Abstract: In various embodiments, disclosed herein is an artificial cornea, comprising an optic zone that is similar in thickness to a natural cornea and a peripheral skirt having a thickness less than the thickness of the optic zone, where the surfaces of the optic zone and peripheral skirt comprise one or more microstructures or nanostructures. In various embodiments, further disclosed herein are methods of manufacturing nanostructures on an artificial cornea, as well as treating a disease by providing an artificial cornea having one or more microstructures and/or nanostructures.

Abstract: In various embodiments, disclosed herein is an artificial cornea, comprising an optic zone that is similar in thickness to a natural cornea and a peripheral skirt having a thickness less than the thickness of the optic zone, where the surfaces of the optic zone and peripheral skirt comprise one or more microstructures or nanostructures. In various embodiments, further disclosed herein are methods of manufacturing nanostructures on an artificial cornea, as well as treating a disease by providing an artificial cornea having one or more microstructures and/or nanostructures.

Abstract: A system and method of resecting corneal tissue for transplantation is disclosed. In each of the recipient cornea and the donor cornea, an annular incision is made at a predetermined incision depth. A first sidecut incision is made in each cornea, running from the outer periphery of the annular incision to one of the anterior corneal surface or the posterior corneal surface. The first sidecut incision forms an acute angle with the annular incision. A second sidecut incision is also made in each cornea, running from the inner periphery of the annular incision to the other of the anterior corneal surface or the posterior corneal surface. The second sidecut incision forms an acute angle with the annular incision. The combination of the incisions in each cornea resects corneal tissue from the recipient cornea and donor tissue from the donor cornea. The donor tissue is grafted into the recipient cornea.

Abstract: A system and method of resecting corneal tissue for transplantation is disclosed. In each of the recipient cornea and the donor cornea, an annular incision is made at a predetermined incision depth. A first sidecut incision is made in each cornea, running from the outer periphery of the annular incision to one of the anterior corneal surface or the posterior corneal surface. The first sidecut incision forms an acute angle with the annular incision. A second sidecut incision is also made in each cornea, running from the inner periphery of the annular incision to the other of the anterior corneal surface or the posterior corneal surface. The second sidecut incision forms an acute angle with the annular incision. The combination of the incisions in each cornea resects corneal tissue from the recipient cornea and donor tissue from the donor cornea. The donor tissue is grafted into the recipient cornea.

Abstract: A system and method for marking corneal tissue in a transplant procedure is disclosed. Sidecut incisions are made in each of the donor cornea and the recipient cornea. Crosscut incisions are made across the sidecut incision in each cornea. Corneal tissue which is at least partially bounded by the sidecut incision is resected from the recipient cornea. Part of the crosscut incision made in the recipient cornea extends beyond the resected corneal tissue. Donor tissue which is at least partially bounded by the sidecut incision is resected from the donor cornea. Part of the crosscut incision made in the donor cornea is in the resected donor tissue. The donor tissue is then grafted into the recipient cornea.

Abstract: A laser system for treating an eye having a cornea, the laser system including a laser beam source capable of generating a laser beam, an eye position detector which includes at least a corneal tracker, the corneal tracker being responsive to movement of an anterior portion of the cornea, the corneal tracker constructed to detect movement of the cornea based on a set of spaced apart optical manifestations from the outer surface of the anterior portion of the cornea, and a beam controller, the beam controller being responsive to the eye position detector to direct the laser beam with controlled energy from the laser beam source to a desired location on the eye.