Abstract: Embodiments include an electronic package with an embedded multi-interconnect bridge (EMIB) and methods of making such packages. Embodiments include a first layer, that is an organic material and a second layer disposed over the first layer. In an embodiment, a cavity is formed through the second layer to expose a first surface of the first layer. A bridge substrate is in the cavity and is supported by the first surface of the first layer. Embodiments include a first die over the second layer that is electrically coupled to a first contact on the bridge substrate, and a second die over the second layer that is electrically coupled to a second contact on the bridge substrate. In an embodiment the first die is electrically coupled to the second die by the bridge substrate.

Abstract: A pop up stopper comprising multiple aperture and at least one non-aperture lever rod engagement locations to allow use of the stopper as a replacement with different pre-existing actuating and drain systems when the existing stopper is broken, worn or needs to be replaced for aesthetic reasons. An existing lever rod is selectively positionable to engage with one of the lever rod engagement locations that are disposed at varying heights on the stopper. Most preferably, there are six lever rod engagement locations, four aperture locations and two non-aperture locations. A seal disposed below a cap and around a body of the stopper comprises an enlarged annular ring near its outer edge to provide increased surface area for sealing a drain opening. The body of the stopper has a maximum width measured in cross section of 1.04 inches or less.

Abstract: A button for a drug delivery device with a reduced operating loudness includes a plate-like button body forming a touch surface, wherein the plate-like button body is coupled by an axial supporting member to a noise-generating interface of the drug delivery device and movable into a longitudinal direction of the drug delivery device, wherein the plate-like button body includes a material composite with at least one first component consisting of a first material and at least one second component consisting of a second material different from the first material, wherein the at least one first component and the at least one second component are coupled via at least one coupling plane that is at least sectionwise slanted or perpendicular to the longitudinal direction. Further, the disclosure describes a button assembly for a drug delivery device which is shock resistant.

Abstract: The invention relates to a rail vehicle (1) comprising a first passenger car and a powerpack (2) having a longitudinal axis, the powerpack (2) and the passenger car being coupled together. The powerpack (2) comprises at least one fuel cell (20) and at least one fuel tank (21) having a fuel tank valve (33). The powerpack (2) is mounted on at least one bogie. The rail vehicle (1) comprises at least one driven bogie which can be supplied with electrical energy from the fuel cell (20).

Abstract: An electrical assembly including a grounding mechanism and an electrical device, the grounding mechanism including a support longitudinal member and a switch contact member, the switch contact member arranged in or on the support longitudinal member, the switch contact member configured to be connected in use to ground, the electrical device including an electrical terminal, wherein the support longitudinal member is configured to be slidable between: a first position in which the switch contact member is separated from the electrical terminal so that the switch contact member is electrically disconnected from the electrical device and a second position in which the switch contact member is in contact with the electrical terminal so that the switch contact member is electrically connected to the electrical device.

Abstract: Disclosed are various examples for enrollment of gateway enrollment for Internet-of-Things (IoT) device management. In some examples, a client device receives a gateway management installation package from a management service. The client device installs a gateway management application to the gateway device using the installation package. Enrollment credentials are entered through a user interface generated using the gateway management application and shown on the client device. The client device instructs the gateway management application enroll the gateway device with the management service. Usage of the enrollment credentials prevents a user from being exposed to gateway credentials that authenticate communications between the gateway device and the management service.

Abstract: Embodiments of the instant disclosure relate to novel methods and compositions for treating tumors resistant to platinum-based chemotherapy. In certain embodiments, methods of treating tumors herein can include administering an effective amount of at least one M1 aminopeptidase inhibitor in combination with at least one platinum-based chemotherapeutic agent separately or in a combination therapy. In some embodiments, methods of treating tumors disclosed herein can include screening and/or selecting a subject suitable for treatment based on NPEPPS gene or protein expression in the tumor to be treated. In other embodiments, methods of treating tumors can include administering a composition including a combination of at least one M1 aminopeptidase inhibitor and at least one platinum-based chemotherapeutic agent. In certain embodiments, compositions disclosed herein can include at least tosedostat and carboplatin.

Abstract: Test cartridges for performing multi-target assay panels, in particular multiplex vaginal panels (MVP) and methods of use and manufacture. Such cartridges can include a cartridge body having multiple chambers and rotatable valve assembly to facilitate controlled fluid flow, and various reagents and buffers to chemically lyse nucleic acids from multiple targets in MVP. Specialized valve assemblies have been utilized to resist alkaline lysing buffers required to chemically lyse multiple targets, including various protozoa, yeasts and bacteria, including Atopobium spp. (Atopobium vaginae, Atopobium novel species CCUG 55226); Bacterial Vaginosis-Associated Bacterium 2 (BVAB2); and Megasphaera-1. Methods include detecting levels of each respective target in a single sample from a single multi-target assay cartridge and identifying the subject as having bacterial vaginosis, vulvovaginal candidiasis (or the presence of Candida spp.

