Patents by Inventor Roger R. Reddel

Roger R. Reddel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein and gene involved in myocyte differentiation
    Publication number: 20040086934
    Abstract: A novel gene was unexpectedly isolated in an attempt to isolate a gene specifically expressed in immortalized cells via antibody screening using an antibody raised against a protein occurring specifically in immortalized cells. The gene thus isolated shares no sequence homology with the entries deposited in the database and was strongly expressed in skeletal muscles and undifferentiated cells. The protein encoded by this gene inhibits the differentiation of myoblasts into myotubes. It also inhibits the transactivation function of p53, a transcription factor involved in tumor suppression.
    Type: Application
    Filed: December 1, 2003
    Publication date: May 6, 2004
    Inventors: Renu Wadhwa, Sunil C. Kaul, Roger R. Reddel
  • Protein and gene involved in myocyte differentiation
    Publication number: 20040086933
    Abstract: A novel gene was unexpectedly isolated in an attempt to isolate a gene specifically expressed in immortalized cells via antibody screening using an antibody raised against a protein occurring specifically in immortalized cells. The gene thus isolated shares no sequence homology with the entries deposited in the database and was strongly expressed in skeletal muscles and undifferentiated cells. The protein encoded by this gene inhibits the differentiation of myoblasts into myotubes. It also inhibits the transactivation function of p53, a transcription factor involved in tumor suppression.
    Type: Application
    Filed: December 1, 2003
    Publication date: May 6, 2004
    Applicant: Chugai Seiyaku Kabushiki Kaisha, a Japan corporation
    Inventors: Renu Wadhwa, Sunil C. Kaul, Roger R. Reddel
  • Protein and gene involved in myocyte differentiation
    Patent number: 6670450
    Abstract: A gene was unexpectedly isolated in an attempt to isolate a gene specifically expressed in immortalized cells via antibody screening using an antibody raised against a protein occurring specifically in immortalized cells. The gene thus isolated shares no sequence homology with the entries deposited in the database and was strongly expressed in skeletal muscles and undifferentiated cells. The protein encoded by this gene inhibits the differentiation of myoblasts into myotubes. It also inhibits the transactivation function of p53, a transcription factor involved in tumor suppression.
    Type: Grant
    Filed: October 6, 2000
    Date of Patent: December 30, 2003
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Renu Wadhwa, Sunil C. Kaul, Roger R. Reddel
  • Immortalized non-tumorigenic human bronchial epithelial cell lines
    Patent number: 5443954
    Abstract: Immortalized human bronchial epithelial and human mesothelial cell lines have been obtained. Various uses of these cell lines have been described.
    Type: Grant
    Filed: January 2, 1991
    Date of Patent: August 22, 1995
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Roger R. Reddel, Yang Ke, Johng S. Rhim, Douglas E. Brash, Robert T. Su, John F. Lechner, Brenda I. Gerwin, Curtis C. Harris, Paul Amstad
  • Immortalized human bronchial epitherial mesothelial cell lines
    Patent number: 4885238
    Abstract: Immortalized human bronchial epithelial and human mesothelial cell lines have been obtained. Various uses of these cell lines have been described.
    Type: Grant
    Filed: October 30, 1987
    Date of Patent: December 5, 1989
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Roger R. Reddel, Ke Yang, Johng S. Rhim, Douglas Brash, Robert T. Su, John F. Lechner, Brenda I. Gerwin, Curtis C. Harris, Paul Amstad