Patents by Inventor Robert Michelot

Robert Michelot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11214917
    Abstract: The present invention relates to a method of obtaining a solid material based on a polymer having its cellobiose units exhibiting the following characteristics: at least some of the cellobiose units have at least one carboxylic acid function attached to the C6 carbon, the other C6 carbons having a primary alcohol function attached thereto; and at least some of the cellobiose units have at least one of the two rings open between the C2 and C3 carbons, the other C2 and C3 carbons forming a ring and having an alcohol function attached thereto. Such a material, advantageously a textile, may be used as a compress.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: January 4, 2022
    Assignee: SYMATESE
    Inventors: Vithuy Dao, Robert Michelot, Benjamin Herbage, Fabien Fuchez, Eric Perouse
  • Publication number: 20190330794
    Abstract: The present invention relates to a method of obtaining a solid material based on a polymer having its cellobiose units exhibiting the following characteristics: at least some of the cellobiose units have at least one carboxylic acid function attached to the C6 carbon, the other C6 carbons having a primary alcohol function attached thereto; and at least some of the cellobiose units have at least one of the two rings open between the C2 and C3 carbons, the other C2 and C3 carbons forming a ring and having an alcohol function attached thereto. Such a material, advantageously a textile, may be used as a compress.
    Type: Application
    Filed: July 10, 2019
    Publication date: October 31, 2019
    Applicant: SYMATESE
    Inventors: Vithuy DAO, Robert MICHELOT, Benjamin HERBAGE, Fabien FUCHEZ, Eric PEROUSE
  • Publication number: 20160199538
    Abstract: Three-dimensional solid contractile collagen scaffolds having improved biological properties and electromechanical performance are provided. The scaffolds can be used for cell transplantation, including the fixation of biocompatible reagents and adhesion molecules which control cell adhesion, apoptosis, survival and/or differentiation simultaneously. Grafting adhesion molecules to the collagen matrices renders the scaffold suitable for use in vascular and cardiothoracic surgery/medicine, as well as in cell therapy for the heart and in artificial heart muscle engineering. Also, a method for grafting and optimizing the presentation of adhesion peptides or biological agents in the scaffold is provided.
    Type: Application
    Filed: February 9, 2016
    Publication date: July 14, 2016
    Inventors: Olivier SCHUSSLER, Robert MICHELOT
  • Patent number: 9289533
    Abstract: Materials and methods for improving the biological properties and electromechanical performance of collagen scaffolds used for cell transplantation, including the fixation of biocompatible reagents and adhesion molecules which control cell adhesion, apoptosis, survival and/or differentiation simultaneously. The grafting of adhesion molecules to collagen matrices renders same suitable for use in vascular and cardiothoracic surgery/medicine, as well as in cell therapy for the heart and in artificial heart muscle engineering. Also, a simple method for grafting and optimising the presentation of adhesion peptides or biological agents when the scaffold is made from collagen and/or contains accessible thiol, amine or carboxyl groups.
    Type: Grant
    Filed: June 10, 2008
    Date of Patent: March 22, 2016
    Inventors: Olivier Schussler, Robert Michelot
  • Publication number: 20150376457
    Abstract: The invention relates to a method for coating a surface, comprising: a step of bringing the surface into contact with a first composition comprising an amphiphilic compound; and a step of bringing same into contact with a second composition comprising a hydrophilic polymer.
    Type: Application
    Filed: January 31, 2014
    Publication date: December 31, 2015
    Applicant: NATVI SAS
    Inventor: Robert MICHELOT
  • Publication number: 20150147558
    Abstract: The present invention relates to a method of obtaining a solid material based on a polymer having its cellobiose units exhibiting the following characteristics: at least some of the cellobiose units have at least one carboxylic acid function attached to the C6 carbon, the other C6 carbons having a primary alcohol function attached thereto; and at least some of the cellobiose units have at least one of the two rings open between the C2 and C3 carbons, the other C2 and C3 carbons forming a ring and having an alcohol function attached thereto. Such a material, advantageously a textile, may be used as a compress.
