chamber and an adapter which substantially and simultaneously distributes the blood to individual chambers with chamber specific additives. Also included is a system for using the blood collection device, preferably within a diagnostic testing laboratory.Type: GrantFiled: February 8, 2007Date of Patent: August 8, 2017Assignee: Becton, Dickinson and CompanyInventors: Gary D. Fletcher, Sol F. Green, Myriam Lopez, Robert J. Losada, Dimitrios Manoussakis, C. Mark Newby, Girish Parmar, Paul R. Soskey, Timothy A. Stevens, Yuguang Wu
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Patent number: 9694359Abstract: A separation assembly for separation of a fluid into first and second parts is disclosed. A container has a first end, a second end, and a sidewall extending therebetween defining an interior, the container defining a longitudinal axis between the first end and the second end. A separator body is disposed within the interior having a through-hole defined therethrough. The separator body includes a first part, and a second part interfaced with the first part, wherein the separator body is transitionable from a first position wherein the through-hole is provided in fluid-receiving alignment with the first end of the container, to a second position wherein the through-hole is provided substantially perpendicular to the longitudinal axis of the container. In the first position, a through-axis of the through-hole of the separator body is in a plane that is not parallel with a plane containing the longitudinal axis of the container.Type: GrantFiled: February 24, 2015Date of Patent: July 4, 2017Assignee: Becton, Dickinson and CompanyInventors: Robert J. Losada, Arun U. Nair
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Patent number: 9682373Abstract: A separator for use in a container for a biological fluid is disclosed. The separator includes a separator body having a first region at least partially made of a first material having a first density, and a second region at least partially made of a second material having a second density different from the first density. The separator has an overall density intermediate the densities of a first phase and a second phase of the biological fluid. At least a portion of the separator is deformable between a first condition in which the biological fluid can pass between an inner surface of the container and the separator, and a second condition in which at least a portion of the separator prevents the biological fluid from passing between the inner surface of the container and the separator.Type: GrantFiled: April 15, 2013Date of Patent: June 20, 2017Assignee: Becton, Dickinson and CompanyInventors: Robert J. Losada, Gregory L. Lusardi, Fu-Chung Lin
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Publication number: 20160136639Abstract: A mechanical separator and separation assembly for separating a fluid sample into first and second parts within a collection container is disclosed. The mechanical separator has a body having a through-hole for allowing fluid to pass therethrough and includes a first portion, having a first density, and a second portion, having a second density different from the first density. The body defines a longitudinal axis extending perpendicular to the through-hole, and exhibits a first compression value when a force is applied to the body along this axis. The body also defines an axis extending perpendicular to the longitudinal axis and along the through-hole and exhibits a second compression value when a force is applied along this axis. The first compression value is different than the second compression value and may be less than the second compression value.Type: ApplicationFiled: February 24, 2015Publication date: May 19, 2016Inventor: Robert J. Losada
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Publication number: 20160136640Abstract: A separation assembly for separation of a fluid into first and second parts is disclosed. A container has a first end, a second end, and a sidewall extending therebetween defining an interior, the container defining a longitudinal axis between the first end and the second end. A separator body is disposed within the interior having a through-hole defined therethrough. The separator body includes a first part, and a second part interfaced with the first part, wherein the separator body is transitionable from a first position wherein the through-hole is provided in fluid-receiving alignment with the first end of the container, to a second position wherein the through-hole is provided substantially perpendicular to the longitudinal axis of the container. In the first position, a through-axis of the through-hole of the separator body is in a plane that is not parallel with a plane containing the longitudinal axis of the container.Type: ApplicationFiled: February 24, 2015Publication date: May 19, 2016Inventors: Robert J. Losada, Arun U. Nair
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Publication number: 20150231626Abstract: A method for detecting the presence of a microorganism in a fluid sample is disclosed. The method includes providing a fluid specimen within a specimen collection container having a sidewall defining an interior therein. The interior includes a mechanical separator adapted for separating the fluid sample into first and second phases within the specimen collection container and a sensing element capable of detecting the presence of a microorganism disposed therein. The method includes subjecting the specimen collection container to applied rotational force to isolate a concentrated microorganism region. The method also includes detecting by a sensing element the presence or absence of a microorganism within the concentrated microorganism region.Type: ApplicationFiled: September 4, 2013Publication date: August 20, 2015Inventors: Song Shi, Mei Yang, Klaus W. Berndt, Robert J. Losada, Jamieson W. Crawford, Ravi Attri, Christopher A. Battles, Benjamin R. Bartfeld, Gregory R. Hires
