Patents by Inventor Robert Webster
Robert Webster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240183822Abstract: Devices that include a low sensitivity bulk acoustic wave (BAW) resonator sensor including a surface to which a low recognition component is immobilized, the low recognition component being configured to selectively bind the analyte, an analyte molecule to which a tag is linked, or a tag, or any one of these molecules to which an amplification element-linked second recognition component is bound; a high sensitivity BAW resonator sensor including a surface to which a high recognition component is immobilized, the high recognition component being configured to selectively bind the analyte, an analyte molecule to which a tag is linked, or a tag, or any one of these molecules to which an amplification element-linked second recognition component is bound; one or more containers housing an amplification molecule, the amplification element-linked second recognition component, and optionally one or both of the tag and the analyte molecule.Type: ApplicationFiled: January 2, 2024Publication date: June 6, 2024Inventors: James Russell Webster, Ian Robert Harmon
-
Publication number: 20240173302Abstract: A pharmaceutical composition comprising at least one endothelin A receptor inhibitor or a pharmaceutically acceptable salt thereof and at least one chemokine receptor 2 (CCR2) inhibitor or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: March 18, 2022Publication date: May 30, 2024Inventors: Robert Pearson Shepherd, Nina Webster
-
Publication number: 20240152320Abstract: A hub is configured to provide voice control without assistance from a remote system, which allows the hub to provide a user with the ability to control second devices in an environment by issuing voice commands, even when the hub is unable to communicate with the remote system over a wide area network (e.g., the Internet). The hub is also configured to execute rules without assistance from the remote system, which allows the hub to execute rules, even when the hub is unable to communicate with the remote system over a wide area network (e.g., the Internet).Type: ApplicationFiled: November 20, 2023Publication date: May 9, 2024Inventors: Mark Aran Aiken, Stanislaw Ignacy Pasko, Olusanya Temitope Soyannwo, Vibhav Hemant Salgaonkar, Adam Barry Fineberg, Roger Robert Webster, Makarand Damle, Rohan Mutagi, Philip Alexander Lee
-
Publication number: 20240138865Abstract: The present disclosure provides for an endoscopic apparatus and methods. The apparatus may include a steerable sheath, a control wire disposed within the steerable sheath, and a basket disposed on the control wire. The steerable sheath may be actuated to form a bend, advancing movements of the control wire may cause the basket to project out of the steerable sheath and expand, and retreating movements of the control wire may cause the basket to retract into the steerable sheath and contract.Type: ApplicationFiled: August 25, 2023Publication date: May 2, 2024Applicant: EndoTheia, Inc.Inventors: Joshua Gafford, Scott Webster, Patrick Anderson, Caleb Rucker, Robert Webster
-
Publication number: 20240138659Abstract: The present disclosure provides an endoscopic apparatus and associated methods. The apparatus may include a steerable tool having a first flexible tube concentrically nested within a second flexible tube. The apparatus may include an end cap disposed on the steerable tool, an image sensor disposed on the end cap, and one or more light sources disposed on the end cap. The apparatus may be configured for accessing a region within a middle ear cavity of a patient. As such, the apparatus may further include a flexible tube, through which the steerable tool may extend, as well as a pre-curved rigid tube, through which the flexible tube may extend, thus allowing the apparatus to be deployed for middle ear access.Type: ApplicationFiled: August 25, 2023Publication date: May 2, 2024Applicant: EndoTheia, Inc.Inventors: Joshua Gafford, Jake Childs, Laura Davis, Caleb Rucker, Patrick Anderson, Scott Webster, Robert Webster
-
Patent number: 11969443Abstract: Self-driving surface antigen-regulated promoter-therapeutic payload constructs containing antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the surface antigen-regulated promoter-therapeutic payload constructs are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making self-driving surface antigen-regulated promoter-therapeutic payload constructs in T-cells are also disclosed.Type: GrantFiled: March 6, 2020Date of Patent: April 30, 2024Assignee: LENTIGEN TECHNOLOGY, INC.Inventors: Dina Schneider, Boro Dropulic, Brian Robert Webster
-
Patent number: 11927111Abstract: A blade for a turbine engine with a wall separating a cooling fluid flow and a hot gas fluid flow and having a heated surface along which the hot gas fluid flow flows and a cooled surface facing the cooling fluid flow. A plurality of cooling holes each having a passage extending between an inlet at the cooled surface and an outlet at the heated surface. The outlet extending between an upstream end and a downstream end with respect to the hot gas fluid flow to define a distance, the passage defining a centerline forming a first angle (?) with the heated surface.Type: GrantFiled: June 9, 2022Date of Patent: March 12, 2024Assignee: General Electric CompanyInventors: Jonathan Michael Rausch, Zachary Daniel Webster, Kevin Robert Feldmann, Andrew David Perry, Kirk Douglas Gallier, Daniel Endecott Osgood
-
