Abstract: Systems and methods for deploying emergency roadside signaling devices are disclosed. In one aspect, a control system for an object placing device of an autonomous vehicle includes a processor, and a computer-readable memory in communication with the processor and having stored thereon computer-executable instructions to cause the processor to: receive a signal comprising instructions to activate the object placing device; and provide instructions to the object placing device to place a plurality of signaling devices in accordance with predetermined criteria.

Abstract: The invention relates to particular substituted heterocycle fused gamma-carbolines, their prodrugs, in free, solid, pharmaceutically acceptable salt and/or substantially pure form as described herein, pharmaceutical compositions thereof, and methods of use in the treatment of diseases involving the 5-HT2A receptor, the serotonin transporter (SERT), pathways involving the dopamine Di and D2 receptor signaling system, and/or the wopioid receptor.

Abstract: Novel compounds, compositions, and methods of using and preparing the same, which may be useful for treating alpha-1 antitrypsin deficiency (AATD).

Abstract: In embodiments, a mode selective optical fiber coupler may include a first propagation waveguide and a second propagation waveguide joined along a coupling length L. The first propagation waveguide and the second propagation waveguide may be tapered from an input face and an output face of the coupler to a midpoint of the coupler. An LP01 mode of an optical signal with a wavelength of 800-950 nm coupled into the first propagation waveguide propagates through the first propagation waveguide and is emitted from the first propagation waveguide. An LP01 loss of the coupler at the output face is less than 1.0 dB. An LP11 mode of the optical signal coupled into the first propagation waveguide is cross-coupled to the second propagation waveguide and is emitted from the second propagation waveguide. An LP11 loss of the coupler at the output face is less than 1.5 dB.

Abstract: This invention relates to an apparatus for conducting immunoassay test. The apparatus includes a groove unit having a groove along a vertical direction configured to hold a rod-shaped portion of a probe along the vertical direction, and a push pin configured to move along a horizontal direction, the push pin being capable of residing at a first position and a second position. A tip of the push pin is capable of pressing the rod-shaped portion of the probe against the groove when the push pin resides at the first position. The distance between the tip of the push pin and the groove is larger than a diameter of the rod-shaped portion of the probe when the push pin resides at the second position.

Abstract: A method of labeling a dataset includes inputting a testing set comprising a plurality of input data samples into a plurality of pre-trained machine learning models to generate a set of embeddings output by the plurality of pre-trained machine learning models. The method further includes performing an iterative cluster labeling algorithm that includes generating a plurality of clusterings from the set of embeddings, analyzing the plurality of clusterings to identify a target embedding with a highest duster quality, analyzing the target embedding to determine a compactness for each of the plurality of clusterings of the target embedding, and identifying a target cluster among the plurality of clusterings of the target embedding based on the compactness. The method further includes assigning pseudo-labels to the subset of the plurality of input data samples that are members of the target duster.

Abstract: Waveguides comprising materials with refractive index greater than or equal to 1.8 and methods of patterning waveguides are disclosed. Patterned waveguides comprising materials with refractive index greater than or equal to 1.8 can be incorporated in display devices, such as, for example wearable display devices to project virtual images to a viewer.

Abstract: Embodiments include a communication system including host computer, base station, and UE, and methods therein. The host computer provides user data and initiates a transmission carrying the user data to the UE via a cellular network comprising the base station. The UE receives, from the base station, an indication of an active bandwidth part (BWP), which is of size NBWP,1size in number of frequency-domain resource blocks (RBs). The UE receives an indication of one or more frequency-domain RBs assigned within the active BWP for carrying the user data. The indication is encoded based on a size NBWP,2size (<size NBWP,1size) of another BWP than the active BWP. The UE decodes the indication to obtain a starting virtual RB and a length of contiguously allocated RBs within the active BWP. The starting virtual RB is encoded with resolution K RBs, with K being based on a ratio of sizes NBWP,1size and NBWP,2size.

Abstract: In aspects, the invention provides novel compositions and methods for dominant inhibition of viral infection.

Abstract: Prostamide-containing biodegradable intraocular implants, prostamide compounds, prostamide-containing pharmaceutical compositions, and methods for making and using such implants and compositions for the immediate and sustained reduction of intraocular pressure and treatment of glaucoma in an eye of a patient are described.

Abstract: An apparatus and method for depositing a transition metal nitride film on a substrate by atomic layer deposition in a reaction space defined by an at least one chamber wall and showerhead is disclosed. The apparatus may include, a substrate support disposed within the reaction space, the substrate support configured for supporting at least one substrate and a temperature control system for controlling a temperature of the at least one chamber wall at those portions of the at least one chamber wall that is exposed to a vapor phase reactant. The apparatus may also include a temperature control system for controlling a temperature of the showerhead, wherein the temperature control system for controlling a temperature of the showerhead is configured to control the temperature of the showerhead to a temperature of between approximately 80° C. and approximately 160° C.

