Abstract: A medical instrument is disclosed that includes an elongated probe section having a length (L) between a proximal and a distal probe section end. The probe section includes a plurality of carbon fibers that is arrayed along the axis and embedded in a medical grade, biocompatible epoxy resin. The probe section is constructed to be rigid by controlling the density of carbon fibers such that the maximum predetermined off-axis deflection (dmax) is less than about 30% of the probe section length (dmax<0.3 L). A handle is affixed, and positioned to be coaxial with, the proximal end of the probe section. For the instrument, the probe section is constructed of materials that are impervious to an imaging modality (e.g. magnetic fields). For example, with this construction, the probe section can be immersed in a homogenous magnetic field that is established by an MRI system without distorting the resulting MRI image.

Abstract: Embodiments disclosed herein relate to syringe systems for delivering and removing materials, instrument kits that include the syringe systems provided herein, and methods of using the syringe systems and kits provided herein.

Abstract: A cell cluster from which unwanted components are removed by efficiently washing the cell cluster is collected. Provided is a cell washing method including a centrifuging step (S1) of collecting a cell suspension in a centrifuge container having a washing fluid discharge port opposing a bottom part and centrifugally separating cells at the bottom part by rotating in such a manner that the bottom part faces outward in the radial direction; a supernatant ejecting step (S2) of ejecting a supernatant centrifugally separated in the centrifuging step (S1); and a washing step (S3) of discharging the washing fluid from the discharge port while rotating the centrifuge container while ejecting the supernatant in the supernatant ejecting step (S2).

Abstract: A cell suspension that contains a cell group from which unwanted components have been removed by efficiently washing the cell group is recovered. A centrifuge container (1) includes a cylindrical container main body (2) that accommodates a cell suspension and is rotated with a bottom portion (2a) being directed radially outward; a supernatant suction tube (4) that has a first opening (4a) at a position in the depth direction of the container main body (2) and that suctions a supernatant obtained by centrifuging the cell suspension, in the radial direction of the container main body (2); and a washing-fluid discharge tube (3) that have a second opening (3a) at a position in the depth direction of the container main body (2) and that discharge a washing fluid in the axial direction toward the bottom portion (2a) of the container main body (2).

Abstract: The count of cells that are to be concentrated in a centrifugal container and transplanted can be measured without damaging these cells. Disclosed is a cell processing device comprising: a centrifugal separator which concentrates cells by rotating a centrifugal container that contains a cell suspension yielded by digestion of a biological tissue; a property detection unit which detects a property of the cell suspension contained in the centrifugal container of the centrifugal separator; and a cell count enumeration unit which calculates the cell count on the basis of the property of the cell suspension detected by the property detection unit.

Abstract: Embodiments disclosed herein relate to syringe systems for delivering and removing materials, instrument kits that include the syringe systems provided herein, and methods of using the syringe systems and kits provided herein.

Abstract: Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.