Patent number: 11822857Abstract: A hub is configured to provide voice control without assistance from a remote system, which allows the hub to provide a user with the ability to control second devices in an environment by issuing voice commands, even when the hub is unable to communicate with the remote system over a wide area network (e.g., the Internet). The hub is also configured to execute rules without assistance from the remote system, which allows the hub to execute rules, even when the hub is unable to communicate with the remote system over a wide area network (e.g., the Internet).Type: GrantFiled: July 9, 2020Date of Patent: November 21, 2023Assignee: Amazon Technologies, Inc.Inventors: Mark Aran Aiken, Stanislaw Ignacy Pasko, Olusanya Temitope Soyannwo, Vibhav Hemant Salgaonkar, Adam Barry Fineberg, Roger Robert Webster, Makarand Damle, Rohan Mutagi, Philip Alexander Lee
-
Patent number: 11815142Abstract: This disclosure relates to a magnetorheological (MR) brake. The MR brake includes a rotor constructed at least partially of a ferromagnetic material, and a housing that supports the rotor such that the rotor and the housing are rotatable relative to each other about an axis, wherein the housing and rotor are configured such that a fluid gap is defined between the housing and the rotor, and wherein portions of the housing adjacent the rotor are constructed at least partially of a ferromagnetic material. An MR fluid is disposed in the fluid gap. A current-carrying coil is excitable to generate a magnetic field within ferromagnetic portions of the rotor and the housing and acts on the MR fluid. At least one element constructed of a material having low magnetic permeability is configured route the lines of magnetic flux through surrounding higher permeability material on opposite sides of the fluid gap.Type: GrantFiled: February 3, 2020Date of Patent: November 14, 2023Assignee: VANDERBILT UNIVERSITYInventors: Patrick Wellborn, Jason Mitchell, Robert Webster, III
-
Publication number: 20230134917Abstract: A surgical system, method, and apparatus for suturing a first anatomical structure to a second anatomical structure of a subject includes an endoscope tube for being advanced through a lumen of the first anatomical structure to a surgical site near the second anatomical structure. A manipulator arm extends through the endoscope tube to the surgical site, and includes a first concentric tube manipulator with an end effector configured to grasp and manipulate a suture at the surgical site. A needle arm extends through the endoscope tube to the surgical site, and includes a second concentric tube manipulator with a needle tip configured to pierce the tissue of the first and second anatomical structures. The needle arm is also configured to grasp the suture and to retract and pull the suture through the pierced tissue so that the suture extends through and forms stitching that stitches together the first and second anatomical structures.Type: ApplicationFiled: March 9, 2021Publication date: May 4, 2023Inventors: Ernar AMANOV, Dominick ROPELLA, Naren NIMMAGADDA, Nicholas KAVOUSSI, Neal DILLON, Richard HENDRICK, Stanley HERRELL, Robert WEBSTER
-
Publication number: 20230120303Abstract: Movement of an autonomously motile device may be controlled by a user device. The user device may display image data captured by a camera of the autonomously motile device; a user may provide input, such as a touch gesture on a display screen, indicating a command for the autonomously motile device to move to a location indicated by the input. The autonomously motile device determines a coordinate of the input and a time of the touch input; the autonomously motile device then determines a direction and distance of a corresponding movement.Type: ApplicationFiled: July 28, 2022Publication date: April 20, 2023Inventors: Amy Solenberg, Anil Kumar Katta, Swati S. Rao, Swetha Bijoy, Anthony George Robson, David Allen Fotland, Robert Franklin Ebert, Roger Robert Webster, Adam Fineberg
-
Publication number: 20230033294Abstract: The present invention provides a novel isolated succinate prodrug as the free compound or a salt, hydrate, solvate or complex thereof being cell permeable and aimed for increasing the ATP-production in mitochondria. The compound is useful in the medical treatment of a range of diseases, in nutritional supplements, nutricosmetics and in cosmetics.Type: ApplicationFiled: September 14, 2022Publication date: February 2, 2023Inventors: Magnus Joakim HANSSON, Alvar GRÖNBERG, Mats Eskil ELMÉR, Mark Richard FARMERY, Lee Robert WEBSTER, Steven James MOSS, Matthew Alan GREGORY
-
Patent number: 11565998Abstract: The present invention provides a novel isolated succinate prodrug as the free com-pound or a salt, hydrate, solvate or complex thereof being cell permeable and aimed for increasing the ATP-production in mitochondria. The compound is useful in the medical treatment of a range of diseases, in nutritional supplements, nutricosmetics and in cosmetics.Type: GrantFiled: June 18, 2020Date of Patent: January 31, 2023Assignee: ABLIVA ABInventors: Magnus Joakim Hansson, Alvar Grönberg, Mats Eskil Elmér, Mark Richard Farmery, Steven James Moss, Lee Robert Webster, Matthew Alan Gregory
-
Patent number: 11524877Abstract: The disclosure provides an apparatus and mechanism for and elevator safety mechanism. The safety mechanism can include a lock bar, a beak assembly, a detector assembly, and a linkage rod providing communication between the beak assembly and the detector assembly. The beak of the beak assembly can engage a catch in the lock bar when the safety mechanism is in a closed position, preventing the doors of the elevator from further opening.Type: GrantFiled: December 14, 2020Date of Patent: December 13, 2022Inventor: Robert Webster
