Abstract: The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the number of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment; and when reconstituted, has reduced complement activation (C5A, C3A).

Abstract: The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the mean size of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment.

Abstract: The spray dried plasma by the nature of its characteristics and the process by which it is made allows for a dried plasma with reduced pathogens. It has at least three aspects of pathogen reduction that results in a plasma product with reduced or no pathogens. The first aspect relates to a spray drying disposable and machine that eliminates or minimizes the introduction of pathogens into the spray drying process and is referred to as the anti-contamination process. The second aspect of pathogen reduction relates to the spray drying process and parameters that reduces pathogens that may be present in the donor plasma, and/or inhibit pathogen growth and/or pathogen proliferation introduced by the donor plasma. The third aspect results in reduced pathogens occurring during storage of the dried plasma wherein the manufacturing and storage conditions are such that pathogens are reduced, and/or pathogen growth and/or pathogen proliferation are inhibited.

Abstract: The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the number of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment; and when reconstituted, has reduced complement activation (C5A, C3A).

Abstract: A sensor arrangement (46) for an automated transmission includes multiple axially parallel shift rails (4, 14, 24, 34) being axially displaceable by associated shift actuators (8, 18, 28, 38). The sensor arrangement (46) has multiple displacement sensors (48, 56, 64, 72) made up of a signal transmitter (50, 58, 66, 74) attached to a shift rail and a signal receiver (52, 60, 68, 76) fixedly arranged on a housing. The signal transmitters are in the form of a permanent magnet, and the signal receivers are in the form of a 3D Hall sensor. To detect an external magnetic interference field, which can corrupt the sensor signals from the displacement sensors (48, 56, 64, 72), the signal transmitters (50, 58, 66, 74) have identical axial alignments of their magnetic poles, and the signal receivers (52, 60, 68, 76) are in a common plane (80) that is horizontal in their installation position.

Abstract: The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the number of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment; and when reconstituted, has reduced complement activation (C5A, C3A).

Abstract: The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the number of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment; and when reconstituted, has reduced complement activation (C5A, C3A).

Abstract: A sensor arrangement (46) for an automated transmission includes multiple axially parallel shift rails (4, 14, 24, 34) being axially displaceable by associated shift actuators (8, 18, 28, 38). The sensor arrangement (46) has multiple displacement sensors (48, 56, 64, 72) made up of a signal transmitter (50, 58, 66, 74) attached to a shift rail and a signal receiver (52, 60, 68, 76) fixedly arranged on a housing. The signal transmitters are in the form of a permanent magnet, and the signal receivers are in the form of a 3D Hall sensor. To detect an external magnetic interference field, which can corrupt the sensor signals from the displacement sensors (48, 56, 64, 72), the signal transmitters (50, 58, 66, 74) have identical axial alignments of their magnetic poles, and the signal receivers (52, 60, 68, 76) are in a common plane (80) that is horizontal in their installation position.

Abstract: A compressor system for generating compressed air for a compressed air supply system in a vehicle. The compressor system includes a brushed direct current electric motor (BDC electric motor); a compressor configured to be driven by the BDC electric motor; and a control unit for controlling the BDC electric motor and allocated to the BDC electric motor so as to delimit an operating current of the electric motor. A free-running current path is allocated to the control unit, the free-running current path being configured to delimit the operating current of the electric motor in a variable manner. A switch controller is allocated to the control unit, the switch controller being configured to specify a switched-on time period (t_ON) and/or a switched-off time period (t_OFF) for the electric motor in a variable manner.

Abstract: A compressor for producing compressed air, in particular for a compressed air supply system of a vehicle, includes an electric motor in the form of a brushed direct current electric motor. The compressor has at least one first and one second compressor step, which can be driven by the electric motor. The motor can be controlled by means of an electronic control module of a control device by limiting an operational flow of the motor.

Abstract: A compressor system for generating compressed air for a compressed air supply system in a vehicle. The compressor system includes a brushed direct current electric motor (BDC electric motor); a compressor configured to be driven by the BDC electric motor; and a control unit for controlling the BDC electric motor and allocated to the BDC electric motor so as to delimit an operating current of the electric motor. A free-running current path is allocated to the control unit, the free-running current path being configured to delimit the operating current of the electric motor in a variable manner. A switch controller is allocated to the control unit, the switch controller being configured to specify a switched-on time period (t_ON) and/or a switched-off time period (t_OFF) for the electric motor in a variable manner.

Abstract: A compressor for producing compressed air, in particular for a compressed air supply system of a vehicle, includes an electric motor in the form of a brushed direct current electric motor. The compressor has at least one first and one second compressor step, which can be driven by the electric motor. The motor can be controlled by means of an electronic control module of a control device by limiting an operational flow of the motor.

Abstract: A measurement method for a mechatronics apparatus, which includes an electromagnetically actuated component, an electronic control circuit, and at least one sensor, is selectively timed to minimize electromagnetic interference between the electromagnetically actuated component and the sensor(s). This is accomplished by restricting a sensor measurement to a time window, during which time the electromagnetically actuated component either has no current flow, or has a current change magnitude that is lower than a predetermined limit.

Abstract: A level control system controls the distance between the vehicle axles and the vehicle frame of a vehicle. The suspension is a full or partial air suspension, wherein the vehicle frame over the vehicle axles is supported via air suspension bellows. A vehicle inclination, i.e. a non-parallel alignment between vehicle frame and one or more of vehicle axles may occur as a result of various situations which may be dramatically different from one another. Uneven support of the vehicle represents one cause of vehicle inclination, for example, when one wheel of a vehicle axle is standing on the sidewalk. In order to avoid air losses, a vehicle level is not compensated for while the vehicle is stopped. Instead, the existing inclination is maintained and is entered into the control system as a target level. All level changes which occur due to changes in the load of the vehicle are compensated for by means of this prescribed target value.