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Patent number: 9095849Abstract: A separator for use in a container for a biological fluid is disclosed. The separator includes a separator body having a first region at least partially made of a first material having a first density, and a second region at least partially made of a second material having a second density different from the first density. The separator has an overall density intermediate the densities of a first phase and a second phase of the biological fluid. At least a portion of the separator is deformable between a first condition in which the biological fluid can pass between an inner surface of the container and the separator, and a second condition in which at least a portion of the separator prevents the biological fluid from passing between the inner surface of the container and the separator.Type: GrantFiled: April 11, 2013Date of Patent: August 4, 2015Assignee: Becton, Dickinson and CompanyInventors: Robert J. Losada, Gregory L. Lusardi, Fu-Chung Lin
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Publication number: 20130241099Abstract: A separator for use in a container for a biological fluid is disclosed. The separator includes a separator body having a first region at least partially made of a first material having a first density, and a second region at least partially made of a second material having a second density different from the first density. The separator has an overall density intermediate the densities of a first phase and a second phase of the biological fluid. At least a portion of the separator is deformable between a first condition in which the biological fluid can pass between an inner surface of the container and the separator, and a second condition in which at least a portion of the separator prevents the biological fluid from passing between the inner surface of the container and the separator.Type: ApplicationFiled: April 15, 2013Publication date: September 19, 2013Applicant: Becton, Dickinson and CompanyInventors: Robert J. Losada, Gregory L. Lusardi, Fu-Chung Lin
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Publication number: 20130230438Abstract: A separator for use in a container for a biological fluid is disclosed. The separator includes a separator body having a first region at least partially made of a first material having a first density, and a second region at least partially made of a second material having a second density different from the first density. The separator has an overall density intermediate the densities of a first phase and a second phase of the biological fluid. At least a portion of the separator is deformable between a first condition in which the biological fluid can pass between an inner surface of the container and the separator, and a second condition in which at least a portion of the separator prevents the biological fluid from passing between the inner surface of the container and the separator.Type: ApplicationFiled: April 11, 2013Publication date: September 5, 2013Applicant: Becton, Dickinson and CompanyInventors: Robert J. Losada, Gregory L. Lusardi, Fu-Chung Lin
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Patent number: 8524171Abstract: A device for separating heavier and lighter fractions of a fluid sample is provided, the device including a container and a unitary separator located therein, the separator having an overall density between the heavier and light fractions. The separator is capable of moving between the fractions upon centrifugation, and sealing the fractions from one another when centrifugation ends.Type: GrantFiled: April 13, 2011Date of Patent: September 3, 2013Assignee: Becton, Dickinson and CompanyInventors: Robert J. Losada, Gregory L. Lusardi, Fu-Chung Lin
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Publication number: 20110187021Abstract: A device for separating heavier and lighter fractions of a fluid sample is provided, the device including a container and a unitary separator located therein, the separator having an overall density between the heavier and light fractions. The separator is capable of moving between the fractions upon centrifugation, and sealing the fractions from one another when centrifugation ends.Type: ApplicationFiled: April 13, 2011Publication date: August 4, 2011Applicant: BECTON, DICKINSON AND COMPANYInventors: Robert J. Losada, Fu-Chung Lin, Gregory L. Lusardi
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Patent number: 7947236Abstract: A device for separating heavier and lighter fractions of a fluid sample is provided, the device including a container and a unitary separator located therein, the separator having an overall density between the heavier and light fractions. The separator is capable of moving between the fractions upon centrifugation, and sealing the fractions from one another when centrifugation ends.Type: GrantFiled: February 24, 2004Date of Patent: May 24, 2011Assignee: Becton, Dickinson and CompanyInventors: Robert J. Losada, Fu-Chung Lin, Gregory L. Lusardi
