Patents by Inventor Robin Andrew James Smith

Robin Andrew James Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carbon monoxide releasing norbornenone compounds
    Patent number: 11072584
    Abstract: The present invention provides organic compounds which are capable of releasing carbon monoxide under physiological conditions or pH trigger, and to the use of such compounds for conditioning a cell, tissue or organ, for example, to protect against ischaemic injury during a transplant event.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: July 27, 2021
    Assignee: Otago Innovation Limited
    Inventors: Ivan Andrew Sammut, Joanne Clare Harrison, Russell James Hewitt, Morgayn Iona Read, Nathan John Stanley, Laura Molly Woods, Jui Thiang Brian Kueh, Morgan Jay-Smith, Robin Andrew James Smith, Gregory Giles, Lesley Larsen, David Rennison, Margaret Anne Brimble, David Samuel Larsen
  • CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS
    Publication number: 20200109115
    Abstract: The present invention provides organic compounds which are capable of releasing carbon monoxide under physiological conditions or pH trigger, and to the use of such compounds for conditioning a cell, tissue or organ, for example, to protect against ischaemic injury during a transplant event.
    Type: Application
    Filed: December 3, 2019
    Publication date: April 9, 2020
    Inventors: Ivan Andrew SAMMUT, Joanne Clare HARRISON, Russell James HEWITT, Morgayn Iona READ, Nathan John STANLEY, Laura Molly WOODS, Jui Thiang Brian KUEH, Morgan JAY-SMITH, Robin Andrew James SMITH, Gregory GILES, Lesley LARSEN, David RENNISON, Margaret Anne BRIMBLE, David Samuel LARSEN
  • Carbon monoxide releasing norbornenone compounds
    Patent number: 10494344
    Abstract: The present invention provides organic compounds which are capable of releasing carbon monoxide under physiological conditions or pH trigger, and to the use of such compounds for conditioning a cell, tissue or organ, for example, to protect against ischaemic injury during a transplant event.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: December 3, 2019
    Assignee: Otago Innovation Limited
    Inventors: Ivan Andrew Sammut, Joanne Clare Harrison, Russell James Hewitt, Morgayn Iona Read, Nathan John Stanley, Laura Molly Woods, Jui Thiang Brian Kueh, Morgan Jay-Smith, Robin Andrew James Smith, Gregory Giles, Lesley Larsen, David Rennison, Margaret Anne Brimble, David Samuel Larsen
  • CARBON MONOXIDE RELEASING NORBORNENONE COMPOUNDS
    Publication number: 20180346420
    Abstract: The present invention provides organic compounds which are capable of releasing carbon monoxide under physiological conditions or pH trigger, and to the use of such compounds for conditioning a cell, tissue or organ, for example, to protect against ischaemic injury during a transplant event.
    Type: Application
    Filed: November 30, 2016
    Publication date: December 6, 2018
    Inventors: Ivan Andrew SAMMUT, Joanne Clare HARRISON, Russell James HEWITT, Morgayn Iona READ, Nathan John STANLEY, Laura Molly WOODS, Jui Thiang Brian KUEH, Morgan JAY-SMITH, Robin Andrew James SMITH, Gregory GILES, Lesley LARSEN, David RENNISON, Margaret Anne BRIMBLE, David Samuel LARSEN
  • Mitochondria-targeted dicarbonyl sequestering compounds
    Patent number: 9963474
    Abstract: The invention relates to compounds having Formula (1): A-L-B or pharmaceutically acceptable salts thereof, wherein: A is a dicarbonyl sequestering moiety comprising a substituted aryl group or a substituted heteroaryl group; L is an optional linker moiety; and B is a mitochondrial targeting moiety. The invention also relates to pharmaceutical compositions containing such compounds and salts, and to the use of such compounds and salts for treating diabetes, preferably hyperglycemic diabetes. A mass spectrometry probe and to a method of labelling a biological molecule 1 for mass spectrometry detection are also described.
