Abstract: The present invention relates generally to the field of pharmaceutical formulations of antibodies. Specifically, the present invention relates to a stable liquid antibody formulation and its pharmaceutical preparation and use. This invention is exemplified by a liquid formulation of a humanised anti-NGF antibody.

Abstract: The disclosure relates to a Vertical Cavity Surface Emitting Laser (100) comprising a first electrical contact (105), a substrate (110), a first Distributed Bragg Reflector (115), an active layer (120), a second Distributed Bragg Reflector (130) and a second electrical contact (135). The Vertical Cavity Surface Emitting Laser comprises at least two current aperture layers (125) arranged below or above the active layer (120), wherein each of the current aperture layers (125) comprises one AlyGa(1-y)As-layer, wherein a first current aperture layer (125a) of the at least two current aperture layers (125) is arranged nearer to the active layer (120) as a second current aperture layer (125b) of the at least two current aperture layers (125), wherein the first current aperture layer (125a) comprises a first current aperture (122a) with a bigger size as a second current aperture (122b) of the second current aperture layer (125b). The disclosure also relates to a method of manufacturing such a VCSEL (100).

Abstract: The present invention relates generally to the field of pharmaceutical formulations of antibodies. Specifically, the present invention relates to a stable liquid antibody formulation and its pharmaceutical preparation and use. This invention is exemplified by a liquid formulation of a humanized anti-NGF antibody.

Abstract: The invention relates to a Vertical Cavity Surface Emitting Laser (100) comprising a first electrical contact (105), a substrate (110), a first Distributed Bragg Reflector (115), an active layer (120), a second Distributed Bragg Reflector (130) and a second electrical contact (135). The Vertical Cavity Surface Emitting Laser comprises at least one AlyGa(1-y)As-layer with 0.95?y?1 with a thickness of at least 40 nm, wherein the AlyGa(1-y )As-layer is separated by means of at least one oxidation control layer (119, 125b). The invention further relates to a laser device (300) comprising such a VCSEL (100) preferably an array of such a VCSELs (100) which are driven by an electrical driving circuit (310). The invention also relates to a method of manufacturing such a VCSEL (100).

Abstract: The invention relates to a Vertical Cavity Surface Emitting Laser (100) comprising a first electrical contact (105), a substrate (110), a first Distributed Bragg Reflector (115), an active layer (120), a second Distributed Bragg Reflector (130) and a second electrical contact (135). The Vertical Cavity Surface Emitting Laser comprises at least one AlyGa(1-y)As-layer with 0.95?y?1 with a thickness of at least 40 nm, wherein the AlyGa(1-y)As-layer is separated by means of at least one oxidation control layer (119, 125b). The invention further relates to a laser device (300) comprising such a VCSEL (100) preferably an array of such a VCSELs (100) which are driven by an electrical driving circuit (310). The invention also relates to a method of manufacturing such a VCSEL (100).

Abstract: The present invention relates to a vertical cavity surface emitting laser device comprising a VCSEL with a monolithically integrated photodiode. The photodiode (2) is formed of a layer sequence of a first n-doped region (6), a p-doped region (7), an intrinsic region (8) and a second n-doped region (9) of a semiconductor material. The photodiode (2) and the laser share a common electrode, which is realized as an Ohmic n-contact (10) at said first n-doped region (6). The proposed device allows less complex manufacturing, resulting in lower manufacturing costs.

Abstract: Some embodiments of the invention provide a Local Preferred Direction (LPD) wiring model for use with one or more EDA tools (such as placing, routing, etc). An LPD wiring model allows at least one wiring layer to have a set of regions that each have a different preferred direction than the particular wiring layer. In addition, each region has a local preferred direction that differs from the local preferred direction of at least one other region in the set. Furthermore, at least two regions have two different polygonal shapes and no region in the set encompasses another region in the set. Some embodiments also provide a Graphical User Interface (GUI) that facilitates a visual presentation of an LPD design layout and provides tools to create and manipulate LPD regions in a design layout.

Abstract: The present invention relates generally to the field of pharmaceutical formulations of antibodies. Specifically, the present invention relates to a stable liquid antibody formulation and its pharmaceutical preparation and use. This invention is exemplified by a liquid formulation of a humanised anti-NGF antibody.

Abstract: The present invention relates to a vertical cavity surface emitting laser device comprising a VCSEL with a monolithically integrated photodiode. The photodiode (2) is formed of a layer sequence of a first n-doped region (6), a p-doped region (7), an intrinsic region (8) and a second n-doped region (9) of a semiconductor material. The photodiode (2) and the laser share a common electrode, which is realized as an Ohmic n-contact (10) at said first n-doped region (6). The proposed device allows less complex manufacturing, resulting in lower manufacturing costs.

Abstract: model for use with one or more EDA tools (such as placing, routing, etc). An LPD wiring model allows at least one wiring layer to have a set of regions that each have a different preferred direction than the particular wiring layer. In addition, each region has a local preferred direction that differs from the local preferred direction of at least one other region in the set. Furthermore, at least two regions have two different polygonal shapes and no region in the set encompasses another region in the set. Some embodiments also provide a Graphical User Interface (GUI) that facilitates a visual presentation of an LPD design layout and provides tools to create and manipulate LPD regions in a design layout.

