Abstract: A supervised learning processing (SLP) system and non-transitory, computer program product provides cooperative operation of a network of supervised learning processors to concurrently distribute supervised learning processor training, generate predictions, and provide prediction driven responses to input objects, such as NL statements. The SLP system includes SLP stages that are distributed across multiple SLP subsystems. Concurrently training SLP's provides accurate predictions of input objects and responses thereto, the SLP system and non-transitory, computer program product enhance the network by providing high quality value predictions and responses and avoiding potential training and operational delays. The SLP system can enhance the network of SLP subsystems by providing flexibility to incorporate multiple SLP models into the network and train at least a proper subset of the SLP models while concurrently using the SLP system and non-transitory, computer program product in commercial operation.

Abstract: The present invention relates to methods for the differentiating, diagnosing, and treating Lyme disease in a subject. The methods according to the invention are characterized by the detection of a biomarker signature capable of differentiating Lyme disease from like-symptom diseases, the biomarker signature being comprised of a combination of two or more analytes.

Abstract: The present invention relates to methods for the diagnosing, prognosing, monitoring, differentiating, treating, and managing of Lyme disease in a subject. The methods according to the invention are characterized by the detection of a biomarker signature comprised of a combination of two or more analytes indicative of disease.

Abstract: The present invention relates to methods for the diagnosing, prognosing, monitoring, differentiating, treating, and managing of Lyme disease in a subject. The methods according to the invention are characterized by the detection of a biomarker signature comprised of a combination of two or more analytes indicative of disease.

Abstract: The present invention relates to methods for the diagnosing, prognosing, monitoring, differentiating, treating, and managing of Lyme disease in a subject. The methods according to the invention are characterized by the detection of a biomarker signature comprised of a combination of two or more analytes indicative of disease.

Abstract: The present invention relates to methods for the differentiating, diagnosing, and treating Lyme disease in a subject. The methods according to the invention are characterized by the detection of a biomarker signature capable of differentiating Lyme disease from like-symptom diseases, the biomarker signature being comprised of a combination of two or more analytes.

Abstract: A supervised learning processing (SLP) system and non-transitory, computer program product provides cooperative operation of a network of supervised learning processors to concurrently distribute supervised learning processor training, generate predictions, and provide prediction driven responses to input objects, such as NL statements. The SLP system includes SLP stages that are distributed across multiple SLP subsystems. Concurrently training SLP's provides accurate predictions of input objects and responses thereto, the SLP system and non-transitory, computer program product enhance the network by providing high quality value predictions and responses and avoiding potential training and operational delays. The SLP system can enhance the network of SLP subsystems by providing flexibility to incorporate multiple SLP models into the network and train at least a proper subset of the SLP models while concurrently using the SLP system and non-transitory, computer program product in commercial operation.

Abstract: The present invention relates to methods for the diagnosing, prognosing, monitoring, differentiating, treating, and managing of Lyme disease in a subject. The methods according to the invention are characterized by the detection of a biomarker signature comprised of a combination of two or more analytes indicative of disease.

Abstract: A method and apparatus for inserting a watermark into a compiled computer program. A location process specifies an insertion point in the compiled program and a watermark generating process inserts a watermark, based on data to be encoded, into the program at the insertion point. The location process is also utilized to specify the location of watermark data to be decoded.

Abstract: A Novel is a written fictional story that hopefully gives the reader a joyful reading experience with the ability to visualize the story depending on the author's expertise. As the story unfolds, with the storyteller's power of the written word, in describing and relating the story's plot and associated scenes that produce images of the characters and of the scenes pictured in the mind of reader. The present invention provides the methodology to apply advanced computer technology that will transform a complete written work to create a computer generated 3-D animated motion picture. A staff of computer operator/designers will be able to process the work to achieve the computer-produced “Novel's Cinematization” [NC].

Abstract: A method for detecting one or more metabolites of a test agent in a tissue including: A) incubating a test agent and an enzyme within a three-dimensional structure comprising a first mold or polymer scaffold, a semi-permeable membrane, and a second mold or polymer scaffold, wherein the semi-permeable membrane is disposed between the first and second molds or polymer scaffolds, and wherein the first mold or polymer scaffold has microchannels that form a fluidic branching network that mimics the forces and transport of natural vasculatures and wherein the second mold or polymer scaffold comprises cells; B) forming an enzyme-substrate complex between the enzyme and the test agent; and C) detecting one or more metabolites of the test agent.

Abstract: The present invention generally relates to a combination of the fields of tissue engineering, drug discovery and drug development. It more specifically provides new methods and materials for testing the efficacy and safety of experimental drugs, defining the metabolic pathways of experimental drugs and characterizing the properties (e.g., side effects, new uses) of existing drugs. Preferably, evaluation is carried out in three-dimensional tissue-engineered systems, wherein drug toxicity, metabolism, interaction and/or efficacy can be determined.

Abstract: A method of determining toxicity of a test agent in a tissue including A) incubating a test agent within a three-dimensional tissue engineered structure comprising a first mold or polymer scaffold, a semi-permeable membrane, and a second mold or polymer scaffold, wherein the semi-permeable membrane is disposed between the first and second molds or polymer scaffolds, and wherein the first mold or polymer scaffold has microchannels comprising vessels that bifurcate, and B) obtaining information from step A) to assess toxicity.

Abstract: Aspects for consumer product distribution in the embedded system market are described. The aspects include forming a secure network for distributing product digitation files capable of configuring operations of an adaptive computing engine (ACE), and providing an agent server within the secure network for controlling licenses of the product digitation files, wherein a separation of responsibility and control of the distributing and licensing exists.

Abstract: A rapid electrochemical flow-through sensor and method for detecting the presence of autoantibodies in a fluid sample such as blood is shown and described. The sensor may take either a single- or multi-plexed form. The sensor comprises a fluid inlet, a reaction region comprising immobilized autoantigens and an electrode assembly, and a fluid outlet.

Abstract: A system and apparatus for inserting a watermark into a compiled computer program selectively replaces specified optimizations by non-optimized code to encode bit values of the watermark. The watermark is read by decoding the executable code and assigning the decoded bit values, determined by the presence or absence of optimized code, to bit positions in a signature.

Abstract: The present invention generally relates to a combination of the fields of tissue engineering, drug discovery and drug development. It more specifically provides new methods and materials for testing the efficacy and safety of experimental drugs, defining the metabolic pathways of experimental drugs and characterizing the properties (e.g., side effects, new uses) of existing drugs. Preferably, evaluation is carried out in three-dimensional tissue-engineered systems, wherein drug toxicity, metabolism, interaction and/or efficacy can be determined.

Abstract: A system and method for information distribution and retrieval. A preferred embodiment comprises downloading information, such as data, an application, and the like, from a server to a client. The information may be distributed to other clients without the need of a network connection to the server. Furthermore, modifications to the information made by the client may be distributed to other clients and the server. In another embodiment, the present invention downloads segments on an as needed basis. The segments may be reusable to provide further benefits. A relatively small application utilizes the reusable segments and an activity graph to perform specific functions.

Abstract: Aspects for structuring consumer product distribution in the embedded system market that allows for increased revenue potential are described. The aspects include establishing a secure network with a number of control points for distributing product digitation files capable of configuring operations of an adaptive computing engine (ACE), and utilizing the control points as revenue generation events during the distributing.

Abstract: Aspects for consumer product distribution in the embedded system market are described. The aspects include forming a secure network for distributing product digitation files capable of configuring operations of an adaptive computing engine (ACE), and providing an agent server within the secure network for controlling licenses of the product digitation files, wherein a separation of responsibility and control of the distributing and licensing exists.