Abstract: The applicator (1, 1?) of a cosmetic product (6) comprises a manual gripping means (2) and a means (3) of application of the said product (6), and is characterised in that: a) the said application means (3) comprises at least one fixed element (30) and one rotating element (31), forming an application roller free to rotate about the said fixed element (30) about a rotation axis (10), b) the said fixed element (31) is typically fixed to the said manual gripping means (2), c) the said fixed element (30) and the said rotating element (31) are fixed by reversible or irreversible cooperation. Advantages: easier application resulting in a different appearance.

Abstract: The applicator, typically an applicator of a cosmetic, includes a) an attachment element (2) designed to be temporarily and reversibly fixed to a finger (4) of a hand or end phalanx (40) of the finger (4), and b) an application member (3) fixed to the the temporary attachment element and chosen particularly as a function of the nature of the cosmetic to be applied, so as to form a digital applicator (1) of the cosmetic.

Abstract: The compact has a bottom, a cover, a hinge fixing the cover to the bottom, the cover and the bottom defining an average opening plane P of the compact, and forming a junction defining a closed external contour C in the plane P. The compact includes at least one bearing surface A on a typically horizontal plane support H defining a support surface or polygon S with area Ss, so as to have a compact with a “vertical” position. The contour C has a centre of gravity G forming a solid angle ? with the support surface S, with a minimum angle ?M typically varying from ?1=15° to ?2=60°, so as to simultaneously have a compact that is stable in the vertical position.

Abstract: The distributor-applicator mobile in the axial direction includes a body forming a cavity provided with an opening, and an applicator comprising a threaded cap forming a member for gripping the applicator, a rod and an application element: a) the body comprises a member for forming an axial partition in the cavity so as to form an axial sequence of N staged compartments in the cavity denoted C1 to CN, where N varies from 2 to 4, b) the forming member comprises N?1 separation elements being denoted Si between two successive compartments, c) each compartment Ci, where i>1, comprises a volume forming a storage element for the product, and a free volume forming a communication, such that the application element can access each compartment in order to collect the corresponding products.

Abstract: A product dispenser includes: a) a tubular body containing the product and a skirt open at its lower portion and closed at its upper portion by an arch equipped with at least one opening, b) a piston capable of sliding, in a leak-proof manner, inside the skirt, so as to compress the product, and force the passage of the product through the opening, and c) a cap designed to seal the opening, cooperating reversibly with the tubular body at its upper part or with said arch.

Abstract: Provided is a composition and a method for increasing cellular uptake of bioactive agents, particularly those compounds termed “small molecules” into the cells of mammalian tissue, such as the epithelial cells of the mucosa.

Abstract: The applicator includes a) a lower part for manually gripping the applicator, b) a central part for resiliently straining the applicator under a manual constraint, c) an upper part bearing an application material and d) an application material anchored to the upper part wherein: 1) the lower and central parts have mean visible cross-sections, denoted respectively SA and SB such that the relative deviation ER1=|SA?SB|/SA is less than 0.1, 2) the lower and central parts form a first longitudinal component having an axial direction and a first shape factor L/D between 3 and 7, L and D denoting respectively the largest axial length of and the largest diameter of the first component perpendicular to the axial direction.

Abstract: A distributor includes a body, typically provided with a lateral skirt and a bottom, and a cap, provided with an inner dome. The body includes at least one orifice for filling a cavity with the product, a device for closing the orifice, a device for attaching the product to the body, and a lower skirt forming a lower cavity with the bottom, capable of cooperating with the cap so as to form a system for stacking the distributor.

Abstract: The hollow body includes a sidewall and a supporting bottom. The body has a part, forming all or part of the bottom, free to move in the axial direction under a manual axial force applied thereon, due to a portion of the flexible wall surrounding the moving part and the thickness being chosen such that the flexible wall is resilient in bending. The flexible wall is an annular portion inscribed within a circle typically centred on the axial direction of the body. The body is formed from a plastic material that can be subjected to resilient bending. The axial manual pressure applied on the moving part enables reliable and repeated displacement thereof, and triggers a technical effect inside the hollow body, due to an auxiliary part.

Abstract: Applicator device (1) for a paste product, typically a cosmetic, typically intended to cooperate with a receptacle containing the paste product, contains a longitudinal body (2) with an axial direction (20), the longitudinal body (2) including an axial rod (3) and an applicator (4) fixed to the axial rod (3). The axial rod (3) is intended to cooperate with a manual gripping means of the applicator device (1), the applicator (4) is capable of sampling a fraction of the product contained in the receptacle, typically by cooperation of the applicator with a wiper, so that it can be applied on a support, usually a part of the body or the face when the product is a cosmetic.

Abstract: The wiper (1) intended to engage with a neck of a container intended to contain a fluid or paste cosmetic product includes a body (2) intended to be anchored to the neck, and a wiping element (3) anchored to the body (2). The wiping element (3) includes a resilient wall (4) which anchors the wiping element (3) to the body (2), the resilient wall (4) being able to distort when the applicator passes through, and to resume its so-called at rest shape after it has passed. The wiping element (3) includes a plurality of N typically vertical radial tongues (5) independent of each other, with N typically being between 4 and 20, typically integral with a peripheral skirt (6) of the wiping element (3).

