Abstract: Methods and Systems for reducing or eliminating the optical noise in acquired images. In one embodiment, the method of this invention includes acquiring two images of an object, where, in each of the images, the object subtends a different angle and orientation with respect to a device utilized to acquire the image. Areas of optical noise are identified in each of the two images. The two images are combined in order to obtain areas of reduced optical noise in a composite image. The method can also include aligning the two images with each other and rendering the two images to a common scale. Systems of this invention implement the methods of this invention.