Abstract: Novel dry powder compositions comprising and methods relating thereto are provided. The dry powder compositions comprise PDE5 inhibitors, such as vardenafil, or pharmaceutically acceptable salts or esters thereof. The dry powder compositions may optionally include an carrier/excipient. The concentration of active agent may be at least about 2% by weight. Methods of aerosolizing the dry powder compositions and using them to treat various diseases are also disclosed.

Abstract: Novel dry powder compositions comprising and methods relating thereto are provided. The dry powder compositions comprise PDE5 inhibitors, such as vardenafil, or pharmaceutically acceptable salts or esters thereof. The dry powder compositions may optionally include an carrier/excipient. The concentration of active agent may be at least about 2% by weight. Methods of aerosolizing the dry powder compositions and using them to treat various diseases are also disclosed.

Abstract: A trackball rotates a three-dimensional image displayed by a computer. Displacement data is generated for designated first and second non-antipodal points on the surface of the trackball's roller ball, for displacement of the designated first and second points during a time interval between a starting time and an ending time. The displacement data is used to generate a rotational transformation that is representative of a change in rotational orientation of the roller ball occurring during the time interval. The generated transformation is then applied to the displayed computer image to cause the image to be rotated around an image pivot point in correspondence with the rotation of the roller ball around its center.

Abstract: An apparatus and method for motivating students in mathematics education, computer technology education and information encoding. The apparatus consists of a container holding multi-state sources and a reading device, if necessary, that can determine the state of the sources in the container when it is closed. Students determine the states of the sources and use a predetermined algorithm to determine the information or data represented in the container. The apparatus and method can be presented to an audience as a magic trick.

Abstract: We have developed a chicken (Gallus domesticus) Z-chromosome-specific DNA library in a phage vector, by means of chromosome microisolation and microcloning. The chromosomal origin, specificity and purity was evaluated by fluorescent in situ hybridization (FISH) on chicken metaphases. Heterologous chromosome painting, using this Z-chromosome-specific probe on turkey (Meleagris gallopavo) metaphases identified its homologous Z-chromosome, under the same stringent conditions as that used in the chicken, indicating a high degree of Z-chromosome sequence homology among these two species. This chicken Z-chromosome library will facilitate the development of Z-chromosome-specific DNA markers that will be useful for genetic mapping in the domestic chicken and related avian species. The Z-chromosome-specific DNA probe will also be useful for studies pertaining to the sex chromosome evolution in avian species.