Abstract: A method of, and apparatus for, aligning an ophthalmic instrument relative to an eye is disclosed, and can include aligning an esthesiometer with a patient's eye. Other aspects of the method and apparatus of the present invention are further described herein.

Abstract: An electrically-switchable flexible contact lens for conforming to an eye of a user is provided. The lens comprises a liquid crystal cell for changing a focal power of the contact lens, and the liquid crystal cell has a cell gap thickness between a first inner surface and a second inner surface, the liquid crystal cell comprising a diffractive optical element for correcting the vision of a user, wherein the diffractive optical element is arranged to maintain the cell gap thickness by providing support at one or more locations within the cell.

Abstract: A deformable membrane assembly comprises an at least partially flexible fluid-filled envelope, one wall of which is formed by an elastic membrane that is held around its edge by a resiliently bendable supporting ring, a fixed support for the envelope and selectively operable means for causing relative movement between the supporting ring and the support for adjusting the pressure of the fluid in the envelope, thereby to cause the membrane to deform. The bending stiffness of the ring varies round the ring such that upon deformation of the membrane the ring bends variably to control the shape of the membrane to a predefined form. The moving means comprise a plurality of ring-engaging members that are arranged to apply a force to the ring at spaced control points.

Abstract: A deformable membrane assembly comprises an at least partially flexible fluid-filled envelope, one wall of which is formed by an elastic membrane that is held around its edge by a resiliently bendable supporting ring, a fixed support for the envelope and selectively operable means for causing relative movement between the supporting ring and the support for adjusting the pressure of the fluid in the envelope, thereby to cause the membrane to deform. The bending stiffness of the ring varies round the ring such that upon deformation of the membrane the ring bends variably to control the shape of the membrane to a predefined form. The moving means comprise a plurality of ring-engaging members that are arranged to apply a force to the ring at spaced control points.

Abstract: An actuation mechanism for simultaneous actuation of first and second variable focal length lenses is disclosed. Each lens comprises a distensible membrane bounding a fluid-filled cavity, the focal length varying with the degree of curvature of the membrane as it distends. The actuation mechanism comprises a hydraulic master actuator in fluid communication with a hydraulic slave actuator associated with the first lens and with a hydraulic slave actuator associated with the second lens. Each slave actuator is configured to vary the degree of distension of the membrane of its associated lens in response to operation of the master actuator, whereby the master actuator is operable to cause a variation of the degree of distension of the membranes of both the first and second lenses simultaneously.

Abstract: A deformable membrane assembly comprises an at least partially flexible fluid-filled envelope, one wall of which is formed by an elastic membrane that is held around its edge by a resiliently bendable supporting ring, a fixed support for the envelope and selectively operable means for causing relative movement between the supporting ring and the support for adjusting the pressure of the fluid in the envelope, thereby to cause the membrane to deform. The bending stiffness of the ring varies round the ring such that upon deformation of the membrane the ring bends variably to control the shape of the membrane to a predefined form. The moving means comprise a plurality of ring-engaging members that we arranged to apply a force to the ring at spaced control points.

Abstract: An actuation mechanism for simultaneous actuation of first and second variable focal length lenses is disclosed. Each lens comprises a distensible membrane bounding a fluid-filled cavity, the focal length varying with the degree of curvature of the membrane as it distends. The actuation mechanism comprises a hydraulic master actuator in fluid communication with a hydraulic slave actuator associated with the first lens and with a hydraulic slave actuator associated with the second lens. Each slave actuator is configured to vary the degree of distension of the membrane of its associated lens in response to operation of the master actuator, whereby the master actuator is operable to cause a variation of the degree of distension of the membranes of both the first and second lenses simultaneously.

Abstract: An actuation mechanism for simultaneous actuation of first and second variable focal length lenses is disclosed. Each lens comprises a distensible membrane bounding a fluid-filled cavity, the focal length varying with the degree of curvature of the membrane as it distends. The actuation mechanism comprises a hydraulic master actuator in fluid communication with a hydraulic slave actuator associated with the first lens and with a hydraulic slave actuator associated with the second lens. Each slave actuator is configured to vary the degree of distension of the membrane of its associated lens in response to operation of the master actuator, whereby the master actuator is operable to cause a variation of the degree of distension of the membranes of both the first and second lenses simultaneously.

Abstract: The present invention provides a deformable membrane assembly 1 comprising an elastic membrane 8 that is held under tension around its edge by a bendable membrane supporting member 2,10, a body of fluid in contact with one face of the membrane, the pressure of the fluid being controllable for adjusting the shape of the membrane, and one or more bending controllers 24 acting on the supporting member 2, 10 to control the bending of the supporting member in response to loading through tension in the membrane. The bending stiffness of the membrane-supporting member 2, 10 varies round its extent to control the profile of the edge of the membrane 8; etc. upon actuation. A variety of different types of bending controllers are disclosed which permit out-of-plane bending of the supporting member 2, 10 but prevent or control in-plane bending or deformation of the supporting member.

