Patents by Inventor Robert S. Hillman
Robert S. Hillman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9897618Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.Type: GrantFiled: December 3, 2015Date of Patent: February 20, 2018Assignee: C A Casyso GmbHInventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
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Publication number: 20160091483Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.Type: ApplicationFiled: September 29, 2014Publication date: March 31, 2016Inventors: Cory Lee McCluskey, Robert S. Hillman, Michael Gorin, Hubert Martin Schwaiger
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Publication number: 20160091515Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.Type: ApplicationFiled: December 3, 2015Publication date: March 31, 2016Inventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
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Publication number: 20160091517Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.Type: ApplicationFiled: December 3, 2015Publication date: March 31, 2016Inventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
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Publication number: 20160091514Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.Type: ApplicationFiled: December 3, 2015Publication date: March 31, 2016Inventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
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Publication number: 20160091516Abstract: Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.Type: ApplicationFiled: December 3, 2015Publication date: March 31, 2016Inventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey, Hubert Martin Schwaiger
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Publication number: 20100036310Abstract: An integrated patient monitoring and control system is provided which includes a sample set, the sample set being adapted for coupling to the patient to obtain a specimen from the patient, a sensor, the sensor being adapted to receive the specimen from the sample set and to analyze the sample, a medication control unit, the medication control unit receiving information from the sensor, and utilizing that information to determine medication dosing information for the patient, and a medication administration system, the medication administration system receiving the dosing information from the medication control unit, and adapted to cause administration of the medication to the patient. If the sample set is adapted for blood draw, the system advantageously is performed in conjunction with a pneumatic pressure cuff, inflated so as to aid in blood draw.Type: ApplicationFiled: August 3, 2009Publication date: February 11, 2010Inventor: ROBERT S. HILLMAN
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Patent number: 5922551Abstract: Methodology which avoids the problems associated with interference from whole blood is provided for instrumented determination of platelet binding function. Particularly, small particles to which fibrinogen is bound, and which contain an infrared light absorbing dye, are used to determine the binding of platelets in a whole blood sample to the fibrinogen. Agglutination of the platelets with the coated particles is determined by a change in infrared light absorption characteristics.Type: GrantFiled: March 20, 1997Date of Patent: July 13, 1999Assignee: Accumetrics, Inc.Inventors: Dennis A. Durbin, Theodore T. Lee, Boris I. Ratnikov, Robert S. Hillman, Jeffrey W. Smith
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Patent number: 5733259Abstract: A closed-loop drug delivery system uses patient response and rule based decision making methods to achieve operator specified responses for diagnostic purposes. In the preferred embodiment, cardiac diagnosis is performed by pharmacologically stressing the heart by administration of an exercise simulating agent drug. In the preferred method, a protocol is defined, which preferably includes a target for a physiologic variable, such as heart rate, and a plan to achieve that target value. Preferably, the plan includes a specification of the desired rate of increase in that variable, such as the rate of increase in the heart rate per minute. The plan comprises the desired changes in the physiologic variable as a function of time. While any desired function may be used, the more common modes include RAMP, HOLD, LEVEL and TARGET mode. In one aspect of this invention, the protocol may be varied by the operator after drug administration has begun.Type: GrantFiled: December 22, 1994Date of Patent: March 31, 1998Assignee: Gensia Pharmaceuticals, Inc.Inventors: Christian P. Valcke, Walter J. Bochenko, Robert S. Hillman
