Patents by Inventor Robert Martin Gale

Robert Martin Gale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transdermal administration of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methyl guanidines
    Publication number: 20040258742
    Abstract: Composition of matter for application to a body surface or membrane to administer a N-(2,5-Disubstituted phenyl)-N′-(3-substituted phenyl)-N′-methyl guanidine by permeation through the body surface or membrane, the composition comprising the guanidine compound to be administered, at a therapeutically effective rate, optionally in combination with a permeation enhancer or mixture. Also disclosed are drug delivery devices and methods for the transdermal administration of a guanidine for the prevention of neuropathic pain, neuropsychological deficits resulting from cardiac surgery (CABG), and other neurological disorders.
    Type: Application
    Filed: July 20, 2004
    Publication date: December 23, 2004
    Inventors: William Woodson Van Osdol, Robert Martin Gale, David Henry Brandwein, Rama Padmanabhan, Joan Sunram
  • Methods for transdermal drug administration
    Publication number: 20030215488
    Abstract: Adhesive transdermal drug delivery devices may be removed and subsequently reapplied to an area of skin if the adhesive has an initial adhesive/skin bond strength sufficient to maintain said transdermal drug delivery device on the skin to which it is applied for the entire predetermined administration period; and an adhesive/skin bond strength upon replacement on the skin after removal therefrom which is adequate to retain the device on the skin for the balance of the administration period.
    Type: Application
    Filed: June 3, 2003
    Publication date: November 20, 2003
    Inventor: Robert Martin Gale
  • Transdermal administration of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methyl guanidines
    Publication number: 20030198662
    Abstract: Composition of matter for application to a body surface or membrane to administer a N-(2,5-Disubstituted phenyl)-N′-(3-substituted phenyl)-N′-methyl guanidine by permeation through the body surface or membrane, the composition comprising the guanidine compound to be administered, at a therapeutically effective rate, optionally in combination with a permeation enhancer or mixture. Also disclosed are drug delivery devices and methods for the transdermal administration of a guanidine for the prevention of neuropathic pain, neuropsychological deficits resulting from cardiac surgery (CABG), and other neurological disorders.
    Type: Application
    Filed: April 11, 2003
    Publication date: October 23, 2003
    Inventors: William Woodson Van Osdol, Robert Martin Gale, David Henry Brandwein, Rama Padmanabhan, Joan Sunram
  • Methods for transdermal drug administration
    Patent number: 6348210
    Abstract: Adhesive transdermal drug delivery devices may be removed and subsequently reapplied to an area of skin if the adhesive has an initial adhesive/skin bond strength sufficient to maintain said transdermal drug delivery device on the skin to which it is applied for the entire predetermined administration period; and an adhesive/skin bond strength upon replacement on the skin after removal therefrom which is adequate to retain the device on the skin for the balance of the administration period.
    Type: Grant
    Filed: November 10, 1999
    Date of Patent: February 19, 2002
    Assignee: Alza Corporation
    Inventor: Robert Martin Gale
  • Methods for transdermal drug administration
    Publication number: 20020018805
    Abstract: Adhesive transdermal drug delivery devices may be removed and subsequently reapplied to an area of skin if the adhesive has an initial adhesive/skin bond strength sufficient to maintain said transdermal drug delivery device on the skin to which it is applied for the entire predetermined administration period; and an adhesive/skin bond strength upon replacement on the skin after removal therefrom which is adequate to retain the device on the skin for the balance of the administration period.
    Type: Application
    Filed: October 12, 2001
    Publication date: February 14, 2002
    Inventor: Robert Martin Gale