Abstract: A computer-implemented system and method for detecting anomalies using sample-based rule identification is provided. Data for data is maintained analytics in a database. A set of anomaly rules is defined. A rare pattern in the data is statistically identified. The identified rare pattern is labeled as at least one of anomaly and non-anomaly based on verification by a domain expert. The set of anomaly rules is adjusted based on the labeled anomaly. Other anomalies in the data are detected and classified by applying the adjusted set of anomaly rules to the data.

Abstract: An engine assembly includes a small air-cooled engine and a dry sump lubrication system including an external oil reservoir, wherein the dry sump lubrication system has an overall oil capacity that provides at least five hundred hours of engine oil life.

Abstract: In an apparatus for collecting aerosolised respirable particles of an inhalable medicinal formulation, aerosolised formulation is drawn pneumatically through a dose collection section comprising an inlet orifice (201) and an air-permeable filter (206), the filter being positioned opposed to said orifice, and extending across the pathway (4) for filtering the pneumatic flow so as to retain particulate material therein on the filter, and the orifice (201) being so dimensioned and configured that it has an unimpeded area that is no less than 75% of the area of the filter (201) on which the dose will be collected. In a method using the apparatus, particles (209, 210) collected on the filter may optionally be subjected to a dissolution test. A good correlation is obtainable between in vitro and in vivo doses with improved independence of loading.

Abstract: A method 100 to produce one or more diene molecules 135 including steps of preparing a biomass hydrolysate 137 from biomass, producing an engineered organism 120 that can feed on the biomass hydrolysate and express an alcohol product useful to make the diene molecule, fermenting 115 the broth with the engineered organism, separating 125 the alcohol product from fermentation broth, and catalyzing 130 the alcohol to create the diene molecule.

Abstract: A compression-release brake system is provided that includes a lost motion exhaust rocker assembly, an actuation piston, and a reset device. The actuation piston includes an actuation piston body that is slidably received by the rocker arm to define a piston cavity in the rocker arm and is movable between piston retracted and extended positions. The actuation piston is configured to be operatively associated with the exhaust valve to permit unseating of the exhaust valve from the seated state. An actuation piston check valve is configured to move between closed and open positions to permit hydraulic fluid flow through an actuation piston communication port to the piston cavity. The reset device includes a reset check valve and a reset pressure control spring for applying a biasing force to the reset check valve to urge the reset check valve toward an open position.

Abstract: A flight plan analysis system is configured to determine a flight plan decision regarding a proposed flight plan for an unmanned aerial vehicle (UAV). The flight plan analysis system includes a flight plan database that stores risk factor data, and a flight plan analysis unit communicatively coupled to the flight plan database. The flight plan analysis unit receives a proposed flight plan for the UAV and determines the flight plan decision based on an analysis of the proposed flight plan and the risk factor data.

Abstract: An engine assembly includes an air-cooled engine and an external oil reservoir. The engine includes a vertically-oriented crankshaft a crankcase cover having a front portion and a rear portion, wherein the front portion of the crankcase cover and the cylinder head are located forward of a vertical plane that includes the crankshaft axis, a return pump housing formed in the exterior of the crankcase cover, a return pump positioned in the return pump housing, and a return pump inlet formed through the crankcase cover, wherein the return pump inlet is located in the front portion of the crankcase cover and the return pump inlet is located closer to the camshaft than to the crankshaft. The external oil reservoir includes an oil tank and an oil filter assembly.

Abstract: A flight range-restricting system is configured to control a flight range of an unmanned aerial vehicle (UAV). The flight range-restricting system includes a database including a UAV capabilities storage area that stores UAV capabilities data indicative of technical specifications of the UAV, and a restricted airspace storage area that stores restricted airspace data indicative of a restricted airspace. A range-restricting control unit is communicatively coupled to the database. The range-restricting control unit controls the flight range of the UAV based on a current location of the UAV, the UAV capabilities data, and the restricted airspace data.

Abstract: A hydraulic device can include two or more rings, a rotor having a plurality of vanes, and an adjuster. The two or more rings can be rotatably mounted within the hydraulic device and arranged adjacent one another configured for relative rotation with respect to one another. The rotor can be disposed for rotation about an axis within the two or more rings and can have a plurality of circumferentially spaced slots, each slot having at least one of the plurality of vanes located therein. The plurality of vanes can be configured to be movable between a retracted position and an extended position where the plurality of vanes work a hydraulic fluid introduced adjacent to the rotor. The adjuster can be configured to translate linearly to rotatably position the two or more rings relative to one another to increase or decrease a displacement of the hydraulic fluid between the rotor and the two or more rings.

Abstract: An engine assembly includes an engine, an external oil reservoir, a supply pump, and a return pump. The engine includes an oil gallery configured to distribute oil and a crankcase chamber. The external oil reservoir includes an oil tank defining an oil chamber and an oil filter assembly including a housing at least partially defining a filter chamber, and a filter positioned within the filter chamber. The supply pump is in fluid communication with the oil chamber and the oil gallery and the supply pump is configured to draw oil from the oil chamber and provide pressurized oil to the oil gallery. The return pump in fluid communication with the crankcase chamber and the filter chamber and the return pump is configured to draw oil from the crankcase chamber and provide pressurized oil to the filter chamber.