    Type: Grant
    Filed: November 21, 2014
    Date of Patent: May 8, 2018
    Assignee: Medical Research Council
    Inventors: Michael Patrick Murphy, Robin Andrew James Smith, Richard Charles Hartley
  • Nitric Oxide Donors
    Publication number: 20170182170
    Abstract: The invention relates to novel NO donors which are targeted to the mitochondria. The NO donor compounds of the invention allow NO to be selectively provided to the mitochondria.
    Type: Application
    Filed: March 10, 2017
    Publication date: June 29, 2017
    Inventors: Robin Andrew James SMITH, Michael Patrick MURPHY
  • Nitric oxide donors
    Patent number: 9629859
    Abstract: The invention relates to novel NO donors which are targeted to the mitochondria. The NO donor compounds of the invention allow NO to be selectively provided to the mitochondria.
    Type: Grant
    Filed: May 19, 2015
    Date of Patent: April 25, 2017
    Assignee: Medical Research Council
    Inventors: Robin Andrew James Smith, Michael Patrick Murphy
  • MITOCHONDRIA-TARGETED DICARBONYL SEQUESTERING COMPOUNDS
    Publication number: 20160289252
    Abstract: The invention relates to compounds having Formula (1): A-L-B or pharmaceutically acceptable salts thereof, wherein: A is a dicarbonyl sequestering moiety comprising a substituted aryl group or a substituted heteroaryl group; L is an optional linker moiety; and B is a mitochondrial targeting moiety. The invention also relates to pharmaceutical compositions containing such compounds and salts, and to the use of such compounds and salts for treating diabetes, preferably hyperglycemic diabetes. A mass spectrometry probe and to a method of labelling a biological molecule 1 for mass spectrometry detection are also described.
    Type: Application
    Filed: November 21, 2014
    Publication date: October 6, 2016
    Inventors: Michael Patrick MURPHY, Robin Andrew James SMITH, Richard Charles HARTLEY
  • Nitric Oxide Donors
    Publication number: 20150250804
    Abstract: The invention relates to novel NO donors which are targeted to the mitochondria. The NO donor compounds of the invention allow NO to be selectively provided to the mitochondria.
    Type: Application
    Filed: May 19, 2015
    Publication date: September 10, 2015
    Inventors: Robin Andrew James Smith, Michael Patrick Murphy
  • Nitric oxide donors
    Patent number: 9045505
    Abstract: The invention relates to novel NO donors which are targeted to the mitochondria. The NO donor compounds of the invention allow NO to be selectively provided to the mitochondria.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: June 2, 2015
    Assignees: University of Otago, Medical Research Council
    Inventors: Robin Andrew James Smith, Michael Patrick Murphy
  • NITRIC OXIDE DONORS
    Publication number: 20100240615
    Abstract: The invention relates to novel NO donors which are targeted to the mitochondria. The NO donor compounds of the invention allow NO to be selectively provided to the mitochondria.
    Type: Application
    Filed: March 26, 2010
    Publication date: September 23, 2010
    Applicants: University of Orago, Medical Research Council
    Inventors: Robin Andrew James Smith, Michael Patrick Murphy
  • NITRIC OXIDE DONORS
    Publication number: 20090233873
    Abstract: The invention relates to novel NO donors which are targeted to the mitochondria. The NO donor compounds of the invention allow NO to be selectively provided to the mitochondria.
    Type: Application
    Filed: March 27, 2009
    Publication date: September 17, 2009
    Applicants: University of Otago, Medical Research Council
    Inventors: Robin Andrew James Smith, Michael Patrick Murphy
  • Synthesis of triphenylphosphonium quinols and quinones
    Patent number: 7179928
    Abstract: The methods of preparing quinols and quinones typified by mitoquinol and mitoquinone where a compound typified by idebenone is reacted with Ph3PHX and Ph3P, where X is a halogen atom.
    Type: Grant
    Filed: August 12, 2002
    Date of Patent: February 20, 2007
    Assignee: Antipodean Pharmaceuticals, Inc.
    Inventors: Robin Andrew James Smith, Michael Patrick Murphy