    Type: Application
    Filed: June 3, 2013
    Publication date: May 28, 2015
    Applicant: SYMATESE
    Inventors: Vithuy Dao, Robert Michelot, Benjamin Herbage, Fabien Fuchez, Eric Perouse
  • Patent number: 8753664
    Abstract: A device including a body (12) including fibers without oxidized cellulose. The body (12) also includes fibers containing oxidized cellulose.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: June 17, 2014
    Assignee: Perouse Medical
    Inventors: Vithuy Dao, Robert Michelot, Eric Perouse
  • Publication number: 20120177719
    Abstract: A device including a body (12) including fibers without oxidized cellulose. The body (12) also includes fibers containing oxidized cellulose.
    Type: Application
    Filed: December 9, 2011
    Publication date: July 12, 2012
    Applicant: Perouse Medical
    Inventors: Vithuy Dao, Robert Michelot, Eric Perouse
  • Publication number: 20110046233
    Abstract: The present invention relates to compounds of general formula (1): in which, independently of each other, R1 and R2 represent: —OH, or —CH2—O—R3, or —CH2—S—R3, or R3, R4, R5 and R6 representing, independently of each other, —H or a carbon-containing group with 1 to 10 carbon atoms, saturated or unsaturated, optionally substituted with one or more heteroatomic groups. The invention also relates to pharmaceutical compositions containing these compounds, and their uses, in particular in the context of the treatment of cancer.
    Type: Application
    Filed: November 4, 2010
    Publication date: February 24, 2011
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (I.N.S.E.R.M.)
    Inventors: VI-THUY DAO, Jean De Gunzburg, Robert Michelot, Oliver Christophe De Mil
  • Patent number: 7851510
    Abstract: The present invention relates to compounds of general formula (1): in which, independently of each other, R1 and R2 represent: —OH, or —CH2—O—R3, or —CH2—S—R3, or R3, R4, R5 and R6 representing, independently of each other, —H or a carbon-containing group with 1 to 10 carbon atoms, saturated or unsaturated, optionally substituted with one or more heteroatomic groups. The invention also relates to pharmaceutical compositions containing these compounds, and their uses, in particular in the context of the treatment of cancer.
    Type: Grant
    Filed: January 6, 2005
    Date of Patent: December 14, 2010
    Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Institut National de la Sante et de la Recherche Medicale (I.N.S.E.R.M)
    Inventors: Vi-Thuy Dao, Jean De Gunzburg, Robert Michelot, Oliver Christophe De Mil
  • Publication number: 20100184183
    Abstract: Materials and methods for improving the biological properties and electromechanical performance of collagen scaffolds used for cell transplantation, including the fixation of biocompatible reagents and adhesion molecules which control cell adhesion, apoptosis, survival and/or differentiation simultaneously. The grafting of adhesion molecules to collagen matrices renders same suitable for use in vascular and cardiothoracic surgery/medicine, as well as in cell therapy for the heart and in artificial heart muscle engineering. Also, a simple method for grafting and optimising the presentation of adhesion peptides or biological agents when the scaffold is made from collagen and/or contains accessible thiol, amine or carboxyl groups.
    Type: Application
    Filed: June 10, 2008
    Publication date: July 22, 2010
    Inventors: Olivier Schussler, Robert Michelot
  • Publication number: 20090318566
    Abstract: The present invention relates to compounds of general formula (1): in which, independently of each other, R1 and R2 represent: —OH, or —CH2—O—R3, or —CH2—S—R3, or R3, R4, R5 and R6 representing, independently of each other, —H or a carbon-containing group with 1 to 10 carbon atoms, saturated or unsaturated, optionally substituted with one or more heteroatomic groups. The invention also relates to pharmaceutical compositions containing these compounds, and their uses, in particular in the context of the treatment of cancer.
    Type: Application
    Filed: January 6, 2005
    Publication date: December 24, 2009
    Inventors: Vi-Thuy Dao, Jean De Gunzburg, Robert Michelot, Oliver Christophe De Mil