Abstract: A liquid concentrate generation system may comprise a manifold having an inlet receptacle including a first piercing member, an outlet receptacle including a second piercing member, and a flow channel connecting the inlet receptacle and outlet receptacle. The system may further comprise a cartridge having an inlet port and an outlet port sealed by a respective first and second cover. The inlet and outlet port may be respectively configured to displace within the inlet receptacle and outlet receptacle from an unspiked position to a spiked position. First and second piercing members may be in communication with the flow channel and spaced apart respectively from the first and second cover in the unspiked position. The first and second piercing members may be isolated from the flow channel and may respectively puncture the first and second cover in the spiked position.

Abstract: Emulsion-based and micromolded (“MM”) or three dimensional printed (“3DP”) polymeric formulations for single injection of antigen, preferably releasing at two or more time periods, have been developed. Formulations are preferably formed of biocompatible, biodegradable polymers. Discrete regions encapsulating antigen, alone or in combination with other antigens, adjuvants, stabilizers, and release modifiers, are present in the formulations. Antigen is preferably present in excipient at the time of administration, or on the surface of the formulation, for immediate release, and incorporated within the formulation for release at ten to 45 days after initial release of antigen, optionally at ten to 90 day intervals for release of antigen in one or more additional time periods. Antigen may be stabilized through the use of stabilizing agents such as trehalose glass. In a preferred embodiment for immunization against polio, antigen is released at the time of administration, and two, four and six months thereafter.

Abstract: An electrical power system for a delivery vehicle is provided. The power system is used in connection with a delivery vehicle having an engine, and also having a liftgate powered by an electric motor. The electrical power system includes a first battery, a second battery, and an alternator. The electrical power system also includes a super capacitor. The super capacitor has a first capacitor bank and a second capacitor bank, wherein each of the first capacitor bank and the second capacitor bank comprises ultra-capacitor cells placed in series. The first capacitor bank and the second capacitor bank reside in parallel. In addition, the first battery and the second battery reside in parallel with the second capacitor bank. Together, the first battery, the second battery and the second capacitor bank supply power to the liftgate motor.