Patents by Inventor Roger Canales

Roger Canales has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230335297
    Abstract: The present embodiments relate to pathogen clearance. Subject matter of the present embodiments are computer-implemented methods, computer systems and computer-readable storage media for predicting the performance of pathogen clearance processes.
    Type: Application
    Filed: August 23, 2021
    Publication date: October 19, 2023
    Inventors: Shyam PANJWANI, Konstantinos SPETSIERIS, Michal MLECZKO, Wensheng WANG, June Zou, Mohammad ANWARUZZAMAN, Oliver HESSE, Roger CANALES, JIARONG CUI, Shengjiang LIU
  • Patent number: 10982218
    Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: April 20, 2021
    Assignee: Mendel Biotechnology, Inc.
    Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
  • Patent number: 10597667
    Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: March 24, 2020
    Assignee: Mendel Biotechnology, Inc.
    Inventors: Peter P. Repetti, T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Katherine Krolikowski, Robert A. Creelman, Frederick D. Hempel, Roderick W. Kumimoto, Luc J. Adam, Neal I. Gutterson, Roger Canales, Emily L. Queen, Jennifer M. Costa
  • Publication number: 20190153457
    Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.
    Type: Application
    Filed: November 20, 2018
    Publication date: May 23, 2019
    Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
  • Patent number: 10167480
    Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.
    Type: Grant
    Filed: November 11, 2013
    Date of Patent: January 1, 2019
    Assignee: Mendel Biotechnology, Inc.
    Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
  • Publication number: 20170121733
    Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.
    Type: Application
    Filed: November 9, 2016
    Publication date: May 4, 2017
    Inventors: Peter P. Repetti, T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Katherine Krolikowski, Robert A. Creelman, Frederick D. Hempel, Roderick W. Kumimoto, Luc J. Adam, Neal I. Gutterson, Roger Canales, Emily L. Queen, Jennifer M. Costa
  • Publication number: 20150166614
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties compared to a reference plant. Sequence information related to these polynucleotides and polypeptides can also be used in bioinformatic search methods and is also disclosed.
    Type: Application
    Filed: August 19, 2014
    Publication date: June 18, 2015
    Inventors: Roderick W. Kumimoto, Luc J. Adam, Roger Canales, Karen S. Century, Robert A. Creelman, Jennifer M. Costa, Neal I. Gutterson, Frederick D. Hempel, Jacqueline E. Heard, Cai-Zhong Jiang, Katherine Krolikowski, Omaira Pineda, Emily L. Kumimoto, Oliver J. Ratcliffe, Peter P. Repetti, T. Lynne Reuber, Jose Luis Riechmann, James Z. Zhang
  • Publication number: 20150135360
    Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.
    Type: Application
    Filed: September 8, 2014
    Publication date: May 14, 2015
    Inventors: Peter P. Repetti, T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Katherine Krolikowski, Robert A. Creelman, Frederick D. Hempel, Roderick W. Kumimoto, Luc J. Adam, Neal I. Gutterson, Roger Canales, Emily L. Queen, Jennifer M. Costa
  • Patent number: 8809630
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties compared to a reference plant. Sequence information related to these polynucleotides and polypeptides can also be used in bioinformatic search methods and is also disclosed.
    Type: Grant
    Filed: November 26, 2007
    Date of Patent: August 19, 2014
    Assignee: Mendel Biotechnology, Inc.
    Inventors: Roderick W. Kumimoto, Luc J. Adam, Roger Canales, Karen S. Century, Robert A. Creelman, Neal I. Gutterson, Frederick D. Hempel, Jacqueline E. Heard, Cai-Zhong Jiang, Katherine Krolikowski, Omaira Pineda, Oliver J. Ratcliffe, Peter P. Repetti, T. Lynne Reuber
  • Publication number: 20140201864
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties compared to a reference plant. Sequence information related to these polynucleotides and polypeptides can also be used in bioinformatic search methods and is also disclosed.
    Type: Application
    Filed: February 11, 2014
    Publication date: July 17, 2014
    Applicant: MENDEL BIOTECHNOLOGY, INC.
    Inventors: Roderick W. Kumimoto, Luc J. Adam, Roger Canales, Karen S. Century, Robert A. Creelman, Jennifer M. Costa, Neal I. Gutterson, Frederick D. Hempel, Jacqueline E. Heard, Cai-Zhong Jiang, Katherine Krolikowski, Omaira Pineda, Emily L. Queen Kumimoto, Oliver J. Ratcliffe, Peter P. Repetti, T. Lynne Reuber, Jose Luis Riechmann, James Z. Zhang
  • Publication number: 20140068821
    Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.
    Type: Application
    Filed: November 11, 2013
    Publication date: March 6, 2014
    Applicant: MENDEL BIOTECHNOLOGY, INC.
    Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
  • Patent number: 8633353
    Abstract: The present invention provides nucleic acid constructs, including plasmids, expression vectors or expression cassettes comprising polynucleotides encoding CCAAT-binding transcription factor polypeptides that have the ability to increase a plant's tolerance to abiotic stress. Polynucleotides encoding functional CCAAT-binding transcription factors were incorporated into expression vectors, introduced into plants, and ectopically expressed. The encoded polypeptides of the invention significantly increased the cold and water deficit tolerance of the transgenic plants, as compared to tolerance to these stresses of control plants.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: January 21, 2014
    Assignee: Mendel Biotechnology, Inc.
    Inventors: Oliver J. Ratcliffe, Jacqueline Heard, Roderick W. Kumimoto, Peter P. Repetti, T. Lynne Reuber, Robert Creelman, Frederick D. Hempel, Neal L. Gutterson, Roger Canales
  • Patent number: 8030546
    Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: October 4, 2011
    Assignee: Mendel Biotechnology, Inc.
    Inventors: T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Neal I. Gutterson, Roger Canales, Emily L. Queen
  • Publication number: 20110126326
    Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.
    Type: Application
    Filed: June 26, 2009
    Publication date: May 26, 2011
    Applicant: MENDEL BIOTECHNOLOGY, INC.
    Inventors: Shiv Tiwari, Roger Canales, T. Lynne Reuber, Karen S. Century, Oliver Ratcliffe
  • Patent number: 7888558
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties, tolerance low nitrogen, cold and water deficit conditions, and resistance to disease, as compared to wild-type or other control plants.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: February 15, 2011
    Assignee: Mendel Biotechnology, Inc.
    Inventors: Neal I. Gutterson, Oliver Ratcliffe, Emily L. Queen, T. Lynne Reuber, Karen S. Century, Roger Canales
  • Publication number: 20090265807
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties compared to a reference plant. Sequence information related to these polynucleotides and polypeptides can also be used in bioinformatic search methods and is also disclosed.
    Type: Application
    Filed: November 26, 2007
    Publication date: October 22, 2009
    Applicant: Mendel Biotechnology, Inc.
    Inventors: Roderick W. Kumimoto, Luc J. Adam, Roger Canales, Karen S. Century, Robert A. Creelman, Jennifer M. Costa, Neal I. Gutterson, Frederick D. Hempel, Jacqueline E. Heard, Cai-Zhong Jiang, Katherine Krolikowski, Omaira Pineda, Emily L. Queen, Oliver J. Ratcliffe, Peter P. Repetti, T. Lynne Reuber, Jose Luis Riechmann, James Z. Zhang
  • Publication number: 20090138981
    Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.
    Type: Application
    Filed: March 17, 2008
    Publication date: May 28, 2009
    Applicant: Mendel Biotechnology, Inc.
    Inventors: Peter P. Repetti, T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Katherine Krolikowski, Robert A. Creelman, Frederick D. Hempel, Roderick W. Kumimoto, Luc J. Adam, Neal I. Gutterson, Roger Canales, Emily L. Queen, Jennifer M. Costa
  • Publication number: 20080163397
    Abstract: The present invention provides nucleic acid constructs, including plasmids, expression vectors or expression cassettes comprising polynucleotides encoding CCAAT-binding transcription factor polypeptides that have the ability to increase a plant's tolerance to abiotic stress. Polynucleotides encoding functional CCAAT-binding transcription factors were incorporated into expression vectors, introduced into plants, and ectopically expressed. The encoded polypeptides of the invention significantly increased the cold and water deficit tolerance of the transgenic plants, as compared to tolerance to these stresses of control plants.
    Type: Application
    Filed: October 30, 2007
    Publication date: July 3, 2008
    Applicant: Mendel Biotechnology, Inc.
    Inventors: Oliver J. Ratcliffe, Jacqueline E. Heard, Roderick W. Kumimoto, Peter P. Repetti, T. Lynne Reuber, Robert A. Creelman, Frederick D. Hempel, Neal I. Gutterson, Roger Canales
  • Publication number: 20070240243
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved abiotic stress tolerance, such as drought stress tolerance, as compared to wild-type or reference plants. Sequence information related to these polynucleotides and polypeptides can also be used in bioinformatic search methods to identify related sequences and is also disclosed.
    Type: Application
    Filed: November 13, 2003
    Publication date: October 11, 2007
    Applicant: Mendel Biotechnology, Inc.
    Inventors: Jacqueline Heard, Jose Riechmann, Robert Creelman, Oliver Ratcliffe, Roger Canales, Peter Repetti, Roderick Kumimoto, Neal Gutterson, T. Reuber, Omaira Pineda, Bradley Sherman
  • Publication number: 20070226839
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties, including resistance to disease and tolerance to low nitrogen, drought, and other abiotic stresses, as compared to wild-type or control plants.
    Type: Application
    Filed: January 29, 2007
    Publication date: September 27, 2007
    Applicant: Mendel Biotechnology
    Inventors: Neal Gutterson, Oliver Ratcliffe, Emily Queen, T. Reuber, Karen Century, Roger Canales