Abstract: A compression-release brake system is provided that includes a lost motion exhaust rocker assembly, an actuation piston, and a reset device. The actuation piston includes an actuation piston body that is slidably received by the rocker arm to define a piston cavity in the rocker arm and is movable between piston retracted and extended positions. The actuation piston is configured to be operatively associated with the exhaust valve to permit unseating of the exhaust valve from the seated state. An actuation piston check valve is configured to move between closed and open positions to permit hydraulic fluid flow through an actuation piston communication port to the piston cavity. The reset device includes a reset check valve and a reset pressure control spring for applying a biasing force to the reset check valve to urge the reset check valve toward an open position.

Abstract: Various vehicle systems capable of different operation modes are disclosed. According to one example, the system can include at least one input shaft, at least one output shaft, a plurality of hydraulic devices, and one or more accessories. The plurality of hydraulic devices can be configured to be operable as vane pumps in a retracted vane mode of operation and can be configured to be operable as a hydraulic couplings to couple the at least one input shaft with the at least one output shaft in a vane extended mode of operation. The plurality of hydraulic devices can be simultaneously operable as the hydraulic couplings and the vane pumps. The one or more accessories can be in fluid communication with the plurality of hydraulic devices and can be configured to receive a hydraulic fluid pumped from one or more the plurality of hydraulic devices when operating as the vane pumps.

Abstract: A compression-release brake system is provided that includes a lost motion exhaust rocker assembly, an actuation piston, and a reset device. The actuation piston includes an actuation piston body that is slidably received by the rocker arm to define a piston cavity in the rocker arm and is movable between piston retracted and extended positions. The actuation piston is configured to be operatively associated with the exhaust valve to permit unseating of the exhaust valve from the seated state. An actuation piston check valve is configured to move between closed and open positions to permit hydraulic fluid flow through an actuation piston communication port to the piston cavity. The reset device includes a reset check valve and a reset pressure control spring for applying a biasing force to the reset check valve to urge the reset check valve toward an open position.

Abstract: A compression-release brake system is provided that includes a lost motion exhaust rocker assembly, an actuation piston, and a reset device. The actuation piston includes an actuation piston body that is slidably received by the rocker arm to define a piston cavity in the rocker arm and is movable between piston retracted and extended positions. The actuation piston is configured to be operatively associated with the exhaust valve to permit unseating of the exhaust valve from the seated state. An actuation piston check valve is configured to move between closed and open positions to permit hydraulic fluid flow through an actuation piston communication port to the piston cavity. The reset device includes a reset check valve and a reset pressure control spring for applying a biasing force to the reset check valve to urge the reset check valve toward an open position.

Abstract: A vehicle floor mat is provided for placement on a vehicle floor having surface irregularities, and includes a floor mat body having an upper surface, a peripheral edge, and a bottom surface. The bottom surface has an integral depending support structure provided with a variable height such that the shape of the support structure complements the irregularities in the vehicle floor. Upon the vehicle floor mat being placed on the vehicle floor, said support structure engages the irregularities and upper floor mat surface is generally level.

Abstract: A plastic injection molded part is provided, including a first portion having a front surface and a rear surface, the front surface including border formations defining a space, and having at least one bleed hole in communication with said rear surface; and a second portion disposed within the space defined by the border formations and including areas filling the at least one bleed hole, such that when the part is formed, molten plastic forming the second portion enters the space through at least one bleed hole.

Abstract: The present invention relates to a simple, robust and effective process for preparing a dry powder inhalation formulation containing at least one drug, preferably a highly active drug, more preferably Tiotropium bromide or Tiotropium bromide monohydrate, and a lactose carrier. The process is characterized in that a three-layered composition containing a drug layer in between layers of the lactose carrier is mixed and the obtained preblend is mixed with additional lactose carrier. The process combines a simple manufacturing procedure with an excellent content uniformity obtained over a wide range of mixing parameters.

Abstract: A steam generator apparatus for generating steam from a feedwater inlet stream including impurities is disclosed. The apparatus includes a tubing circuit in communication with an inlet for receiving the feedwater stream, the tubing circuit having a substantially unrifled bore defined by a metal wall, and a heat source operable to deliver a heat flux to the feedwater stream through the metal wall of the tubing circuit, the heat flux being operable to cause evaporation of feedwater within the tubing circuit and to produce an outlet stream at an outlet of the tubing circuit, the outlet stream includes a steam portion and liquid phase portion, the steam portion being greater than about 80% of the outlet stream by mass, the steam portion providing sufficient cooling of the metal wall to maintain a wall temperature at less than a threshold temperature associated with safe operation of the steam generator apparatus.

Abstract: A process for the production of particles comprises the steps of formation of a solution of a desired substance in a suitable solvent; ii) generation of an aerosol from the solution of said substance; iii) collection of the aerosol droplets in a vessel containing a non-solvent of said substance; and iv) the application of ultrasound to the droplets dispersed in the non-solvent to effect crystallisation of said substance. The particles produced find application in for example pharmaceutical and agrochemical formulations, especially in inhalation formulations.

Abstract: An engine assembly includes an engine, an external oil reservoir, a supply pump, and a return pump. The engine includes an oil gallery configured to distribute oil and a crankcase chamber. The external oil reservoir includes an oil tank defining an oil chamber and an oil filter assembly including a housing at least partially defining a filter chamber, and a filter positioned within the filter chamber. The supply pump is in fluid communication with the oil chamber and the oil gallery and the supply pump is configured to draw oil from the oil chamber and provide pressurized oil to the oil gallery. The return pump in fluid communication with the crankcase chamber and the filter chamber and the return pump is configured to draw oil from the crankcase chamber and provide pressurized oil to the filter chamber.