Abstract: Provided herein are methods for the treatment of spinal cord injury in a subject by administering vagus nerve stimulation. In particular, the vagus nerve stimulation is administered in combination with conventional rehabilitation training.

Abstract: Systems and methods for stimulating tissue. Exemplary embodiments include systems and methods configured to maintain one electrode at a fixed voltage potential and switching a second electrode between different fixed voltage potentials.

Abstract: Systems and methods for optimizing targeted neuroplasticity training. Exemplary embodiments include a vagus nerve stimulator, a controller, and a monitoring device.

Abstract: A method for treating neural deficits resulting from multiple sclerosis, involving assessing a subject's motor, sensory, cognitive, or emotional deficits caused by multiple sclerosis; selecting a rehabilitative task based said deficits; determining the subject's acceptable performance threshold for the rehabilitative task; and providing a paired training therapy. The paired training therapy comprises having the subject to perform a trial of the rehabilitative task; classifying the subject's performance on the trial as either acceptable or unacceptable, wherein an acceptable performance is performance at or above the subject's acceptable performance threshold, and an unacceptable performance is performance below the subject's acceptable performance threshold; and reinforcing acceptable performance by selectively stimulating the subject's vagus nerve after completion of the acceptable performance.

Abstract: Provided herein are methods for the treatment of spinal cord injury in a subject by administering vagus nerve stimulation. In particular, the vagus nerve stimulation is administered in combination with conventional rehabilitation training.

Abstract: Systems and methods for stimulating tissue. Exemplary embodiments include systems and methods configured to maintain one electrode at a fixed voltage potential and switching a second electrode between different fixed voltage potentials.

Abstract: A method for improving speech recognition, involving assessing a subject's speech recognition ability, selecting a set of speech sounds appropriate for speech recognition training, providing a paired training therapy, and repeating the paired training therapy. The paired training therapy involves selecting a speech sound from the set of speech sounds and introducing said speech sound while concurrently stimulating the subject's vagus nerve.

Abstract: A method for treating neural deficits resulting from multiple sclerosis, involving assessing a subject's motor, sensory, cognitive, or emotional deficits caused by multiple sclerosis; selecting a rehabilitative task based said deficits; determining the subject's acceptable performance threshold for the rehabilitative task; and providing a paired training therapy. The paired training therapy comprises having the subject to perform a trial of the rehabilitative task; classifying the subject's performance on the trial as either acceptable or unacceptable, wherein an acceptable performance is performance at or above the subject's acceptable performance threshold, and an unacceptable performance is performance below the subject's acceptable performance threshold; and reinforcing acceptable performance by selectively stimulating the subject's vagus nerve after completion of the acceptable performance.

Abstract: A distributed real-time wireless neural interface including a reader and an array of distinct recording devices having a wireless section and a sensor section. The reader outputs and receives radio-frequency signals. The wireless section of the array includes an rf power converter, an antenna, a regulator, and a modulator. The antenna receives the radio-frequency signals output by the reader and provides the radio-frequency signals to the rf power converter which converts such radio-frequency signals to power signals. The regulator receives the power signals and regulates such power signals to provide stable power signals. The sensor section receives the stable power signals and is adapted to detect neural activity and provide output signals containing information indicative of such neural activity to the modulator. The modulator receives the power signals and the output signals from the sensor section communicates the information in the output signals to the reader via the antenna.