Abstract: A switch assembly that is utilized as a tail cap of a lighting device. The switch assembly comprises a depressible switch that allows the user to activate the lighting device. In an illustrative, non-limiting embodiment, the switch assembly has four channels, providing for at least three different light functions and a locking channel. In these non-limiting embodiments, the different channels are defined by the axial position of the rotatable portion relative to the lighting device body.

Abstract: Methods, systems and computer readable media for visualizing a collection of graphs, wherein each of the graphs may be aligned along one axis of a visualization. All graphs are aligned with respect to the one axis. At least one metadata value per graph is aligned in a first form of representation with each graph, respectively. Visualization of the graphs are compressed in a direction along a second axis perpendicular to the first axis, and visualizations of the metadata values aligned with the compressed visualizations of the graphs are represented graphically.

Abstract: An adjustable accessory mounting clamp for mounting an accessory to an accessory rail, including a primary locking arm; a secondary locking arm; a threaded adjustment rod that is anchored, at a first end, to the primary locking arm, extends through an aperture in the secondary locking arm, and is threadedly coupled to a cam lever pin of a cam lever, wherein the cam lever includes at least one caming surface, such that when the cam lever is in a closed position, the caming surface contacts an outer surface portion of the secondary locking arm to provide tension to the threaded adjustment rod; such that a distance between the primary locking claw and the secondary locking claw is adjusted to accommodate varying width accessory mounting rails.

Abstract: A holster for a handgun having a holster body defining a cavity for receiving and holding a handgun, a pivot guard pivotably coupled to the body and pivotable between a closed position for securing a handgun within the cavity and an open position for insertion or removal of the handgun, wherein the pivot guard includes a pivot guard locking means for receiving at least a portion of a pivot guard locking portion for securing the pivot guard in the closed position, and wherein the pivot guard includes a locking extension that extends from each side of the pivot guard and the holster body includes a corresponding retaining channels formed within the cavity such that when the pivot guard is in the closed position, each locking extension of the pivot guard extends into a corresponding retaining channel of the holster body.

Abstract: Disclosed is a holster for a weapon such as a handgun which includes a body defining a cavity for receiving and holding the weapon, a hood assembly pivotably connected to the body, the hood assembly pivotable between a closed position for securing the weapon within the body cavity and an open position for removal of the weapon, a locking mechanism securing the hood assembly in the closed position when a weapon is held in the body cavity, a release mechanism associated with the locking mechanism for releasing the hood assembly to the open position for removal of the weapon, and a mechanism for automatically pivoting the hood assembly to the closed position and thereby automatically engaging the locking mechanism upon insertion of the weapon into the body cavity, wherein the locking mechanism is biased to a locked configuration when the weapon is held in the body cavity.

Abstract: Visualization techniques tools and systems for displaying network diagrams to convey both focus and context to a user of the display. Network diagrams may be displayed to emulate a three dimensional presentation. Network diagrams may be presented with items of interest in sharp definition and the remainder of a diagram or diagrams being blurred or having relative degrees of sharpness/blurriness.

Abstract: Methods, systems and computer readable media for calling out genetic aberrations. Log ratio noise associated with log ratio signals read from respective probes on at least one array for signals representative of the same chromosomal locations in a test sample of nucleic acids and a reference sample of nucleic acids applied to the at least one array are estimated. Outliers for log ratio values from the reference sample to outliers for log ratio values from the test sample are compared. A copy number of one or more of the chromosomal locations in the test sample is outputted relative to the reference sample for viewing by a user.

Abstract: Systems and methods for performing programmatic queries about molecular and biomolecule information. The methods comprise creating one or more databases of molecular data formatted or conditioned according to a directory service protocol, forming, by a user, a query based on a molecular identifier or other molecular indicia, submitting the query to a name server, performing a lookup in the databases based on the molecular name or identifier, retrieving a query result or results from the databases, and returning the query results to the user.

Abstract: Methods, systems and computer readable media for sequencing a biopolymer specimen and tracking a source from which the specimen was derived. Methods, systems and computer readable media for multiplex sequencing biopolymer samples. Methods, systems and computer readable media for efficiently sequencing biopolymeric specimens through a high-throughput sequencer. Methods, systems and computer readable media for performing ratio-based analysis with a high throughput sequencer.

