Patents by Inventor Roberta DI BENEDETTO

Roberta DI BENEDETTO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL CARRIERS AND CONJUGATION METHODS
    Publication number: 20240000958
    Abstract: The present invention is directed to a polysaccharide conjugate comprising or consisting of a one or more polysaccharide conjugated to a carrier polypeptide, wherein the carrier polypeptide is selected from the group consisting of (a) a Streptococcus pyogenes SpyAD (Spy0269, GAS40), a Streptococcus pyogenes SpyCEP (Spy0416, GAS57), or Streptococcus pyogenes SLO (Spy0167, GAS25); (b) CRM197; or (c) a variant, fragment and/or fusion of (a) or (b), improved conjugation methods, and uses of said conjugates for preventing or treating disease.
    Type: Application
    Filed: November 12, 2021
    Publication date: January 4, 2024
    Inventors: Francesca Micoli, Roberta Di Benedetto, Allan Saul
  • nOMV-ANTIGEN CONJUGATED COMPOUNDS AND USE THEREOF
    Publication number: 20230137914
    Abstract: The provided technology is in the field of conjugating native, non-detergent extracted, outer membrane vesicles (nOMV) to antigens to form nOMV-linker-antigen conjugates, which are particularly useful for immunogenic compositions and immunisation; processes for the preparation and use of such conjugates is also provided.
    Type: Application
    Filed: November 23, 2017
    Publication date: May 4, 2023
    Applicant: GLAXOSMITHKLINE BIOLOGICALS, S.A.
    Inventors: Roberta DI BENEDETTO, Francesca MICOLI, Allan James SAUL
  • MULTI-FUNCTIONALIZED noMV CONJUGATES
    Publication number: 20220008529
    Abstract: The present invention is in the field of conjugating native, non-detergent extracted, outer membrane vesicles (nOMV) to multiple antigens to form multi functionalized nOMV-antigen conjugated derivatives, which are particularly useful for immunogenic compositions and immunisation; processes for the preparation and use of such conjugates are also provided.
    Type: Application
    Filed: August 8, 2018
    Publication date: January 13, 2022
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Renzo ALFINI, Roberta DI BENEDETTO, Francesca MICOLI, Allan James SAUL