-
Patent number: 11520332Abstract: An autonomous mobile device (AMD) uses sensors to explore a physical space and determine the locations of obstacles. Simultaneous localization and mapping (SLAM) techniques are used by the AMD to designate as keyframes some images and their associated descriptors of features in the space. Each keyframe indicates a location and orientation of the AMD relative to those features. Anchors are specified relative to keyframes. A marker is specified relative to one or more anchors. Because markers are associated with features in the physical space, they maintain their association with the physical space through various processes such as SLAM loop closures. Markers may specify locations in the physical space, such as navigation waypoints, navigation destinations such as a goal pose for exploring an unexplored area, as an observation target to facilitate exploration, and so forth. Markers may also be used to specify block listed locations to be avoided during exploration.Type: GrantFiled: December 3, 2019Date of Patent: December 6, 2022Assignee: AMAZON TECHNOLOGIES, INC.Inventors: James Charles Zamiska, David Allen Fotland, Roger Robert Webster, Mohit Deshpande, Robert Franklin Ebert, Nikhil Sharma, Rachel Liao, Chang Young Kim
-
Patent number: 11429110Abstract: An autonomous mobile device (AMD) moves through a physical space without human intervention. Data from sensors on the AMD are used to determine an occupancy map indicative of obstacles and their locations in the physical space. A navigation map is created from the occupancy map by inflating the apparent size of the obstacles indicated by the occupancy map. In one implementation the inflation process dynamically skips some portions of the occupancy map based on the presence of an obstacle and a designated inflation distance. The extent of the inflation is based on a size of the AMD. The navigation map is then used for path planning.Type: GrantFiled: May 24, 2019Date of Patent: August 30, 2022Assignee: AMAZON TECHNOLOGIES, INC.Inventors: Roger Robert Webster, Rajasimman Madhivanan, Madan Jayaprakasam
-
Patent number: 11422565Abstract: A robot comprises a plurality of sensors on a mobile chassis and may move about an environment in which people may be expected to follow particular cultural conventions. Movement of the robot may be constrained to honor these cultural conventions that are appropriate for the people in the environment. For example, when the robot is used within the United States, the robot tends to move along the right-hand side of a hallway. In comparison, when the robot is used within Japan the robot tends to move along the left-hand side of the hallway. The cultural conventions may be implemented as one-way gates present at specified locations in an occupancy map of the environment. The gates have no physical presence in the environment, but have the effect of placing a constraint on where the robot is permitted to move.Type: GrantFiled: March 16, 2018Date of Patent: August 23, 2022Assignee: AMAZON TECHNOLOGIES, INC.Inventors: Roger Robert Webster, Rajasimman Madhivanan
-
Patent number: 11409279Abstract: Movement of an autonomously motile device may be controlled by a user device. The user device may display image data captured by a camera of the autonomously motile device; a user may provide input, such as a touch gesture on a display screen, indicating a command for the autonomously motile device to move to a location indicated by the input. The autonomously motile device determines a coordinate of the input and a time of the touch input; the autonomously motile device then determines a direction and distance of a corresponding movement.Type: GrantFiled: September 26, 2019Date of Patent: August 9, 2022Assignee: Amazon Technologies, Inc.Inventors: Amy Solenberg, Anil Kumar Katta, Swati S Rao, Swetha Bijoy, Anthony George Robson, David Allen Fotland, Robert Franklin Ebert, Roger Robert Webster, Adam Fineberg
-
Patent number: 11409296Abstract: An autonomous mobile device (AMD) moves through a physical space without human intervention. Data from sensors on the AMD is used to determine an occupancy map indicative of obstacles and their locations in the physical space. Obstacles may be static, variable, or dynamic. For example, walls are static, doors which open and close are variable, and people moving through the environment are dynamic. Regions in the occupancy map that the AMD has visited but which are shown by the occupancy map as containing obstacles are identified as being variable regions. To determine possible paths through the physical space during autonomous movement, the variable regions are considered to be unoccupied by obstacles and traversable. Information about how often the variable region transitions between traversable and impassible states may also be used to determine the possible paths.Type: GrantFiled: September 17, 2019Date of Patent: August 9, 2022Assignee: AMAZON TECHNOLOGIES, INC.Inventors: Chang Young Kim, Roger Robert Webster
-
Publication number: 20220168344Abstract: Self-driving surface antigen-regulated promoter-therapeutic payload constructs containing antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the surface antigen-regulated promoter-therapeutic payload constructs are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making self-driving surface antigen-regulated promoter-therapeutic payload constructs in T-cells are also disclosed.Type: ApplicationFiled: March 6, 2020Publication date: June 2, 2022Inventors: Dina Schneider, Boro Dropulic, Brian Robert Webster