Abstract: The compact (1) comprises a cover (2) fitted with a mirror (5) and provided with a first hinge portion (20), a hollow bottom (6) in which the said cosmetic products will be placed, the said bottom (6) being provided with a second hinge portion (60), a hinge (10) formed by cooperation of the said first and second hinge portions (20, 60), a magnetic closure (11) based on cooperation of an upper magnet (21) fixed to the cover (2) with a lower magnet (61) fixed to the said bottom (6) facing the upper magnet, and possibly an applicator of the said cosmetic product, and is characterised in that: a) the said cover (2) comprises a so-called upper wall (22) forming all or part of a means of attachment of the said upper magnet (21) to the said cover (2), the said upper wall (22) being typically located below the said upper magnet (21) so as to make the said upper magnet (21) invisible even when the said compact (1) is opened, b) the said bottom (6) comprises a so-called lower wall (62) forming all or part of the sa

Abstract: The dispenser-applicator includes a receptacle formed from a body and a distribution head having at least one orifice, and a cap that will close the head by screwing. The orifice includes a single orifice or a plurality of n orifices, not having any symmetry of revolution. The cap includes an outer shell carrying an internal thread and an inner sealing insert free to move in rotation with respect to the outer shell. The inner insert has a bottom carrying an axial projection capable of closing off the single orifice; the insert and the head cooperate during the screwing due to an orientation element, so as to automatically orient the insert with respect to the head so that the axial projection faces the orifice and closes it off.

Abstract: A case, includes a lid fitted with a first hinge portion, a concave bottom possibly including an inner frame intended to receive a trough containing the cosmetic product, the bottom or inner frame being fitted with a second hinge portion, the first and second hinge portions engaging to form a hinge, elements for closing the lid relative to the bottom or inner frame wherein: a) the closure elements include two magnets such that the lid is attracted towards the bottom inner frame for an opening angle ? below a maximum angle of opening ?L, b) the engagement is such that the maximum angle of opening ?L is between 20° and 90°, c) the magnets are fully or partially concealed.

Abstract: The invention in one embodiment relates to a case suitable for packaging a cosmetic product comprising: a lid optionally including a mirror, said lid being fitted with a first hinge element, a bottom optionally having an inner frame integral therewith, said lid and bottom forming a cavity intended to contain the cosmetic product or a trough containing the cosmetic product, the bottom being fitted with a second hinge element such that a hinge means is formed by engagement of the first and second hinge elements so as to allow rotation of the lid relative to the bottom along an axis of rotation, a fastening means for fastening and unfastening the lid relative to the bottom, wherein the case is capable of automatic opening in such a way that the lid opens automatically when force is exerted on the fastening means, and further wherein the hinge is formed by two half-hinges aligned along an axis of rotation, said half hinges including (i) a right-hand half-hinge D including two hinge half-portions D1 and D2 which e

Abstract: The case (1) comprises a cover (2) provided with a first hinge element (20) and a bottom (3) provided with a second hinge element (30), a hinge (4) being formed by cooperation between the said first (20) and second (30) hinge elements, a closer (5) comprising cooperation of a first closer element (21) fixed to the said cover (2), and a second closer element (31) fixed to the said bottom (3).

Abstract: A cosmetic product applicator, typically for mascara, includes a) a cap, typically threaded, b) a longitudinal stem in an axial direction, and c) a brush including an axial support and an application material securely attached to the support by means of a method of attachment, the application material typically forming a multitude of bristles or tufts of bristles, the longitudinal stem being securely attached, at its upper extremity, of the cap and, at its lower extremity, of the axial support of the brush. It is characterized in that the support is made of plastic including part or all of the means of attachment, and in that the application material includes a multitude of bristles or tufts of bristles.

Abstract: The distributor (1) intended to package a longitudinal stick product is provided with an axial propulsion mechanism (12) of the said longitudinal product, and comprises a) a cylindrical element called a “spiral” (2) provided with two helical grooves (20), b) a grooved tubular rod called a “guide” (3) with two opposed vertical grooves (30), c) a dish (4) acting as a support for the said longitudinal product, the said dish (4) comprising two pins (40), each radial pin (40) cooperating with a helical groove (20) through a vertical groove (30), and d) a means of closing off the upper opening of the distributor.

Abstract: Provided are methods of treating cancer, and/or the side effects of cancer therapy, involving the administration of glutamine, optionally in combination with a carbohydrate carrier that enhances the absorption of glutamine.

Abstract: The multiple applicator (1) includes a support (2) and a plurality of N specific cosmetic products applicators Ai (3), typically makeup applicators, solidarised to the said support. In this applicator (1): a) the said support (2) has a two-dimensional configuration comprising a central part (23) and a peripheral part (24) delimited by a border (20), each of the said N applicators being fixed to the said peripheral part (24), b) the said N specific applicators (3) are longitudinal applicators spaced along the said border (20), such that the said support (2) can be gripped manually between the fingers, c) the said support (2) has a maximum thickness E typically varying from 5 to 20 mm, so that it can typically be placed in a case. Advantageously these applicators, intended to be housed in a powder case, offer a wide variety of application possibilities in a very compact form, and advantageously replace the conventional powder puff.