Abstract: Dry, stabilized pharmaceutical spheres comprising a precisely measured amount of the pharmaceutical and a filler material that facilitates the immediate dissolution of the pharmaceutical upon contact with a solution are provided as well as methods for preparing same.

Abstract: A drug dispenser for administering a drug solution ophthalmically. The dispenser comprises a cylindrical member having an open proximal end, a distal end having a hole for dispensing the drug solution, and a connecting passage formed in a sidewall thereof. A plunger is receivable in the proximal end of the cylindrical member and the member is axially slidable on the plunger between a non-mix position and a mix position. The dispenser further comprises a piston having a distal end and a proximal end and slidably disposed within the cylindrical member in sealing engagement therewith. The distal end of the piston is located proximally of the passage and forms a drug chamber with the distal end of the member for storing a drug when the member is in its non-mix position. The proximal end of the piston is distally spaced from the plunger to form a diluent chamber therebetween for storing a diluent when the cylindrical member is in its non-mix position.