Abstract: A deformable membrane assembly comprises an at least partially flexible fluid-filled envelope, one wall of which is formed by an elastic membrane that is held around its edge by a resiliently bendable supporting ring, a fixed support for the envelope and selectively operable means for causing relative movement between the supporting ring and the support for adjusting the pressure of the fluid in the envelope, thereby to cause the membrane to deform. The bending stiffness of the ring varies round the ring such that upon deformation of the membrane the ring bends variably to control the shape of the membrane to a predefined form. The moving means comprise a plurality of ring-engaging members that are arranged to apply a force to the ring at spaced control points.

Abstract: A deformable membrane assembly comprises an at least partially flexible fluid-filled envelope, one wall of which is formed by an elastic membrane that is held around its edge by a resiliently bendable supporting ring, a fixed support for the envelope and selectively operable means for causing relative movement between the supporting ring and the support for adjusting the pressure of the fluid in the envelope, thereby to cause the membrane to deform. The bending stiffness of the ring varies round the ring such that upon deformation of the membrane the ring bends variably to control the shape of the membrane to a predefined form. The moving means comprise a plurality of ring-engaging members that are arranged to apply a force to the ring at spaced control points.

Abstract: A deformable membrane assembly comprising a fluid-filled envelope, one wall of which is formed by an elastic membrane that is held around its edge by a bendable supporting ring, a support for the envelope and at least three ring-engaging members that are arranged to apply a force to the ring at spaced control points for adjusting the shape of the membrane, with the ring bending to control the shape of the membrane to a predefined form. A control point is provided at or proximate each point on the ring where the profile of the ring that is needed to produce the predefined form of the membrane exhibits a turning point in the direction of the force applied at the control point between two adjacent points where the profile of the ring exhibits an inflection point or a turning point in the opposite direction.

Abstract: Described herein is a contact lens which can actively generate oxygen that is directly supplied to the cornea when it is worn by a patient. The contact lens comprises: a lens body composed of a hydrogel material or preferably a silicone hydrogel material; at least one anode for electrolytically generating oxygen from water in contact with the anode; and at least one cathode operatively coupled with the anode to form an electrolytic cell. The anode and the cathode are embedded within the lens body and operatively connected to a power source and to a control element which automatically applies a potential voltage between the anode and the cathode, drives an electrical current through the anode and the cathode to generate oxygen from electrolysis of water, and controls the timing and duration of electrolysis of water in the eye.

Abstract: A deformable membrane assembly comprises an at least partially flexible fluid-filled envelope, one wall of which is formed by an elastic membrane that is held around its edge by a resiliently bendable supporting ring, a fixed support for the envelope and selectively operable means for causing relative movement between the supporting ring and the support for adjusting the pressure of the fluid in the envelope, thereby to cause the membrane to deform. The bending stiffness of the ring varies round the ring such that upon deformation of the membrane the ring bends variably to control the shape of the membrane to a predefined form. The moving means comprise a plurality of ring-engaging members that are arranged to apply a force to the ring at spaced control points.

Abstract: Described herein is a contact lens which can actively generate oxygen that is directly supplied to the cornea when it is worn by a patient. The contact lens comprises: a lens body composed of a hydrogel material or preferably a silicone hydrogel material; at least one anode for electrolytically generating oxygen from water in contact with the anode; and at least one cathode operatively coupled with the anode to form an electrolytic cell. The anode and the cathode are embedded within the lens body and operatively connected to a power source and to a control element which automatically applies a potential voltage between the anode and the cathode, drives an electrical current through the anode and the cathode to generate oxygen from electrolysis of water, and controls the timing and duration of electrolysis of water in the eye.

Abstract: The present invention provides a deformable membrane assembly 1 comprising an elastic membrane 8 that is held under tension around its edge by a bendable membrane supporting member 2,10, a body of fluid in contact with one face of the membrane, the pressure of the fluid being controllable for adjusting the shape of the membrane, and one or more bending controllers 24 acting on the supporting member 2, 10 to control the bending of the supporting member in response to loading through tension in the membrane. The bending stiffness of the membrane-supporting member 2, 10 varies round its extent to control the profile of the edge of the membrane 8; etc. upon actuation. A variety of different types of bending controllers are disclosed which permit out-of-plane bending of the supporting member 2, 10 but prevent or control in-plane bending or deformation of the supporting member.

Abstract: Test kits for assessing male fertility include a sample holder containing at least one sample chamber, a laser light source, and a light detector to detect scattered light intensity from the sample chamber. The sample holder may include multiple sample chambers connected by sperm swim channels. The test kit may have a housing with a maximum linear dimension of no more than 100 mm. Processing circuitry may be provided that is configured to produce a sperm count and/or sperm motility measurements by processing data from scattered light intensity measurements.