Abstract: Some embodiments of the invention provide a Local Preferred Direction (LPD) wiring model for use with one or more EDA tools (such as placing, routing, etc). An LPD wiring model allows at least one wiring layer to have a set of regions that each have a different preferred direction than the particular wiring layer. In addition, each region has a local preferred direction that differs from the local preferred direction of at least one other region in the set. Furthermore, at least two regions have two different polygonal shapes and no region in the set encompasses another region in the set. Some embodiments also provide a Graphical User Interface (GUI) that facilitates a visual presentation of an LPD design layout and provides tools to create and manipulate LPD regions in a design layout.

Abstract: A hair styling device with a stretchable, relatively long body portion extending between two ends thereof having a first end clasp member and a second end clasp member each provided at a corresponding one of the opposing ends thereof capable of being at least in part positionable about at least a part of the other. The first and second end clasp members each have a passageway therethrough into which a corresponding body portion end extends with the body portion ends each having a passage blocking object thereon, and being sufficiently narrow to prevent the body end extending therethrough with a blocking object thereon from passing through that narrow part. The blocking member can be a spherical shaped solid wedging the body portion ends into a tapered sides portion of the passageway in each clasp member.

Abstract: A container neck and closure assembly, wherein the container neck (10) comprises a first screw thread (14) on an internal surface thereof and the closure (12) comprises a cylindrical plug (32) for insertion into the container neck, said plug having a second screw thread (36, 37) on an outer surface thereof for engagement with the first screw thread to secure and resecure the closure on the neck.

Abstract: The present invention is directed to methods and apparatus for pest management using remote sensing technology. One aspect of the present invention relates to a method for detecting plant-parasitic nematodes using hyperspectral reflectance data. Another aspect of the present invention relates to a device for determining the population of reniform nematode in a target. The further aspect of the present invention relates to a method for managing nematode population with variable rate applications of nematicides.

Abstract: A threaded container closure assembly, comprising: a container neck (10) having an opening; a-.

Abstract: A container closure assembly includes: a container neck having side walls defining an opening at one end thereof and a lip extending around the opening; a closure for the neck, the closure having a base portion and a threaded skirt portion; a first screw thread on the neck; a second screw thread on an inner surface of the threaded skirt of the closure; said first and second screw threads being configured to enable a user to secure, remove and resecure the closure into a sealing position on the neck by rotation of the cap on the neck; a sealing plug extending from the base portion of the closure inside and substantially concentric with the skirt portion of the closure, wherein the sealing plug includes one or more circumferential sealing ribs on an outer surface of said sealing plug for engagement with an inner surface of the container neck proximate to said lip when the closure is secured on the container neck; a sealing skirt extending from the base portion of the closure intermediate to the sealing plug and

Abstract: The present invention is directed to methods and apparatus for pest management using remote sensing technology. One aspect of the present invention relates to a method for detecting plant-parasitic nematodes using hyperspectral reflectance data. Another aspect of the present invention relates to a device for determining the population of reniform nematode in a target. The further aspect of the present invention relates to a method for managing nematode population with variable rate applications of nematicides.

Abstract: Some embodiments of the invention provide a Local Preferred Direction (LPD) wiring model for use with one or more EDA tools (such as placing, routing, etc). An LPD wiring model allows at least one wiring layer to have a set of regions that each have a different preferred direction than the particular wiring layer. In addition, each region has a local preferred direction that differs from the local preferred direction of at least one other region in the set. Furthermore, at least two regions have two different polygonal shapes and no region in the set encompasses another region in the set. Some embodiments also provide a Graphical User Interface (GUI) that facilitates a visual presentation of an LPD design layout and provides tools to create and manipulate LPD regions in a design layout.

Abstract: A hair styling device with a stretchable, relatively long body portion extending between two ends thereof having a first end clasp member and a second end clasp member each provided at a corresponding one of the opposing ends thereof capable of being at least in part positionable about at least a part of the other. The first and second end clasp members each have a passageway therethrough into which a corresponding body portion end extends with the body portion ends each having a passage blocking object thereon, and being sufficiently narrow to prevent the body end extending therethrough with a blocking object thereon from passing through that narrow part. The blocking member can be a spherical shaped solid wedging the body portion ends into a tapered sides portion of the passageway in each clasp member.

Abstract: A closure assembly includes: a vessel opening; a closure for said opening, the closure having a base portion and a skirt portion; a first screw thread on the opening, said first screw thread having one or more first thread segments; a second screw thread on an inner surface of the skirt of the closure, said second screw thread having one or more second thread segments; said first and second screw threads being configured to enable a user to secure, remove and resecure the closure into a sealing position on the opening by rotation of the closure on the opening; wherein the first thread segments are shorter than said second thread segments; and wherein the second thread segments are each made up of one or more radially spaced projecting portions, each said portion extending radially no more than about 60° around the closure skirt.