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Publication number: 20090130646Abstract: Disclosed is a fluid collection device wherein multiple, individual samples of fluid can be collected simultaneously. The device includes a chamber and an adapter which substantially and simultaneously distributes the blood to individual chambers with chamber specific additives. Also included is a system for using the blood collection device, preferably within a diagnostic testing laboratory.Type: ApplicationFiled: February 8, 2007Publication date: May 21, 2009Applicant: BECTON, DICKINSON AND COMPANYInventors: Gary D. Fletcher, Sol F. Green, Myriam Lopez, Robert J. Losada, Dimitrios Manoussakis, C. Mark Newby, Girish Parmar, Paul R. Soskey, Timothy A. Stevens, Yuguang Wu
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Patent number: 7500569Abstract: A device for separating plasma from whole blood is provided having an evacuated primary collection chamber capable of fluid communication through a porous filter to an evacuated secondary collection chamber. An agglutinating agent is provided within the primary collection chamber so as to aggregate blood cells within a whole blood sample. The porous filter has a pore size which is small enough to capture the aggregated blood cells therein, yet large enough to permit plasma to transfer therethrough under pressures associated with conventional evacuated blood collection tubes. The primary and secondary collection chambers may be provided in separate containers or tubes, with transfer occurring therebetween through a transfer device including the porous filter therein.Type: GrantFiled: December 17, 2004Date of Patent: March 10, 2009Assignee: Becton, Dickinson and CompanyInventors: Dimitrios Manoussakis, Robert J. Losada
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Publication number: 20040166029Abstract: A device for separating heavier and lighter fractions of a fluid sample is provided, the device including a container and a unitary separator located therein, the separator having an overall density between the heavier and light fractions. The separator is capable of moving between the fractions upon centrifugation, and sealing the fractions from one another when centrifugation ends.Type: ApplicationFiled: February 24, 2004Publication date: August 26, 2004Inventors: Robert J. Losada, Fu-Chung Lin, Gregory L. Lusardi
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Patent number: 6479298Abstract: A device and method for separating heavier and lighter fractions of a fluid sample. The device includes a plurality of constituents comprising a container and a composite element in the container. The composite element is a separator comprising at least two components and more particularly, a bellows with a seal body, a low-density float and a high-density ballast. A fluid sample is delivered to the container and the device is subjected to centrifugation whereby the centrifugal load causes the seal body of the separator to deform so that the separator migrates through the fluid sample and then stabilizes between the heavier and lighter fractions of the fluid sample. The seal body of the separator will resiliently return to its initial configuration upon termination of the centrifugal load such that the seal body sealingly engages the container and the composite element separates the heavier and lighter fractions of the fluid sample.Type: GrantFiled: December 3, 1999Date of Patent: November 12, 2002Assignee: Becton, Dickinson and CompanyInventors: Henry F. Miller, Fu-Chung Lin, Robert J. Losada, Jeffrey P. Radziunas, Jeffrey Karg
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Publication number: 20020132367Abstract: A device and method for separating heavier and lighter fractions of a fluid sample. The device includes a plurality of constituents comprising a container and a composite element in the container. The composite element is a separator comprising at least two components and more particularly, a bellows with a seal body, a low-density float and a high-density ballast. A fluid sample is delivered to the container and the device is subjected to centrifugation whereby the centrifugal load causes the seal body of the separator to deform so that the separator migrates through the fluid sample and then stabilizes between the heavier and lighter fractions of the fluid sample. The seal body of the separator will resiliently return to its initial configuration upon termination of the centrifugal load such that the seal body sealingly engages the container and the composite element separates the heavier and lighter fractions of the fluid sample.Type: ApplicationFiled: March 11, 2002Publication date: September 19, 2002Inventors: Henry F. Miller, Fu-Chung Lin, Robert J. Losada, Jeffrey P. Radziunas, Jeffrey Karg
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Patent number: 4967763Abstract: A blood collection assembly includes a plasma-treated blood collection container and a blood collector which optionally may also be plasma-treated. The collector has a body portion providing a blood passageway between the container and a scoop shaped portion which contacts a puncture wound. A vent in the collector allows air displacement from the container when blood enters. The inside wall of the container has longitudinal ribs molded thereon and an altered surface chemistry characterized by an enhanced oxygen content. The invention includes a method to increase blood flow across the interior surface of a plastic blood collection container comprising plasma treatment of the surface.Type: GrantFiled: March 13, 1989Date of Patent: November 6, 1990Assignee: Becton, Dickinson and CompanyInventors: Edward Nugent, Robert J. Losada, Hugh T. Conway, David B. Montgomery, Joel L. Williams