Abstract: A system for facilitating automated handling using laser ablation system is described that includes a sample generation system. In an embodiment, the sample generation system can include a sample chamber with a sample chamber body, a transmission window and a sealing member coupled to the sample chamber body, an inlet conduit extending through the sample chamber body and intersecting a sidewall of the interior space, and an outlet conduit extending through the sample chamber body and intersecting at least one of the sidewall of the interior or a lower surface of the sample chamber body; a placement system including a frame, and an actuator assembly coupled to the frame, where the actuator assembly is configured to place the sample adjacent to the sample chamber for laser ablation; and a laser configured to produce a laser beam that is propagated along a beam path to irradiate the sample.

Abstract: A laser-ablation-based analytical system can include a sample chamber input, a make-up gas input, a vacuum pump, and an output flow. The sample chamber input can be configured to deliver a sample chamber gas flow comprised of combination of a laser-ablated sample and a sample-carrier gas from a sample chamber. The make-up gas input can be configured to provide an amount of make-up gas to supplement the combination of the laser-ablated sample and the sample-carrier gas. The vacuum pump can be fluidly connected to the sample chamber input and the make-up gas input, the vacuum pump configured to create a negative pressure in a sample transport gas downstream of the vacuum pump, the sample transport gas including the make-up gas, the laser-ablated sample, and the sample-carrier gas. The output flow can be configured to deliver the sample transport gas from the vacuum pump to a detection device.

Abstract: A system for facilitating automated handling using laser ablation system is described that includes a sample generation system. In an embodiment, the sample generation system can include a sample chamber with a sample chamber body, a transmission window and a sealing member coupled to the sample chamber body, an inlet conduit extending through the sample chamber body and intersecting a sidewall of the interior space, and an outlet conduit extending through the sample chamber body and intersecting at least one of the sidewall of the interior or a lower surface of the sample chamber body; a placement system including a frame, and an actuator assembly coupled to the frame, where the actuator assembly is configured to place the sample adjacent to the sample chamber for laser ablation; and a laser configured to produce a laser beam that is propagated along a beam path to irradiate the sample.

Abstract: A laser-ablation-based analytical system can include a sample chamber input, a make-up gas input, a vacuum pump, and an output flow. The sample chamber input can be configured to deliver a sample chamber gas flow comprised of combination of a laser-ablated sample and a sample-carrier gas from a sample chamber. The make-up gas input can be configured to provide an amount of make-up gas to supplement the combination of the laser-ablated sample and the sample-carrier gas. The vacuum pump can be fluidly connected to the sample chamber input and the make-up gas input, the vacuum pump configured to create a negative pressure in a sample transport gas downstream of the vacuum pump, the sample transport gas including the make-up gas, the laser-ablated sample, and the sample-carrier gas. The output flow can be configured to deliver the sample transport gas from the vacuum pump to a detection device.