Patents by Inventor Robert William Scott

Robert William Scott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLID FORMS OF AN ANTIVIRAL COMPOUND
    Publication number: 20150141659
    Abstract: Amorphous and crystalline solid forms of the anti-HCV compound (1-{3-[6-(9,9-difluoro-7-{2-[5-(2-methoxycarbonylamino-3-methyl-butyryl)-5-aza-spiro[2.4]hept-6-yl]-3H-imidazol-4-yl}-9H-fluoren-2-yl)-1H-benzoimidazol-2-yl]-2-aza-bicyclo[2.2.1]heptane-2-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the amorphous and crystalline forms.
    Type: Application
    Filed: January 20, 2015
    Publication date: May 21, 2015
    Inventors: Erik Mogalian, Robert William Scott, Bing Shi, Fang Wang
  • Methods for preparing anti-viral nucleotide analogs
    Patent number: 9029534
    Abstract: Methods for isolating 9-{(R)-2-[((S)—{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing, in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)—{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: May 12, 2015
    Assignee: Gilead Sciences, Inc.
    Inventors: Denise A. Colby, Andrew Anthony Martins, Benjamin James Roberts, Robert William Scott, Nicole S. White
  • Solid forms of an antiviral compound
    Patent number: 8969588
    Abstract: Amorphous and crystalline solid forms of the anti-HCV compound (1-{3-[6-(9,9-difluoro-7-{2 -[5-(2-methoxycarbonylamino-3-methyl-butyryl)-5-aza-spiro[2.4]hept-6-yl]-3H-imidazol-4-yl}-9H-fluoren-2-yl)-1H-benzoimidazol-2-yl]-2-aza-bicyclo[2.2.1]heptane-2-carbonyl}-2-methyl -propyl)-carbamic acid methyl ester (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the amorphous and crystalline forms.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: March 3, 2015
    Assignee: Gilead Pharmasset LLC
    Inventors: Robert William Scott, Fang Wang, Bing Shi, Erik Mogalian
  • METHODS FOR PREPARING ANTI-VIRAL NUCLEOTIDE ANALOGS
    Publication number: 20140128602
    Abstract: Methods for isolating 9-{(R)-2-[((S)—{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing, in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)—{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
    Type: Application
    Filed: January 14, 2014
    Publication date: May 8, 2014
    Applicant: GILEAD SCIENCES, INC.
    Inventors: Denise A. Colby, Andrew Anthony Martins, Benjamin James Roberts, Robert William Scott, Nicole S. White
  • Methods for preparing anti-viral nucleotide analogs
    Patent number: 8664386
    Abstract: Methods for isolating 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing, in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
    Type: Grant
    Filed: October 3, 2012
    Date of Patent: March 4, 2014
    Assignee: Gilead Sciences, Inc.
    Inventors: Denise A. Colby, Andrew Anthony Martins, Benjamin James Roberts, Robert William Scott, Nicole S. White
  • SYNTHESIS OF ANTIVIRAL COMPOUND
    Publication number: 20130324740
    Abstract: The present disclosure provides processes for the preparation of a compound of formula I: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates to compounds of formula I.
    Type: Application
    Filed: March 13, 2013
    Publication date: December 5, 2013
    Applicant: Gilead Sciences, Inc.
    Inventors: Robert William Scott, Justin Philip Vitale, Kenneth Stanley Matthews, Martin Gerald Teresk, Alexandra Formella, Jared Wayne Evans
  • SOLID FORMS OF AN ANTIVIRAL COMPOUND
    Publication number: 20130324496
    Abstract: Amorphous and crystalline solid forms of the anti-HCV compound (1-{3-[6-(9,9-difluoro-7-{2-[5-(2-methoxycarbonylamino-3-methyl-butyryl)-5-aza-spiro[2.4]hept-6-yl]-3H-imidazol-4-yl}-9H-fluoren-2-yl)-1H-benzoimidazol-2-yl]-2-aza-bicyclo[2.2.1]heptane-2-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the amorphous and crystalline forms.
    Type: Application
    Filed: March 13, 2013
    Publication date: December 5, 2013
    Inventors: Robert William Scott, Fang Wang, Bing Shi, Erik Mogalian
  • Methods for preparing anti-viral nucleotide analogs
    Publication number: 20130090473
    Abstract: Methods for isolating 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing, in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
    Type: Application
    Filed: October 3, 2012
    Publication date: April 11, 2013
    Inventors: Denise A. Colby, Andrew Anthony Martins, Benjamin James Roberts, Robert William Scott, Nicole S. Solomon
  • Methods for the Preparation of HCV Polymerase Inhibitors
    Publication number: 20110070187
    Abstract: The present invention relates to methods and compounds useful in the preparation of compounds of the formula (I).
    Type: Application
    Filed: August 17, 2010
    Publication date: March 24, 2011
    Inventors: Christopher Frederick Matthews, Robert William Scott, John Lloyd Tucker
  • Methods for the preparation of HCV polymerase inhibitors
    Patent number: 7807838
    Abstract: The present invention relates to methods and compounds useful in the preparation of compounds of the formula (I).
    Type: Grant
    Filed: August 16, 2006
    Date of Patent: October 5, 2010
    Assignee: Pfizer Inc.
    Inventors: Christopher Frederick Matthews, Robert William Scott, John Lloyd Tucker
  • METHODS FOR THE PREPARATION OF HCV POLYMERASE INHIBITORS
    Publication number: 20090023921
    Abstract: The present invention relates to methods and compounds useful in the preparation of compounds of the formula (I).
    Type: Application
    Filed: August 16, 2006
    Publication date: January 22, 2009
    Inventors: Christopher Frederick Matthews, Robert William Scott, John Lloyd Tucker
  • HIV protease inhibitors, compositions containing the same, their pharmaceutical uses, material for their synthesis
    Patent number: 7169932
    Abstract: Compounds of the formula: where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.
    Type: Grant
    Filed: December 4, 2003
    Date of Patent: January 30, 2007
    Assignee: Pfizer Inc.
    Inventors: David John Kucera, Robert William Scott
  • HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis
    Patent number: 7094909
    Abstract: The present invention concerns processes for preparing compounds of formula (I-H), or a prodrug, pharmaceutically active metabolite, or pharmaceutically active salt or solvate thereof, which are useful as inhibitors of the HIV protease enzyme.
    Type: Grant
    Filed: December 4, 2003
    Date of Patent: August 22, 2006
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: David John Kucera, Robert William Scott
  • HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis
    Publication number: 20040204591
    Abstract: The present invention concerns processes for preparing compounds of formula (I-H), or a prodrug, pharmaceutically active metabolite, or pharmaceutically active salt or solvate thereof, 1
    Type: Application
    Filed: December 4, 2003
    Publication date: October 14, 2004
    Applicant: Agouron Pharmaceuticals, Inc.
    Inventors: David John Kucera, Robert William Scott
  • HIV protease inhibitors, compositions containing the same, their pharmaceutical uses, material for their synthesis
    Publication number: 20040171842
    Abstract: Compounds of the formula: 1
    Type: Application
    Filed: December 4, 2003
    Publication date: September 2, 2004
    Applicant: Pfizer Inc
    Inventors: David John Kucera, Robert William Scott