Abstract: An in-wheel electrical generator for a vehicle is disclosed. The in-wheel generator comprises: a stator configured to be coupled to a non-rotating spindle of a vehicle; and a rotor configured to be indirectly coupled to a rotating hub of a vehicle. The in-wheel electrical generator is configured to be arranged outwardly of the rotating hub. A vehicle comprising such an in-wheel generator is also disclosed, along with an ancillary unit system for a trailer which uses such an in-wheel generator to power the ancillary unit.

Abstract: Embodiments of the disclosure provide a structure and canopy for mounting of a photovoltaic panel. A structure of the disclosure may provide a rail mounting clip including a first segment shaped for mounting on a purlin surface, a second segment at a lateral end of the first segment and extending perpendicularly outwardly therefrom. A rail assembly is coupled to the rail mounting clip and has a slot substantially aligned with a centerline axis of the rail assembly. The slot receives the second segment of the rail mounting clip, and the rail assembly is shaped for mounting a photovoltaic panel thereon.

Abstract: A system for displaying medical imaging data comprising one or more data inputs, one or more processors, and one or more displays, wherein the one or more data inputs are configured for receiving first image data generated by a first medical imaging device, wherein the first image data comprises a field of view (FOV) portion and a non-FOV portion, and the one or more processors are configured for identifying the non-FOV portion of the first image data and generating cropped first image data by removing at least a portion of the non-FOV portion of the first image data, and transmitting the cropped first image data for display in a first portion of the display and additional information for display in a second portion of the display.

Abstract: Various aspects related to methods, systems, and computer readable media for restricting processes being executed on a user device. A method can include, for example, receiving an indication of a security threat to a user device associated with a user, identifying a first plurality of processes being executed on the user device, identifying a second plurality of trusted processes from the first plurality of processes, receiving, from a remote device in operative communication with the user device, a command to terminate or suspend one or more processes from the first plurality of processes that are not in the second plurality of trusted processes, and, after the terminating or suspending, remediating the security threat on the user device.

Abstract: Various aspects related to methods, systems, and computer readable media for centralized management of policies for network-accessible devices. An example method for deploying network policies to one or more computing devices or services can include receiving a request to analyze a network-accessible item for malicious activity, determining that the analyzed network-accessible item is associated with the malicious activity, presenting, at a client device, a listing of selectable devices and services responsive to the determination, wherein the listing is populated based on identifying data of the user, receiving at least one selection from the listing of selectable devices and services, creating at least one network access policy based on the at least one selection, and, deploying the at least one network access policy to a device or service associated with the at least one selection.

Abstract: Various aspects related to methods, systems, and computer readable media for restricting processes being executed on a user device. A method can include, for example, receiving an indication of a security threat from a security threat indication service being executed by a user device, wherein the indication of the security threat has been initiated by the user, presenting, at the user device, one or more questions based on the indication of the security threat, receiving one or more responses to the one or more questions from the user, and, automatically remediating the security threat on the user device based upon the received one or more responses.

Abstract: A method includes storing an employment status module associated with an entity and associating a plurality of employment statuses with respective security settings for a plurality of users associated with the entity, receiving information indicating a change in an employment status of a user of the plurality of users, determining a change to security settings for the user based on the change in the employment status of the user, applying the change to the security settings for the user in a security management system of the threat management facility, and restricting use of at least one data processing electronic device activity on an electronic device of the user based on the change to the security settings for the user.

Abstract: Disclosed herein is an implantable medical device including a housing, a header, a connector port, and a collet assembly. The header can be arranged with the housing. The connector port can be arranged within the header and configured to couple an implantable lead to the header. The collet assembly can be arranged within the connector port and configured to frictionally engage a portion of the implantable lead and to secure the implantable lead with the header in response to insertion of the portion of the implantable lead into the connector port.

Abstract: A chainsaw hanger has a flat face with a J-shaped support arm extending perpendicular to and vertically downward from the face, curving to form a horizontal portion parallel to and spaced laterally from the face, and a vertical portion extending upward towards and spaced laterally from a bottom surface of the face. The chainsaw hanger supports a chain saw in a vertical position abutting a wall. The support arm of a lockable chainsaw hanger has a pair of apertures spaced to accommodate a U-shaped rod having legs extending downward. One leg is slidably and rotatably secured within the support arm.

Abstract: Disclosed herein is an implantable medical device including a housing, a header, a connector port, and a collet assembly. The header can be arranged with the housing. The connector port can be arranged within the header and configured to couple an implantable lead to the header. The collet assembly can be arranged within the connector port and configured to frictionally engage a portion of the implantable lead and to secure the implantable lead with the header in response to insertion of the portion of the implantable lead into the connector port.