Abstract: First lithography and etching are carried out on a semiconductor structure to provide a first intermediate semiconductor structure having a first set of surface features corresponding to a first portion of desired fin formation mandrels. Second lithography and etching are carried out on the first intermediate structure, using a second mask, to provide a second intermediate semiconductor structure having a second set of surface features corresponding to a second portion of the mandrels. The second set of surface features are unequally spaced from the first set of surface features and/or the features have different pitch. The fin formation mandrels are formed in the second intermediate semiconductor structure using the first and second sets of surface features; spacer material is deposited over the mandrels and is etched back to form a third intermediate semiconductor structure having a fin pattern. Etching is carried out on same to produce the fin pattern.

Abstract: A method and system for obtaining an identifier from an item is disclosed. The method includes autonomously operating a robotic structure having a robotic arm to pick an item using an end effector of the robotic arm along a predetermined path from a source location to a destination location according to a plan. The picked item is moved according to the plan. An active measure is determined to be performed at least in part to obtain an identifier determined to be missing based on information received via the communication interface from one or more sensors. The robotic structure is autonomously operated to place the item at the destination location based at least in part on the plan.

Abstract: Susceptor assemblies having a susceptor base with a plurality of pockets formed in a surface thereof are described. Each of the pockets has a pocket edge angle in the range of 30 to 75° and a pocket edge radius in the range of 0.40±0.05 mm to 1.20 mm±0.05 mm. The pockets have a raised central region and an outer region that is deeper than the raised central region, relative to the surface of the surface of the susceptor base.

Abstract: The present invention is directed to cinnolinyl and quinolinyl pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

Abstract: A station (STA) configured for operation in a WLAN may perform bit scrambling on input bits to generate scrambled input bits and may perform probabilistic constellation shaping using a shaping encoder on the scrambled input bits. The shaping encoder may encode a segment of the scrambled input bits for a modulation order and generate a shaped bit stream. In these embodiments, the STA may generate a QAM symbol stream with a QAM modulator. The QAM symbol stream may be generated at least from the shaped bit stream and from parity bits using the modulation order. The STA may generate the parity bits from the shaped bit streams with a forward-error correction (FEC) encoder and may transmit the QAM symbol stream within a physical layer protocol data unit (PPDU). To address a potential byte boundary shift caused a decoding error at a receiving station, the STA may modify performance of the bit scrambling when probabilistic constellation shaping is performed.

Abstract: A station (STA) configured for operation in a wireless local area network (WLAN) may implement an unequal Modulation and Coding Scheme (MCS) for Probabilistic Constellation Shaping using first and second shaping encoders. The first shaping encoder may encode a first segment of input bits for a first modulation order and generate a first shaped bit stream and the second shaping encoder may encode a second segment of input bits for a second modulation order to generate a second shaped bit stream. A first QAM symbol stream may be generated at least from the first shaped bit stream and from parity bits using the first modulation order and a second QAM symbol stream may be generated at least from the second shaped bit stream and from parity bits using the second modulation order. The STA may generate the parity bits from the first and second shaped bit streams with one or more LDPC encoders and may transmit the first and second QAM symbol streams within a PPDU.

Abstract: For example, an apparatus may include a segment parser to parse scrambled data bits of a PPDU into a first plurality of data bits and a second plurality of data bits, the PPDU to be transmitted in an OFDM transmission over an aggregated bandwidth comprising a first channel in a first frequency band and a second channel in a second frequency band; a first baseband processing block to encode and modulate the first plurality of data bits according to a first OFDM MCS for transmission over the first channel in the first frequency band; and a second baseband block to encode and modulate the second plurality of data bits according to a second OFDM MCS for transmission over the second channel in the second frequency band.

Abstract: The disclosure provides methods the treatment of psychiatric disorders caused by viral, bacterial, or autoimmune encephalitis, and for treatment of psychiatric symptoms of viral, bacterial, and autoimmune encephalitis, and for protecting or reinforcing the blood-brain barrier, comprising administering to a patient in need thereof, a therapeutically effective amount of a 5-HT2A.

Abstract: A nonlinear radar system includes a first antenna configured to generate and emit an incident signal having a first frequency, a transponder tag attached to an existing portable object, wherein the transponder tag includes an electromagnetic nonlinear element configured to be detected by the incident signal. Upon being detected by the incident signal, the transponder tag is configured to transmit a reflected return harmonic signal having a second frequency different from the first frequency, wherein the reflected return harmonic signal is an on-off keying (OOK) signal. A second antenna is configured to receive the reflected return harmonic signal having the second frequency. The transponder tag includes a conductive layer in electrical communication with the electromagnetic nonlinear element including a Schottky diode.