Abstract: A wearable device includes a support and a cushion that is coupled to the support, the cushion including a first portion and a second portion, the first portion having a first stiffness, the second portion having a second stiffness, and the first stiffness is at least four times greater than the second stiffness.

Abstract: Very high refractive index (n>2.2) lightguide substrates enable the production of 70° field of view eyepieces with all three color primaries in a single eyepiece layer. Disclosed herein are viewing optics assembly architectures that make use of such eyepieces to reduce size and cost, simplifying manufacturing and assembly, and better-accommodating novel microdisplay designs.

Abstract: Waveguides comprising materials with refractive index greater than or equal to 1.8 and methods of patterning waveguides are disclosed. Patterned waveguides comprising materials with refractive index greater than or equal to 1.8 can be incorporated in display devices, such as, for example wearable display devices to project virtual images to a viewer.

Abstract: Very high refractive index (n>2.2) lightguide substrates enable the production of 70° field of view eyepieces with all three color primaries in a single eyepiece layer. Disclosed herein are viewing optics assembly architectures that make use of such eyepieces to reduce size and cost, simplifying manufacturing and assembly, and better-accommodating novel microdisplay designs.

Abstract: The present disclosure relates to novel compounds that degrade Bruton's tyrosine kinase (BTK), pharmaceutical compositions containing such compounds, and their use in prevention and treatment of conditions modulated by BTK.

Abstract: Apparatuses, systems, and techniques to process image frames. In at least one embodiment, one or more neural networks are used to blend two or more video frames between a first video frame and a second video frame. In at least one embodiment, a blended video frame is used to generate an intermediate video frame between the first video frame and the second video frame.

Abstract: Embodiments are disclosed for one-to-many and many-to-many ranging using narrowband assisted (NBA)-multi-millisecond (MMS) ultra wideband (UWB) protocols. Some embodiments include an initiator device that communicates with many responder devices. For example, the initiator device can transmit a control/initialization poll message via NB signaling that identifies a ranging cycle, and transmit a first set of MMS segments corresponding to the control/initialization poll message. The initiator device can receive a plurality of report frames from two or more responder devices via NB signaling subsequent to transmitting the first set of MMS segments, and transmit within the ranging cycle, a ranging results report message based at least on the plurality of report frames via narrowband signaling.

Abstract: The disclosure provides sulfonamides based compounds and pharmaceutical compositions thereof, which are useful for inhibiting one or more mutations of EGFR, as well as methods for using such compounds to treat cancer associated with EGFR mutations.

Abstract: The present disclosure relates to novel compounds of Formula (I) that degrade Bruton's tyrosine kinase (BTK), pharmaceutical compositions containing such compounds, and their use in prevention and treatment of conditions modulated by BTK.

Abstract: The present disclosure relates to novel compounds that degrade Bruton's tyrosine kinase (BTK), pharmaceutical compositions containing such compounds, and their use in prevention and treatment of conditions modulated by BTK.

Abstract: An embodiment of the present application provides a temperature adaptive control circuit for a light emitting diode and a lighting and/or signaling apparatus. The control circuit includes: a light emitting diode load circuit unit in which one or more light emitting diodes are connected; and a temperature adaptive circuit unit comprising a positive temperature coefficient thermistor and a negative temperature coefficient thermistor connected in series, wherein the temperature adaptive circuit unit is configured such that current flowing through the one or more light emitting diodes in the light emitting diode load circuit unit is a function of sum of resistance of the positive temperature coefficient thermistor and resistance of the negative temperature coefficient thermistor. It not only can compensate the variation of the luminescent intensity with the temperature in a desired working temperature for the LEDs, but also can achieve overheating protection for the LEDs to avoid damage thereof.

Abstract: The present invention provides edible compositions comprising a sweet taste modulator or bitter taste blocker of the present invention, food products comprising such edible compositions and methods of preparing such food products. The present invention also provides methods of reducing the amount of sugar in a food product, methods of reducing the caloric intake in a diet, and methods of enhancing sweet taste or blocking a bitter taste in a food product.

Abstract: An embodiment of the present application provides a temperature adaptive control circuit for a light emitting diode and a lighting and/or signaling apparatus. The control circuit includes: a light emitting diode load circuit unit in which one or more light emitting diodes are connected; and a temperature adaptive circuit unit comprising a positive temperature coefficient thermistor and a negative temperature coefficient thermistor connected in series, wherein the temperature adaptive circuit unit is configured such that current flowing through the one or more light emitting diodes in the light emitting diode load circuit unit is a function of sum of resistance of the positive temperature coefficient thermistor and resistance of the negative temperature coefficient thermistor. It not only can compensate the variation of the luminescent intensity with the temperature in a desired working temperature for the LEDs, but also can achieve overheating protection for the LEDs to avoid damage thereof.

Abstract: Compounds of formula (I) including pharmaceutically acceptable salts, esters, solvates and stereoisomers thereof, R1, R2 and R3 are as defined herein. Pharmaceutical compositions containing a compound of structure (I), as well as methods relating to the use thereof, are also disclosed.

Abstract: The invention includes the fitted quaternary structure of insulin receptor. It also includes methods of identifying compounds that modulate insulin receptor activity by producing a compound that interacts with all or part of the fitted quaternary structure of insulin receptor or a fragment or derivative thereof and which thereby modulates insulin receptor activity.