Patents by Inventor Roger Narayan
Roger Narayan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220151516Abstract: Methods, structures, and systems are disclosed for biosensing and drug delivery techniques. In one aspect, a device for detecting an analyte and/or releasing a biochemical into a biological fluid can include an array of hollowed needles, in which each needle includes a protruded needle structure including an exterior wall forming a hollow interior and an opening at a terminal end of the protruded needle structure that exposes the hollow interior, and a probe inside the exterior wall to interact with one or more chemical or biological substances that come in contact with the probe via the opening to produce a probe sensing signal, and an array of wires that are coupled to probes of the array of hollowed needles, respectively, each wire being electrically conductive to transmit the probe sensing signal produced by a respective probe.Type: ApplicationFiled: February 4, 2022Publication date: May 19, 2022Inventors: Joseph Wang, Joshua Ray Windmiller, Roger Narayan, Phillip Miller, Ronen Polsky, Thayne L. Edwards
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Publication number: 20190125223Abstract: Methods, structures, and systems are disclosed for biosensing and drug delivery techniques. In one aspect, a device for detecting an analyte and/or releasing a biochemical into a biological fluid can include an array of hollowed needles, in which each needle includes a protruded needle structure including an exterior wall forming a hollow interior and an opening at a terminal end of the protruded needle structure that exposes the hollow interior, and a probe inside the exterior wall to interact with one or more chemical or biological substances that come in contact with the probe via the opening to produce a probe sensing signal, and an array of wires that are coupled to probes of the array of hollowed needles, respectively, each wire being electrically conductive to transmit the probe sensing signal produced by a respective probe.Type: ApplicationFiled: October 24, 2018Publication date: May 2, 2019Inventors: Joseph Wang, Joshua Ray Windmiller, Roger Narayan, Phillip Miller, Ronen Polsky, Thayne L. Edwards
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Publication number: 20180369136Abstract: Various implementations include a transdermal drug delivery system for treating basal cell carcinoma. The system includes a pharmacologic agent and an array of microneedles for creating pores in the skin surface and the stratum corneum layer of the epidermis, thereby enabling transdermal delivery of the pharmacologic agent. The pharmacologic agent includes itraconazole and/or vitamin D3. Various implementations also include a method of treating basal cell carcinoma in a subject. The method includes: (1) applying an array of microneedles to a skin site having basal cell carcinoma, such that the microneedles penetrate the surface of the skin and the stratum corneum layer of the skin; and (2) administering a pharmaceutical composition to the subject intradermally through openings in the skin formed by the microneedles, wherein the pharmaceutical composition comprises a therapeutically effective amount of a pharmacologic chosen from itraconazole, vitamin D3, or a combination thereof.Type: ApplicationFiled: December 27, 2016Publication date: December 27, 2018Inventors: Roger Narayan, Russell Hall, Yunyan Zhang
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Patent number: 10136846Abstract: Methods, structures, and systems are disclosed for biosensing and drug delivery techniques. In one aspect, a device for detecting an analyte and/or releasing a biochemical into a biological fluid can include an array of hollowed needles, in which each needle includes a protruded needle structure including an exterior wall forming a hollow interior and an opening at a terminal end of the protruded needle structure that exposes the hollow interior, and a probe inside the exterior wall to interact with one or more chemical or biological substances that come in contact with the probe via the opening to produce a probe sensing signal, and an array of wires that are coupled to probes of the array of hollowed needles, respectively, each wire being electrically conductive to transmit the probe sensing signal produced by a respective probe.Type: GrantFiled: August 25, 2017Date of Patent: November 27, 2018Assignees: The Regents of the University of California, North Carolina State University, National Technology & Engineering Solutions of Sandia, LLCInventors: Joseph Wang, Joshua Ray Windmiller, Roger Narayan, Phillip Miller, Ronen Polsky, Thayne L. Edwards
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Publication number: 20170347925Abstract: Methods, structures, and systems are disclosed for biosensing and drug delivery techniques. In one aspect, a device for detecting an analyte and/or releasing a biochemical into a biological fluid can include an array of hollowed needles, in which each needle includes a protruded needle structure including an exterior wall forming a hollow interior and an opening at a terminal end of the protruded needle structure that exposes the hollow interior, and a probe inside the exterior wall to interact with one or more chemical or biological substances that come in contact with the probe via the opening to produce a probe sensing signal, and an array of wires that are coupled to probes of the array of hollowed needles, respectively, each wire being electrically conductive to transmit the probe sensing signal produced by a respective probe.Type: ApplicationFiled: August 25, 2017Publication date: December 7, 2017Applicants: The Regents of the University of California, North Carolina State University, National Technology & Engineering Solutions of San Sandia, LLCInventors: Joseph Wang, Joshua Ray Windmiller, Roger Narayan, Phillip Miller, Ronen Polsky, Thayne L. Edwards