Abstract: Embodiments of the present invention include methods and systems for analysis of comparative genomic hybridization (“CGH”) data, including CGH data obtained from microarray experiments. Various embodiments of the present invention include parametric and non-parametric normalization methods for CGH data, methods for identifying sets of one or more contiguous chromosomal DNA subsequences that are amplified or deleted in cells from particular tissue samples, and methods for determining amplifications and deletions common to a set of analyzed samples. When combined with well-designed microarray-based experimental systems, method embodiments of the present invention provide markedly increased quantitative precision in the identification of chromosomal abnormalities, including amplified and deleted DNA subsequences based on CGH data.

Abstract: Methods, systems and computer readable media for visualizing a collection of graphs, wherein each of the graphs may be aligned along one axis of a visualization. All graphs are aligned with respect to the one axis. At least one metadata value per graph is aligned in a first form of representation with each graph, respectively. Visualization of the graphs are compressed in a direction along a second axis perpendicular to the first axis, and visualizations of the metadata values aligned with the compressed visualizations of the graphs are represented graphically.

Abstract: Disclosed is a holster for a weapon such as a handgun which includes a body defining a cavity for receiving and holding the weapon, a hood assembly pivotably connected to the body, the hood assembly pivotable between a closed position for securing the weapon within the body cavity and an open position for removal of the weapon, a locking means securing the hood assembly in the closed position when a weapon is held in the body cavity, a release means associated with the locking means for releasing the hood assembly to the open position for removal of the weapon, and means for automatically pivoting the hood assembly to the closed position and thereby automatically engaging the locking means upon insertion of the weapon into the body cavity, wherein the locking means is biased to a locked configuration when the weapon is held in the body cavity.

Abstract: Systems, methods and computer readable media for performing a domain-specific metasearch, and obtaining search results therefrom. A metasearch engine capable of accessing generic, web-based search engines and domain-relevant search engines is provided to receive one or more queries inputted by a user, and to search for documents on at least one the generic, web-based search engines and domain-relevant search engines which are relevant to the queries. Raw data search results are fetched in the form of text documents. Relevant data including semantic information are extracted from the raw data search results, and converted to a local format. The relevant data having been converted to the local format may be visualized as a network visualization. Additionally or alternatively, the raw data search results may be ranked and/or filtered based on the linking of the relevant data.

Abstract: Methods for generating mixtures of nucleic acids, e.g., oligonucleotide primers, are provided. In the subject methods, an array is employed as template to generate mixtures of nucleic acids via a template driven primer extension reaction. In preferred embodiments, each probe on the array employed in the subject methods comprises a constant domain and a variable domain, where the constant domain is further characterized by having at least a recognition domain. Also provided are the arrays employed in the subject methods and kits for practicing the subject methods. The subject methods find use in a variety of applications, including the generation of target nucleic acids from an mRNA sample for use in hybridization assays, e.g., differential gene expression analyses.

Abstract: Methods, systems and computer readable media for correlating data from data sets to higher level categories of characterization of the data. Data from a first set of data is analyzed to determine where members of the first set map to an ontology. Data from a second set of data is analyzed to determine where members of the second set map to the ontology. From such analysis a subset of the first set of data is identified and a subset of the second set of data is identified. The subset of the first set of data is statistically analyzed with regard to its mapping to the ontology, and a first set of ontology terms are identified that are statistically differentiated by members of the subset of the first set of data. The subset of the second set of data is statistically analyzed with regard to its mapping to the ontology, and a second set of ontology terms is identified that are statistically differentiated by members of the subset of the second set of data.

Abstract: A system and methods for selecting single-features from a microarray scan image of genomic data and rearranging the selected single-features of the microarray into a virtual array having a format or arrangement that is more relevant or informative to the analyst or user than that of the original microarray scan image.

Abstract: Systems, tools, methods and computer readable media for visualizing a collection of graphs to provide context and focus. A compressed visualization is formed by compressing all of the graphs in a direction along a compression axis of the visualization. At least one of the compressed graphs may be zoomed to make a visualization of the at least one graph having a greater scale along the second axis than a scale of the compressed graphs. The zoomed graph or graphs may be displayed along with the compressed graphs, wherein the zoomed graph or graphs are displayed in a same order relative to the compressed graphs and each other as occupied prior to the zooming.

Abstract: Systems, methods and recordable media for facilitating user-guidance of statistical analysis of large datasets based upon word-based textual annotations associated with the large datasets. Particular applications to large biological datasets are described.