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Patent number: 5697899Abstract: A feedback controlled drug delivery system includes automated blood sampling and analysis and dosing of the patient. Automated sampling is performed by direct analysis of patient blood, such as for measurement of its coagulation state. A novel manifold includes a fluid input port, a patient port adapted to output fluid and to receive a blood sample from the patient, and a fluid pathway connecting the fluid port and the patient port. A sample line is connected to the fluid pathway to provide the sample to an analyzer. In one aspect of this invention, the sample is forced through the sample line by isolating the patient port, such as by a valve, and non-drug fluid is forced into the manifold causing the blood to cross through the sample line. Alternately, a pump force may be utilized on the sample line. In another aspect of this invention, a positive interlock system is utilized between a drug source and the system.Type: GrantFiled: February 7, 1995Date of Patent: December 16, 1997Assignee: GensiaInventors: Robert S. Hillman, Christian P. Valcke, Robert T. Gauthier
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Patent number: 5383848Abstract: Methods, formulations, and a system for improved iontophoretic administration of a drug, by, preferably, topical administration of a formulation containing an active vasodilator, rubefacient, or counterirritant agent such as capsaicin on the skin at the electrode site, or, iontophoretic administration of a vasodilator formulation or alpha blocker prior to iontophoretic administration of the drug.Type: GrantFiled: April 4, 1991Date of Patent: January 24, 1995Assignee: Gensia, Inc.Inventors: Robert S. Hillman, John M. Pawelchak
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Patent number: 5300779Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.Type: GrantFiled: August 18, 1992Date of Patent: April 5, 1994Assignee: Biotrack, Inc.Inventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
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Patent number: 5204525Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.Type: GrantFiled: July 19, 1991Date of Patent: April 20, 1993Assignee: BiotrackInventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
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Patent number: 5164598Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.Type: GrantFiled: February 5, 1991Date of Patent: November 17, 1992Assignee: BiotrackInventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
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Patent number: 5144139Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.Type: GrantFiled: July 19, 1991Date of Patent: September 1, 1992Assignee: Biotrack, Inc.Inventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
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Patent number: 5140161Abstract: Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastics devices is also described along with various control devices for use with the basic device.Type: GrantFiled: July 23, 1991Date of Patent: August 18, 1992Assignee: BiotrackInventors: Robert S. Hillman, Michael E. Cobb, Jimmy D. Allen, Ian Gibbons, Vladimir E. Ostoich, Laura J. Winfrey
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Patent number: 5135719Abstract: A method for separating plasma from red blood cells and a device utilizing the method in which a low-pressure filter is interposed in a pathway between an inlet port and a reaction area. The sole driving force for the movement of plasma from the filter to the reaction area is capillary force provided by a tubular capillary. The filter is selected from glass microfiber filters of specified characteristics, which can operate in the absence of agglutinins, and filters capable of separating agglutinated red cells from plasma, which require the use of an agglutinin.Type: GrantFiled: October 23, 1990Date of Patent: August 4, 1992Assignee: Biotrack, Inc.Inventors: Robert S. Hillman, Ian Gibbons
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Patent number: 5088978Abstract: An apparatus and method for iontophoretic transdermal delivery of exercise simulating agents includes an electrode having disposed therein a drug reservoir comprising a viscosity-control agent comprising an aqueous sol with an antioxidant, a preservative, a chelator and a buffer. A silver/silver chloride conducive element is preferably situated in the electrode adjacent the drug reservoir to conduct an electric charge across the reservoir.Type: GrantFiled: January 26, 1990Date of Patent: February 18, 1992Assignee: Gensia Pharmaceuticals, Inc.Inventors: Robert S. Hillman, John M. Pawelchak
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Patent number: 5077017Abstract: A dilution and mixing cartridge comprising a sample application site, a mixing chamber in fluid receiving relationship to the sample application site, a diluent application site in fluid donating relationship to the mixing chamber, a first valve means selectively preventing flow from the diluent application site to the mixing chamber, and a mixture isolating chamber hydrostatically connected to the mixing chamber is provided along with a method for using this cartridge to sequentially dilute a sample with the same or different diluents.Type: GrantFiled: November 5, 1987Date of Patent: December 31, 1991Assignee: Biotrack, Inc.Inventors: Michael M. Gorin, Robert S. Hillman, Ian Gibbons, Michael E. Cobb
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Patent number: D777343Type: GrantFiled: May 28, 2015Date of Patent: January 24, 2017Assignee: C A Casyso AGInventors: Michael Gorin, Robert S. Hillman, Cory Lee McCluskey