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Patent number: 9743870Abstract: Methods, structures, and systems are disclosed for biosensing and drug delivery techniques. In one aspect, a device for detecting an analyte and/or releasing a biochemical into a biological fluid can include an array of hollowed needles, in which each needle includes a protruded needle structure including an exterior wall forming a hollow interior and an opening at a terminal end of the protruded needle structure that exposes the hollow interior, and a probe inside the exterior wall to interact with one or more chemical or biological substances that come in contact with the probe via the opening to produce a probe sensing signal, and an array of wires that are coupled to probes of the array of hollowed needles, respectively, each wire being electrically conductive to transmit the probe sensing signal produced by a respective probe.Type: GrantFiled: December 10, 2015Date of Patent: August 29, 2017Assignees: The Regents of the University of California, North Carolina State University, National Technology & Engineering Solutions of Sandia, LLCInventors: Joseph Wang, Joshua Ray Windmiller, Roger Narayan, Philip Miller, Ronen Polsky, Thayne L. Edwards
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Patent number: 9737247Abstract: Methods, structures, and systems are disclosed for biosensing and drug delivery techniques. In one aspect, a^ device for detecting an analyte and/or releasing a biochemical into a biological fluid can include an array of hollowed needles, in which each needle includes a protruded needle structure including an exterior wall forming a hollow interior and an opening at a terminal end of the protruded needle structure that exposes the hollow interior, and a probe inside the exterior wall to interact with one or more chemical or biological substances that come in contact with the probe via the opening to produce a probe sensing signal, and an array of wires that are coupled to probes of the array of hollowed needles, respectively, each wire being electrically conductive to transmit the probe sensing signal produced by a respective probe.Type: GrantFiled: August 31, 2012Date of Patent: August 22, 2017Assignees: The Regents of the University of California, North Carolina State University, National Technology & Engineering Solutions of Sandia, LLCInventors: Joseph Wang, Joshua Ray Windmiller, Roger Narayan, Philip Miller, Ronen Polsky, Thayne L. Edwards
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Publication number: 20160095541Abstract: Methods, structures, and systems are disclosed for biosensing and drug delivery techniques. In one aspect, a device for detecting an analyte and/or releasing a biochemical into a biological fluid can include an array of hollowed needles, in which each needle includes a protruded needle structure including an exterior wall forming a hollow interior and an opening at a terminal end of the protruded needle structure that exposes the hollow interior, and a probe inside the exterior wall to interact with one or more chemical or biological substances that come in contact with the probe via the opening to produce a probe sensing signal, and an array of wires that are coupled to probes of the array of hollowed needles, respectively, each wire being electrically conductive to transmit the probe sensing signal produced by a respective probe.Type: ApplicationFiled: December 10, 2015Publication date: April 7, 2016Inventors: Joseph Wang, Joshua Ray Windmiller, Roger Narayan, Philip Miller, Ronen Polsky, Thayne L. Edwards
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Publication number: 20140336487Abstract: Methods, structures, and systems are disclosed for biosensing and drug delivery techniques. In one aspect, a? device for detecting an analyte and/or releasing a biochemical into a biological fluid can include an array of hollowed needles, in which each needle includes a protruded needle structure including an exterior wall forming a hollow interior and an opening at a terminal end of the protruded needle structure that exposes the hollow interior, and a probe inside the exterior wall to interact with one or more chemical or biological substances that come in contact with the probe via the opening to produce a probe sensing signal, and an array of wires that are coupled to probes of the array of hollowed needles, respectively, each wire being electrically conductive to transmit the probe sensing signal produced by a respective probe.Type: ApplicationFiled: August 31, 2012Publication date: November 13, 2014Inventors: Joseph Wang, Joshua Ray Windmiller, Roger Narayan, Phillip Miller, Ronen Polsky, Thayne L. Edwards